[Hub]/) : Traits : Impedance of arm (left) : ← →

chr3:37,692,342-39,280,382

Best TWAS P=1.57e-30 · Best GWAS P=2.67e-30 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Testis	EXOG	0.35	0.28	lasso	5	0.26	8.1e-12	11.44	11.5	2.0e-30	1.00	0.01	0.99	TRUE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EXOG	0.02	0.02	blup	56	0.01	1.0e-02	11.17	11.5	1.6e-30	0.96	0.02	0.89	FALSE
5	GTEx	Brain Frontal Cortex BA9	EXOG	0.18	0.08	lasso	4	0.05	1.7e-02	11.41	11.4	4.1e-30	0.99	0.02	0.91	FALSE
13	GTEx	Stomach	EXOG	0.14	0.05	lasso	6	0.02	2.5e-02	11.09	11.3	1.7e-29	1.00	0.01	0.97	FALSE
8	GTEx	Esophagus Mucosa	EXOG	0.13	0.05	lasso	3	0.03	5.0e-03	11.09	11.1	1.1e-28	0.98	0.05	0.88	FALSE
15	GTEx	Thyroid	EXOG	0.19	0.20	lasso	3	0.19	2.9e-14	11.07	11.1	1.3e-28	0.98	0.02	0.98	FALSE
3	GTEx	Brain Cerebellum	EXOG	0.19	0.23	enet	4	0.21	7.7e-07	11.09	11.0	3.0e-28	0.99	0.06	0.92	FALSE
33	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	XYLB	0.05	0.03	lasso	4	0.02	2.4e-03	10.89	-11.0	3.2e-28	-0.93	0.02	0.97	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	ACVR2B	0.02	0.00	blup	49	0.01	1.6e-02	11.02	-11.0	4.9e-28	-0.92	0.03	0.46	FALSE
16	NTR	Blood	ACVR2B	0.02	0.02	lasso	3	0.02	5.6e-07	10.09	11.0	5.3e-28	0.95	0.02	0.98	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100128640	0.07	0.03	blup	28	0.03	1.0e-03	11.43	-10.9	1.1e-27	-0.96	0.01	0.98	FALSE
17	NTR	Blood	EXOG	0.02	0.03	lasso	6	0.03	1.0e-09	10.52	-10.9	1.4e-27	-0.89	0.30	0.70	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ACVR2B	0.08	0.08	enet	15	0.09	9.6e-11	10.52	-10.7	8.5e-27	-0.88	0.23	0.77	FALSE
10	GTEx	Ovary	EXOG	0.33	0.25	lasso	8	0.21	8.1e-06	10.09	10.7	1.3e-26	0.90	0.08	0.75	FALSE
6	GTEx	Breast Mammary Tissue	EXOG	0.08	0.06	enet	10	0.05	8.6e-04	8.18	10.6	2.0e-26	0.90	0.04	0.93	FALSE
28	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EXOG	0.14	0.09	blup	56	0.09	9.5e-06	11.07	10.6	3.9e-26	0.88	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	XYLB	0.05	0.06	enet	7	0.05	3.5e-06	11.23	-10.5	6.1e-26	-0.95	0.00	1.00	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	EXOG	0.10	0.13	lasso	2	0.12	4.8e-15	11.08	10.5	6.2e-26	0.98	0.03	0.97	FALSE
4	GTEx	Brain Cerebellum	ACVR2B-AS1	0.25	0.07	lasso	6	0.10	8.3e-04	11.07	10.5	1.0e-25	0.91	0.03	0.95	FALSE
27	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	XYLB	0.03	0.03	blup	82	0.02	5.1e-03	11.26	-10.5	1.4e-25	-0.91	0.01	0.98	FALSE
2	GTEx	Adipose Subcutaneous	EXOG	0.10	0.00	enet	12	0.00	1.3e-01	11.09	10.4	2.1e-25	0.68	0.02	0.77	FALSE
12	GTEx	Pancreas	EXOG	0.22	0.08	enet	15	0.03	2.6e-02	11.37	10.3	1.0e-24	0.91	0.03	0.95	FALSE
18	NTR	Blood	XYLB	0.05	0.06	lasso	3	0.06	6.2e-18	10.09	10.2	2.0e-24	0.87	0.69	0.31	FALSE
29	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC100128640	0.09	0.05	lasso	2	0.03	1.7e-02	10.09	-10.1	6.4e-24	-0.86	0.02	0.47	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	EXOG	0.04	0.01	blup	56	0.03	2.2e-04	10.09	9.9	4.2e-23	0.82	0.02	0.85	FALSE
9	GTEx	Nerve Tibial	EXOG	0.10	0.00	lasso	5	0.00	1.7e-01	11.09	9.8	1.1e-22	0.87	0.04	0.79	FALSE
22	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	XYLB	0.06	0.05	blup	82	0.04	5.2e-03	10.89	-9.8	1.1e-22	-0.85	0.04	0.62	FALSE
35	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EXOG	0.10	0.02	blup	56	0.03	2.1e-02	4.12	9.8	1.5e-22	0.82	0.02	0.57	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC100128640	0.08	0.02	blup	28	0.03	2.6e-04	11.41	-9.6	7.7e-22	-0.87	0.01	0.98	FALSE
7	GTEx	Colon Transverse	XYLB	0.08	0.03	enet	15	0.05	1.7e-03	11.41	-9.6	1.3e-21	-0.85	0.02	0.96	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	EXOG	0.11	0.05	blup	56	0.10	9.5e-10	11.09	9.5	3.1e-21	0.83	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EXOG	0.08	0.02	blup	56	0.06	9.1e-08	11.43	8.7	4.7e-18	0.75	0.01	0.99	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	XYLB	0.05	0.02	blup	82	0.03	7.2e-04	10.82	-8.1	5.9e-16	-0.73	0.05	0.92	FALSE
11	GTEx	Pancreas	XYLB	0.14	0.15	enet	6	0.13	5.7e-06	8.02	-7.5	7.7e-14	-0.51	0.18	0.58	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	EXOG	0.22	0.00	blup	56	0.06	2.0e-04	5.98	7.1	1.1e-12	0.49	0.01	0.21	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	XYLB	0.08	0.01	enet	16	0.05	4.3e-03	10.92	-7.1	1.4e-12	-0.69	0.03	0.64	FALSE
21	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EXOG	0.07	0.01	blup	56	0.04	4.6e-04	7.01	6.7	1.6e-11	0.68	0.02	0.75	FALSE
20	YFS	Blood	ACVR2B	0.02	0.00	blup	447	0.00	2.4e-02	10.06	6.6	4.9e-11	0.66	0.05	0.78	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	EXOG	0.06	0.01	blup	56	0.03	3.7e-04	7.01	5.8	8.6e-09	0.59	0.18	0.45	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	XYLB	0.05	0.02	blup	82	0.02	1.4e-03	0.59	-5.6	1.9e-08	-0.51	0.09	0.14	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	XYLB	0.11	0.05	blup	82	0.05	4.7e-04	0.59	-5.2	2.0e-07	-0.59	0.02	0.55	FALSE