[Hub]/) : Traits : Impedance of arm (left) :

chr3:37,692,342-39,280,382

Best TWAS P=1.57e-30 · Best GWAS P=2.67e-30 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ACVR2B 0.08 0.08 enet 15 0.09 9.6e-11 10.52 -10.7 8.5e-27 -0.88 0.23 0.77 FALSE
2 GTEx Adipose Subcutaneous EXOG 0.10 0.00 enet 12 0.00 1.3e-01 11.09 10.4 2.1e-25 0.68 0.02 0.77 FALSE
3 GTEx Brain Cerebellum EXOG 0.19 0.23 enet 4 0.21 7.7e-07 11.09 11.0 3.0e-28 0.99 0.06 0.92 FALSE
4 GTEx Brain Cerebellum ACVR2B-AS1 0.25 0.07 lasso 6 0.10 8.3e-04 11.07 10.5 1.0e-25 0.91 0.03 0.95 FALSE
5 GTEx Brain Frontal Cortex BA9 EXOG 0.18 0.08 lasso 4 0.05 1.7e-02 11.41 11.4 4.1e-30 0.99 0.02 0.91 FALSE
6 GTEx Breast Mammary Tissue EXOG 0.08 0.06 enet 10 0.05 8.6e-04 8.18 10.6 2.0e-26 0.90 0.04 0.93 FALSE
7 GTEx Colon Transverse XYLB 0.08 0.03 enet 15 0.05 1.7e-03 11.41 -9.6 1.3e-21 -0.85 0.02 0.96 FALSE
8 GTEx Esophagus Mucosa EXOG 0.13 0.05 lasso 3 0.03 5.0e-03 11.09 11.1 1.1e-28 0.98 0.05 0.88 FALSE
9 GTEx Nerve Tibial EXOG 0.10 0.00 lasso 5 0.00 1.7e-01 11.09 9.8 1.1e-22 0.87 0.04 0.79 FALSE
10 GTEx Ovary EXOG 0.33 0.25 lasso 8 0.21 8.1e-06 10.09 10.7 1.3e-26 0.90 0.08 0.75 FALSE
11 GTEx Pancreas XYLB 0.14 0.15 enet 6 0.13 5.7e-06 8.02 -7.5 7.7e-14 -0.51 0.18 0.58 FALSE
12 GTEx Pancreas EXOG 0.22 0.08 enet 15 0.03 2.6e-02 11.37 10.3 1.0e-24 0.91 0.03 0.95 FALSE
13 GTEx Stomach EXOG 0.14 0.05 lasso 6 0.02 2.5e-02 11.09 11.3 1.7e-29 1.00 0.01 0.97 FALSE
14 GTEx Testis EXOG 0.35 0.28 lasso 5 0.26 8.1e-12 11.44 11.5 2.0e-30 1.00 0.01 0.99 TRUE
15 GTEx Thyroid EXOG 0.19 0.20 lasso 3 0.19 2.9e-14 11.07 11.1 1.3e-28 0.98 0.02 0.98 FALSE
16 NTR Blood ACVR2B 0.02 0.02 lasso 3 0.02 5.6e-07 10.09 11.0 5.3e-28 0.95 0.02 0.98 FALSE
17 NTR Blood EXOG 0.02 0.03 lasso 6 0.03 1.0e-09 10.52 -10.9 1.4e-27 -0.89 0.30 0.70 FALSE
18 NTR Blood XYLB 0.05 0.06 lasso 3 0.06 6.2e-18 10.09 10.2 2.0e-24 0.87 0.69 0.31 FALSE
19 ROSMAP Brain Pre-frontal Cortex EXOG 0.10 0.13 lasso 2 0.12 4.8e-15 11.08 10.5 6.2e-26 0.98 0.03 0.97 FALSE
20 YFS Blood ACVR2B 0.02 0.00 blup 447 0.00 2.4e-02 10.06 6.6 4.9e-11 0.66 0.05 0.78 FALSE
21 The Cancer Genome Atlas Bladder Urothelial Carcinoma EXOG 0.07 0.01 blup 56 0.04 4.6e-04 7.01 6.7 1.6e-11 0.68 0.02 0.75 FALSE
22 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma XYLB 0.06 0.05 blup 82 0.04 5.2e-03 10.89 -9.8 1.1e-22 -0.85 0.04 0.62 FALSE
23 The Cancer Genome Atlas Colon Adenocarcinoma EXOG 0.22 0.00 blup 56 0.06 2.0e-04 5.98 7.1 1.1e-12 0.49 0.01 0.21 FALSE
24 The Cancer Genome Atlas Colon Adenocarcinoma XYLB 0.11 0.05 blup 82 0.05 4.7e-04 0.59 -5.2 2.0e-07 -0.59 0.02 0.55 FALSE
25 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EXOG 0.04 0.01 blup 56 0.03 2.2e-04 10.09 9.9 4.2e-23 0.82 0.02 0.85 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EXOG 0.08 0.02 blup 56 0.06 9.1e-08 11.43 8.7 4.7e-18 0.75 0.01 0.99 FALSE
27 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XYLB 0.03 0.03 blup 82 0.02 5.1e-03 11.26 -10.5 1.4e-25 -0.91 0.01 0.98 FALSE
28 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EXOG 0.14 0.09 blup 56 0.09 9.5e-06 11.07 10.6 3.9e-26 0.88 0.01 0.99 FALSE
29 The Cancer Genome Atlas Liver Hepatocellular Carcinoma LOC100128640 0.09 0.05 lasso 2 0.03 1.7e-02 10.09 -10.1 6.4e-24 -0.86 0.02 0.47 FALSE
30 The Cancer Genome Atlas Lung Adenocarcinoma EXOG 0.06 0.01 blup 56 0.03 3.7e-04 7.01 5.8 8.6e-09 0.59 0.18 0.45 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma XYLB 0.05 0.02 blup 82 0.02 1.4e-03 0.59 -5.6 1.9e-08 -0.51 0.09 0.14 FALSE
32 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EXOG 0.02 0.02 blup 56 0.01 1.0e-02 11.17 11.5 1.6e-30 0.96 0.02 0.89 FALSE
33 The Cancer Genome Atlas Lung Squamous Cell Carcinoma XYLB 0.05 0.03 lasso 4 0.02 2.4e-03 10.89 -11.0 3.2e-28 -0.93 0.02 0.97 FALSE
34 The Cancer Genome Atlas Pancreatic Adenocarcinoma XYLB 0.08 0.01 enet 16 0.05 4.3e-03 10.92 -7.1 1.4e-12 -0.69 0.03 0.64 FALSE
35 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EXOG 0.10 0.02 blup 56 0.03 2.1e-02 4.12 9.8 1.5e-22 0.82 0.02 0.57 FALSE
36 The Cancer Genome Atlas Prostate Adenocarcinoma LOC100128640 0.08 0.02 blup 28 0.03 2.6e-04 11.41 -9.6 7.7e-22 -0.87 0.01 0.98 FALSE
37 The Cancer Genome Atlas Prostate Adenocarcinoma XYLB 0.05 0.06 enet 7 0.05 3.5e-06 11.23 -10.5 6.1e-26 -0.95 0.00 1.00 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma ACVR2B 0.02 0.00 blup 49 0.01 1.6e-02 11.02 -11.0 4.9e-28 -0.92 0.03 0.46 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma EXOG 0.11 0.05 blup 56 0.10 9.5e-10 11.09 9.5 3.1e-21 0.83 0.02 0.98 FALSE
40 The Cancer Genome Atlas Thyroid Carcinoma LOC100128640 0.07 0.03 blup 28 0.03 1.0e-03 11.43 -10.9 1.1e-27 -0.96 0.01 0.98 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma XYLB 0.05 0.02 blup 82 0.03 7.2e-04 10.82 -8.1 5.9e-16 -0.73 0.05 0.92 FALSE