Best TWAS P=7.01e-12 · Best GWAS P=1.04e-08 conditioned to 0.00705
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | PTPN13 | 0.15 | 0.05 | lasso | 3 | 0.06 | 2.8e-03 | -5.4 | 5.5 | 3.9e-08 | -0.72 | 0.04 | 0.76 | FALSE |
| 2 | GTEx | Artery Aorta | MAPK10 | 0.15 | 0.17 | enet | 16 | 0.17 | 1.4e-09 | -5.1 | 5.6 | 2.0e-08 | -0.81 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Colon Sigmoid | MAPK10 | 0.25 | 0.11 | lasso | 8 | 0.07 | 1.6e-03 | -5.1 | 5.4 | 6.4e-08 | -0.74 | 0.02 | 0.94 | FALSE |
| 4 | GTEx | Nerve Tibial | MAPK10 | 0.08 | 0.01 | enet | 17 | 0.03 | 1.7e-03 | -5.4 | 5.1 | 2.7e-07 | -0.63 | 0.02 | 0.95 | FALSE |
| 5 | GTEx | Ovary | PTPN13 | 0.18 | -0.01 | enet | 29 | 0.07 | 8.4e-03 | -5.4 | 6.9 | 7.0e-12 | -0.49 | 0.04 | 0.63 | TRUE |
| 6 | GTEx | Thyroid | PTPN13 | 0.41 | 0.31 | lasso | 6 | 0.30 | 3.2e-23 | -5.4 | -5.2 | 2.2e-07 | 0.81 | 0.02 | 0.98 | FALSE |