Best TWAS P=1.6e-09 · Best GWAS P=4.03e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DLST | 0.09 | 0.11 | lasso | 2 | 0.11 | 4.0e-13 | -6.3 | 6.0 | 1.6e-09 | -0.98 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | RPS6KL1 | 0.08 | 0.08 | enet | 11 | 0.07 | 1.5e-04 | 5.1 | 5.8 | 7.7e-09 | -0.94 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Testis | AREL1 | 0.20 | 0.14 | enet | 34 | 0.13 | 2.1e-06 | 5.0 | 5.8 | 6.0e-09 | -0.84 | 0.23 | 0.77 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | PROX2 | 0.07 | 0.01 | blup | 41 | 0.03 | 4.5e-03 | -6.2 | 5.3 | 1.2e-07 | -0.87 | 0.00 | 0.90 | FALSE |