Best TWAS P=1.57e-10 · Best GWAS P=7.72e-14 conditioned to 2.43e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | BBS4 | 0.27 | 0.02 | enet | 21 | 0.05 | 2.1e-02 | -4.8 | -6.4 | 1.6e-10 | 0.69 | 0.05 | 0.52 | TRUE |
| 2 | GTEx | Spleen | NEO1 | 0.39 | 0.00 | lasso | 9 | 0.01 | 2.0e-01 | 5.4 | -5.5 | 4.7e-08 | 0.25 | 0.05 | 0.11 | FALSE |
| 3 | GTEx | Testis | ADPGK-AS1 | 0.17 | 0.05 | lasso | 4 | 0.03 | 1.3e-02 | -4.4 | 6.2 | 4.2e-10 | -0.72 | 0.02 | 0.90 | FALSE |
| 4 | NTR | Blood | NEO1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 4.1e-06 | 5.4 | -5.2 | 2.0e-07 | 0.25 | 0.88 | 0.06 | FALSE |