[Hub]/) : Traits : Leg fat percentage (right) :

chr15:83,632,164-85,883,064

Best TWAS P=3.4e-12 · Best GWAS P=5.11e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADAMTSL3 0.10 0.04 lasso 4 0.04 8.7e-06 -6.9 -6.2 6.2e-10 0.60 0.22 0.14 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC388152 0.14 0.14 enet 20 0.18 6.7e-22 3.3 -5.2 1.7e-07 0.48 1.00 0.00 TRUE
3 GTEx Artery Tibial SCAND2P 0.12 0.05 enet 16 0.08 8.7e-07 -2.9 -5.2 1.8e-07 0.39 0.64 0.07 FALSE
4 GTEx Brain Cerebellum AC103965.1 0.13 0.02 enet 21 0.01 2.1e-01 3.3 -5.6 2.4e-08 0.49 0.08 0.43 FALSE
5 GTEx Brain Cortex GOLGA6L4 0.42 0.21 lasso 7 0.28 2.8e-08 -5.4 -6.4 1.9e-10 0.61 0.20 0.70 TRUE
6 GTEx Brain Nucleus accumbens basal ganglia GOLGA6L4 0.21 0.04 lasso 5 0.09 2.3e-03 -6.9 -5.6 2.0e-08 0.55 0.06 0.18 FALSE
7 GTEx Breast Mammary Tissue (Male) GOLGA6L4 0.23 0.07 lasso 2 0.12 8.3e-04 -5.4 -5.6 2.2e-08 0.49 0.07 0.31 TRUE
8 GTEx Breast Mammary Tissue (Male) AC103965.1 0.24 0.14 lasso 4 0.11 1.4e-03 3.2 -5.4 8.0e-08 0.53 0.07 0.57 TRUE
9 GTEx Cells Transformed fibroblasts AC103965.1 0.15 0.09 lasso 7 0.11 1.3e-08 3.3 -5.2 1.7e-07 0.50 0.75 0.24 FALSE
10 GTEx Colon Transverse AC103965.1 0.15 0.07 enet 33 0.06 7.1e-04 -4.8 -5.5 3.7e-08 0.45 0.11 0.45 TRUE
11 GTEx Esophagus Mucosa CSPG4P11 0.21 0.01 enet 28 0.08 3.7e-06 -4.8 -5.2 2.0e-07 0.49 0.70 0.21 TRUE
12 GTEx Esophagus Muscularis UBE2Q2P1 0.34 0.03 lasso 7 0.15 1.9e-09 3.7 7.0 3.4e-12 -0.35 0.16 0.67 TRUE
13 GTEx Pancreas RP11-182J1.16 0.08 -0.01 enet 11 -0.01 7.9e-01 -4.8 -5.2 2.0e-07 0.58 0.03 0.51 FALSE
14 GTEx Prostate CSPG4P11 0.34 0.07 enet 13 0.18 2.3e-05 -1.0 -5.3 1.1e-07 0.36 0.07 0.67 FALSE
15 GTEx Skin Sun Exposed Lower leg AC103965.1 0.33 0.17 enet 24 0.23 4.8e-19 3.3 -5.7 1.5e-08 0.49 1.00 0.00 TRUE
16 GTEx Small Intestine Terminal Ileum RP11-182J1.14 0.26 0.01 enet 27 0.12 1.3e-03 -6.9 5.3 1.0e-07 -0.41 0.05 0.24 TRUE
17 GTEx Spleen GOLGA6L4 0.55 0.20 enet 19 0.40 2.6e-11 -5.0 -5.8 5.6e-09 0.46 0.88 0.03 TRUE
18 GTEx Whole Blood GOLGA6L4 0.12 0.08 enet 16 0.11 2.1e-10 -4.8 -5.8 8.8e-09 0.49 0.86 0.14 FALSE