[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr15:83,632,164-85,883,064

Best TWAS P=3.4e-12 · Best GWAS P=5.11e-18 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Esophagus Muscularis	UBE2Q2P1	0.34	0.03	lasso	7	0.15	1.9e-09	3.7	7.0	3.4e-12	-0.35	0.16	0.67	TRUE
5	GTEx	Brain Cortex	GOLGA6L4	0.42	0.21	lasso	7	0.28	2.8e-08	-5.4	-6.4	1.9e-10	0.61	0.20	0.70	TRUE
17	GTEx	Spleen	GOLGA6L4	0.55	0.20	enet	19	0.40	2.6e-11	-5.0	-5.8	5.6e-09	0.46	0.88	0.03	TRUE
15	GTEx	Skin Sun Exposed Lower leg	AC103965.1	0.33	0.17	enet	24	0.23	4.8e-19	3.3	-5.7	1.5e-08	0.49	1.00	0.00	TRUE
7	GTEx	Breast Mammary Tissue (Male)	GOLGA6L4	0.23	0.07	lasso	2	0.12	8.3e-04	-5.4	-5.6	2.2e-08	0.49	0.07	0.31	TRUE
10	GTEx	Colon Transverse	AC103965.1	0.15	0.07	enet	33	0.06	7.1e-04	-4.8	-5.5	3.7e-08	0.45	0.11	0.45	TRUE
8	GTEx	Breast Mammary Tissue (Male)	AC103965.1	0.24	0.14	lasso	4	0.11	1.4e-03	3.2	-5.4	8.0e-08	0.53	0.07	0.57	TRUE
16	GTEx	Small Intestine Terminal Ileum	RP11-182J1.14	0.26	0.01	enet	27	0.12	1.3e-03	-6.9	5.3	1.0e-07	-0.41	0.05	0.24	TRUE
2	CommonMind	Brain Pre-frontal Cortex	LOC388152	0.14	0.14	enet	20	0.18	6.7e-22	3.3	-5.2	1.7e-07	0.48	1.00	0.00	TRUE
11	GTEx	Esophagus Mucosa	CSPG4P11	0.21	0.01	enet	28	0.08	3.7e-06	-4.8	-5.2	2.0e-07	0.49	0.70	0.21	TRUE
1	CommonMind	Brain Pre-frontal Cortex	ADAMTSL3	0.10	0.04	lasso	4	0.04	8.7e-06	-6.9	-6.2	6.2e-10	0.60	0.22	0.14	FALSE
18	GTEx	Whole Blood	GOLGA6L4	0.12	0.08	enet	16	0.11	2.1e-10	-4.8	-5.8	8.8e-09	0.49	0.86	0.14	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	GOLGA6L4	0.21	0.04	lasso	5	0.09	2.3e-03	-6.9	-5.6	2.0e-08	0.55	0.06	0.18	FALSE
4	GTEx	Brain Cerebellum	AC103965.1	0.13	0.02	enet	21	0.01	2.1e-01	3.3	-5.6	2.4e-08	0.49	0.08	0.43	FALSE
14	GTEx	Prostate	CSPG4P11	0.34	0.07	enet	13	0.18	2.3e-05	-1.0	-5.3	1.1e-07	0.36	0.07	0.67	FALSE
9	GTEx	Cells Transformed fibroblasts	AC103965.1	0.15	0.09	lasso	7	0.11	1.3e-08	3.3	-5.2	1.7e-07	0.50	0.75	0.24	FALSE
3	GTEx	Artery Tibial	SCAND2P	0.12	0.05	enet	16	0.08	8.7e-07	-2.9	-5.2	1.8e-07	0.39	0.64	0.07	FALSE
13	GTEx	Pancreas	RP11-182J1.16	0.08	-0.01	enet	11	-0.01	7.9e-01	-4.8	-5.2	2.0e-07	0.58	0.03	0.51	FALSE