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Traits
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Leg fat percentage (right)
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chr2:164,657,815-166,396,485
Best TWAS P=4.78e-12 · Best GWAS P=7.95e-17 conditioned to 0.00141
164.6M
164.8M
165M
165.2M
165.4M
165.6M
165.8M
166M
166.2M
166.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
GRB14
0.14
0.09
lasso
7
0.06
0.00016
6.7
-6.9
4.8e-12
-0.46
0.29
0.42
TRUE
2
GTEx
Thyroid
COBLL1
0.07
0.05
lasso
3
0.05
0.00015
-5.1
5.2
2.1e-07
0.59
0.57
0.25
TRUE