Best TWAS P=4.78e-12 · Best GWAS P=7.95e-17 conditioned to 0.00141
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | GRB14 | 0.14 | 0.09 | lasso | 7 | 0.06 | 0.00016 | 6.7 | -6.9 | 4.8e-12 | -0.46 | 0.29 | 0.42 | TRUE |
2 | GTEx | Thyroid | COBLL1 | 0.07 | 0.05 | lasso | 3 | 0.05 | 0.00015 | -5.1 | 5.2 | 2.1e-07 | 0.59 | 0.57 | 0.25 | TRUE |