[Hub]/) : Traits : Leg fat percentage (right) :

chr8:86,841,229-88,271,452

Best TWAS P=1.32e-09 · Best GWAS P=1.15e-09 conditioned to 0.0879

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CPNE3 0.17 0.07 blup 453 0.10 7.9e-12 4.1 -5.1 3.1e-07 0.59 0.20 0.80 FALSE
2 GTEx Artery Tibial RMDN1 0.18 0.08 lasso 9 0.10 1.8e-08 -5.8 5.7 9.9e-09 -0.95 0.01 0.99 FALSE
3 GTEx Brain Cerebellum NTAN1P2 0.19 0.14 enet 11 0.10 6.0e-04 -5.6 -5.5 3.4e-08 0.90 0.02 0.95 FALSE
4 GTEx Cells Transformed fibroblasts NTAN1P2 0.07 0.02 lasso 6 0.03 2.0e-03 -5.8 5.4 7.9e-08 -0.84 0.01 0.98 FALSE
5 GTEx Spleen RMDN1 0.46 0.20 enet 29 0.18 2.2e-05 -6.1 5.4 8.2e-08 -0.83 0.02 0.97 FALSE
6 GTEx Stomach RMDN1 0.15 0.05 lasso 6 0.06 1.2e-03 -6.1 5.5 3.1e-08 -0.88 0.01 0.97 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CPNE3 0.07 0.03 lasso 4 0.05 2.3e-06 -5.8 -5.3 1.4e-07 0.82 0.00 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma WWP1 0.03 0.01 blup 63 0.02 1.8e-03 -5.4 -5.8 7.7e-09 0.92 0.03 0.91 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma WWP1 0.05 0.01 enet 8 0.02 2.0e-02 5.1 -5.3 1.2e-07 0.80 0.02 0.59 FALSE
10 The Cancer Genome Atlas Soft Tissue Sarcoma FAM82B 0.07 0.00 blup 45 0.01 1.1e-01 -6.1 6.1 1.3e-09 -0.86 0.00 0.65 TRUE