Best TWAS P=1.32e-09 · Best GWAS P=1.15e-09 conditioned to 0.0879
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CPNE3 | 0.17 | 0.07 | blup | 453 | 0.10 | 7.9e-12 | 4.1 | -5.1 | 3.1e-07 | 0.59 | 0.20 | 0.80 | FALSE |
| 2 | GTEx | Artery Tibial | RMDN1 | 0.18 | 0.08 | lasso | 9 | 0.10 | 1.8e-08 | -5.8 | 5.7 | 9.9e-09 | -0.95 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Brain Cerebellum | NTAN1P2 | 0.19 | 0.14 | enet | 11 | 0.10 | 6.0e-04 | -5.6 | -5.5 | 3.4e-08 | 0.90 | 0.02 | 0.95 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | NTAN1P2 | 0.07 | 0.02 | lasso | 6 | 0.03 | 2.0e-03 | -5.8 | 5.4 | 7.9e-08 | -0.84 | 0.01 | 0.98 | FALSE |
| 5 | GTEx | Spleen | RMDN1 | 0.46 | 0.20 | enet | 29 | 0.18 | 2.2e-05 | -6.1 | 5.4 | 8.2e-08 | -0.83 | 0.02 | 0.97 | FALSE |
| 6 | GTEx | Stomach | RMDN1 | 0.15 | 0.05 | lasso | 6 | 0.06 | 1.2e-03 | -6.1 | 5.5 | 3.1e-08 | -0.88 | 0.01 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CPNE3 | 0.07 | 0.03 | lasso | 4 | 0.05 | 2.3e-06 | -5.8 | -5.3 | 1.4e-07 | 0.82 | 0.00 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | WWP1 | 0.03 | 0.01 | blup | 63 | 0.02 | 1.8e-03 | -5.4 | -5.8 | 7.7e-09 | 0.92 | 0.03 | 0.91 | FALSE |
| 9 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | WWP1 | 0.05 | 0.01 | enet | 8 | 0.02 | 2.0e-02 | 5.1 | -5.3 | 1.2e-07 | 0.80 | 0.02 | 0.59 | FALSE |
| 10 | The Cancer Genome Atlas | Soft Tissue Sarcoma | FAM82B | 0.07 | 0.00 | blup | 45 | 0.01 | 1.1e-01 | -6.1 | 6.1 | 1.3e-09 | -0.86 | 0.00 | 0.65 | TRUE |