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chr9:14,857,740-16,758,776

Best TWAS P=6.57e-30 · Best GWAS P=1.21e-26 conditioned to 0.097

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-10.6	-11.4	6.6e-30	0.87	0.09	0.89	TRUE
5	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-10.3	-10.8	4.7e-27	0.95	0.04	0.95	FALSE
11	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-10.3	-10.3	1.0e-24	0.95	0.10	0.90	FALSE
3	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	9.1	-10.2	1.8e-24	0.92	0.06	0.94	FALSE
13	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	9.3	-9.8	1.4e-22	0.87	0.22	0.71	FALSE
6	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-8.8	-9.7	3.2e-22	0.89	0.08	0.87	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	9.3	-9.4	3.9e-21	0.80	0.83	0.17	FALSE
7	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	9.5	-9.1	9.8e-20	0.81	0.08	0.85	FALSE
8	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-10.6	-9.0	1.9e-19	0.90	0.06	0.80	FALSE
12	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	8.9	8.6	1.1e-17	-0.82	0.18	0.46	FALSE
16	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	9.5	-8.5	1.5e-17	0.77	0.19	0.60	FALSE
10	GTEx	Lung	CCDC171	0.13	0.03	enet	9	0.01	5.0e-02	6.5	-8.2	2.2e-16	0.65	0.44	0.30	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf93	0.06	0.05	lasso	3	0.03	5.3e-03	8.7	-7.4	1.1e-13	0.67	0.12	0.33	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CCDC171	0.14	0.09	enet	13	0.12	1.9e-10	8.9	-6.8	1.0e-11	0.61	1.00	0.00	FALSE
2	GTEx	Artery Tibial	CCDC171	0.10	0.09	enet	9	0.12	7.2e-10	5.7	-6.5	6.8e-11	0.57	0.91	0.08	FALSE
9	GTEx	Breast Mammary Tissue	CCDC171	0.21	0.01	lasso	5	0.03	1.5e-02	8.6	-5.7	1.0e-08	0.52	0.37	0.19	FALSE
1	GTEx	Artery Aorta	CCDC171	0.18	0.05	lasso	5	0.08	2.2e-05	-3.4	-5.5	3.4e-08	0.30	0.34	0.06	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CCDC171	0.20	0.04	enet	45	0.06	4.9e-04	9.4	-5.3	1.0e-07	0.37	0.71	0.16	FALSE