[Hub]/) : Traits : Leg fat percentage (right) :

chr9:14,857,740-16,758,776

Best TWAS P=6.57e-30 · Best GWAS P=1.21e-26 conditioned to 0.097

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CCDC171 0.18 0.05 lasso 5 0.08 2.2e-05 -3.4 -5.5 3.4e-08 0.30 0.34 0.06 FALSE
2 GTEx Artery Tibial CCDC171 0.10 0.09 enet 9 0.12 7.2e-10 5.7 -6.5 6.8e-11 0.57 0.91 0.08 FALSE
3 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 9.1 -10.2 1.8e-24 0.92 0.06 0.94 FALSE
4 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 -10.6 -11.4 6.6e-30 0.87 0.09 0.89 TRUE
5 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 -10.3 -10.8 4.7e-27 0.95 0.04 0.95 FALSE
6 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 -8.8 -9.7 3.2e-22 0.89 0.08 0.87 FALSE
7 GTEx Brain Frontal Cortex BA9 CCDC171 0.27 0.18 enet 10 0.19 8.3e-06 9.5 -9.1 9.8e-20 0.81 0.08 0.85 FALSE
8 GTEx Brain Hypothalamus CCDC171 0.32 0.17 enet 6 0.09 4.0e-03 -10.6 -9.0 1.9e-19 0.90 0.06 0.80 FALSE
9 GTEx Breast Mammary Tissue CCDC171 0.21 0.01 lasso 5 0.03 1.5e-02 8.6 -5.7 1.0e-08 0.52 0.37 0.19 FALSE
10 GTEx Lung CCDC171 0.13 0.03 enet 9 0.01 5.0e-02 6.5 -8.2 2.2e-16 0.65 0.44 0.30 FALSE
11 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 -10.3 -10.3 1.0e-24 0.95 0.10 0.90 FALSE
12 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 8.9 8.6 1.1e-17 -0.82 0.18 0.46 FALSE
13 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 9.3 -9.8 1.4e-22 0.87 0.22 0.71 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic CCDC171 0.20 0.04 enet 45 0.06 4.9e-04 9.4 -5.3 1.0e-07 0.37 0.71 0.16 FALSE
15 GTEx Skin Sun Exposed Lower leg CCDC171 0.14 0.09 enet 13 0.12 1.9e-10 8.9 -6.8 1.0e-11 0.61 1.00 0.00 FALSE
16 METSIM Adipose CCDC171 0.03 0.00 blup 828 0.01 4.0e-02 9.5 -8.5 1.5e-17 0.77 0.19 0.60 FALSE
17 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 9.3 -9.4 3.9e-21 0.80 0.83 0.17 FALSE
18 The Cancer Genome Atlas Soft Tissue Sarcoma C9orf93 0.06 0.05 lasso 3 0.03 5.3e-03 8.7 -7.4 1.1e-13 0.67 0.12 0.33 FALSE