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Leg fat percentage (right)
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chr10:71,736,472-73,755,778
Best TWAS P=1.52e-08 · Best GWAS P=1.46e-11 conditioned to 0.0139
72M
72.5M
73M
73.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
PCBD1
0.19
0.01
lasso
6
0.01
3.0e-02
-3.9
5.7
1.5e-08
0.44
0.08
0.42
TRUE
4
METSIM
Adipose
UNC5B
0.06
0.00
blup
805
0.01
3.3e-02
-3.1
-5.4
8.7e-08
-0.06
0.14
0.02
TRUE
5
ROSMAP
Brain Pre-frontal Cortex
ADAMTS14
0.38
0.35
bslmm
710
0.47
3.9e-67
6.6
5.3
1.5e-07
0.86
0.00
1.00
TRUE
3
GTEx
Esophagus Muscularis
PCBD1
0.16
0.04
lasso
3
0.07
4.3e-05
-2.9
5.3
1.0e-07
0.26
0.50
0.03
FALSE
1
CommonMind
Brain Pre-frontal Cortex
ADAMTS14
0.28
0.24
bslmm
733
0.35
7.9e-44
-1.8
5.2
1.9e-07
0.81
0.12
0.88
FALSE