Best TWAS P=1.52e-08 · Best GWAS P=1.46e-11 conditioned to 0.0139
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADAMTS14 | 0.28 | 0.24 | bslmm | 733 | 0.35 | 7.9e-44 | -1.8 | 5.2 | 1.9e-07 | 0.81 | 0.12 | 0.88 | FALSE |
| 2 | GTEx | Artery Tibial | PCBD1 | 0.19 | 0.01 | lasso | 6 | 0.01 | 3.0e-02 | -3.9 | 5.7 | 1.5e-08 | 0.44 | 0.08 | 0.42 | TRUE |
| 3 | GTEx | Esophagus Muscularis | PCBD1 | 0.16 | 0.04 | lasso | 3 | 0.07 | 4.3e-05 | -2.9 | 5.3 | 1.0e-07 | 0.26 | 0.50 | 0.03 | FALSE |
| 4 | METSIM | Adipose | UNC5B | 0.06 | 0.00 | blup | 805 | 0.01 | 3.3e-02 | -3.1 | -5.4 | 8.7e-08 | -0.06 | 0.14 | 0.02 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | ADAMTS14 | 0.38 | 0.35 | bslmm | 710 | 0.47 | 3.9e-67 | 6.6 | 5.3 | 1.5e-07 | 0.86 | 0.00 | 1.00 | TRUE |