TWAS
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Models
Genes
Traits
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Traits
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Leg fat percentage (right)
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chr10:86,661,963-88,819,133
Best TWAS P=7.01e-08 · Best GWAS P=1.05e-08 conditioned to 0.0285
87M
87.5M
88M
88.5M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
GRID1
0.09
0.04
lasso
9
0.03
2.1e-07
-5.1
-5.4
7.0e-08
0.84
0.06
0.94
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
GRID1
0.07
0.03
lasso
4
0.02
9.7e-04
-5.1
-5.2
2.0e-07
0.84
0.02
0.96
FALSE
1
GTEx
Artery Tibial
GRID1
0.16
0.08
enet
32
0.06
2.5e-05
-5.1
-5.1
2.7e-07
0.66
0.02
0.98
FALSE