Best TWAS P=7.01e-08 · Best GWAS P=1.05e-08 conditioned to 0.0285
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | GRID1 | 0.16 | 0.08 | enet | 32 | 0.06 | 2.5e-05 | -5.1 | -5.1 | 2.7e-07 | 0.66 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRID1 | 0.09 | 0.04 | lasso | 9 | 0.03 | 2.1e-07 | -5.1 | -5.4 | 7.0e-08 | 0.84 | 0.06 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GRID1 | 0.07 | 0.03 | lasso | 4 | 0.02 | 9.7e-04 | -5.1 | -5.2 | 2.0e-07 | 0.84 | 0.02 | 0.96 | FALSE |