Best TWAS P=5.45e-08 · Best GWAS P=1.98e-13 conditioned to 6.45e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pancreas | NOC3L | 0.21 | 0.14 | lasso | 6 | 0.17 | 1.5e-07 | -3.8 | -5.2 | 2.4e-07 | 0.43 | 0.43 | 0.08 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TBC1D12 | 0.04 | 0.04 | blup | 63 | 0.03 | 3.9e-04 | -4.2 | -5.4 | 5.4e-08 | 0.12 | 0.11 | 0.77 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | HELLS | 0.05 | 0.02 | blup | 47 | 0.03 | 9.6e-04 | -4.1 | -5.2 | 2.4e-07 | 0.14 | 0.08 | 0.79 | FALSE |