TWAS
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Usage
Models
Genes
Traits
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Traits
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Leg fat percentage (right)
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chr10:95,379,543-96,818,402
Best TWAS P=5.45e-08 · Best GWAS P=1.98e-13 conditioned to 6.45e-07
95.4M
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
TBC1D12
0.04
0.04
blup
63
0.03
3.9e-04
-4.2
-5.4
5.4e-08
0.12
0.11
0.77
TRUE
1
GTEx
Pancreas
NOC3L
0.21
0.14
lasso
6
0.17
1.5e-07
-3.8
-5.2
2.4e-07
0.43
0.43
0.08
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
HELLS
0.05
0.02
blup
47
0.03
9.6e-04
-4.1
-5.2
2.4e-07
0.14
0.08
0.79
FALSE