Best TWAS P=1.09e-14 · Best GWAS P=2.56e-20 conditioned to 3.08e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -5.7 | 6.2 | 4.5e-10 | -0.66 | 0.72 | 0.10 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.1 | 7.7 | 1.1e-14 | -0.48 | 0.98 | 0.02 | TRUE |