[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr1:45,100,098-51,180,660

Best TWAS P=5.04e-12 · Best GWAS P=9.34e-15 conditioned to 0.000251

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MUTYH	0.04	0.00	enet	23	0.00	8.5e-01	-2.9	5.3	1.2e-07	-0.01	0.08	0.56	FALSE
2	GTEx	Adipose Subcutaneous	RP11-767N6.2	0.03	0.03	enet	6	0.04	3.0e-04	-4.1	-5.7	9.2e-09	-0.04	0.11	0.70	FALSE
3	GTEx	Adipose Visceral Omentum	PIK3R3	0.07	0.02	lasso	3	0.04	4.6e-03	-5.1	-5.2	1.7e-07	-0.01	0.15	0.71	FALSE
4	GTEx	Breast Mammary Tissue	GPBP1L1	0.06	0.02	lasso	5	0.00	2.4e-01	-5.3	5.4	5.3e-08	0.01	0.08	0.71	FALSE
5	GTEx	Cells Transformed fibroblasts	IPP	0.04	0.08	lasso	1	0.08	2.3e-06	-5.3	5.3	1.1e-07	0.04	0.08	0.92	FALSE
6	GTEx	Colon Transverse	GPBP1L1	0.06	0.01	lasso	6	0.01	8.3e-02	-5.4	5.4	6.4e-08	0.04	0.09	0.77	FALSE
7	GTEx	Esophagus Mucosa	GPBP1L1	0.04	0.02	lasso	3	0.02	1.5e-02	-5.4	5.4	6.6e-08	0.04	0.08	0.67	FALSE
8	GTEx	Esophagus Muscularis	CCDC17	0.04	0.04	lasso	6	0.01	9.1e-02	-5.3	5.4	7.0e-08	0.04	0.06	0.88	FALSE
9	GTEx	Lung	GPBP1L1	0.04	0.02	enet	14	0.02	5.8e-03	-5.4	5.2	1.9e-07	0.05	0.06	0.90	FALSE
10	GTEx	Muscle Skeletal	GPBP1L1	0.03	0.02	enet	19	0.03	7.2e-04	-5.6	5.5	3.8e-08	0.04	0.05	0.91	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	CCDC17	0.10	0.13	lasso	6	0.13	9.6e-08	-5.3	5.3	1.4e-07	0.04	0.08	0.92	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	GPBP1L1	0.09	0.02	enet	11	0.02	3.5e-02	-5.5	5.4	7.4e-08	0.03	0.06	0.93	FALSE
13	GTEx	Stomach	RP11-767N6.7	0.08	0.03	enet	16	0.05	1.3e-03	3.6	5.8	7.9e-09	0.02	0.27	0.32	TRUE
14	GTEx	Testis	PIK3R3	0.08	0.05	enet	7	0.06	1.5e-03	-5.3	5.5	4.0e-08	0.05	0.08	0.86	FALSE
15	GTEx	Testis	IPP	0.05	0.06	enet	8	0.03	1.4e-02	-5.4	-5.7	1.0e-08	-0.03	0.07	0.80	FALSE
16	GTEx	Thyroid	MAST2	0.06	0.05	lasso	4	0.04	4.9e-04	-5.2	5.3	1.4e-07	0.01	0.19	0.76	FALSE
17	GTEx	Thyroid	GPBP1L1	0.05	0.06	enet	6	0.07	7.9e-06	-4.7	5.3	1.1e-07	0.04	0.15	0.84	FALSE
18	GTEx	Whole Blood	MAST2	0.03	0.02	lasso	3	0.02	2.9e-03	-5.6	5.6	2.7e-08	0.05	0.06	0.88	FALSE
19	METSIM	Adipose	AGBL4	0.02	0.02	lasso	5	0.02	1.3e-03	6.8	-6.9	5.0e-12	-0.85	0.16	0.82	TRUE
20	ROSMAP	Brain Pre-frontal Cortex	IPP	0.08	0.15	lasso	9	0.14	5.0e-18	-5.7	5.6	1.9e-08	0.04	0.06	0.94	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	RPS15AP10	0.03	0.05	blup	283	0.04	8.0e-06	-5.6	-5.7	1.5e-08	-0.03	0.05	0.95	FALSE
22	YFS	Blood	CCDC17	0.04	0.02	lasso	8	0.02	6.8e-08	-5.4	5.5	2.9e-08	0.04	0.07	0.93	FALSE
23	YFS	Blood	IPP	0.10	0.11	lasso	15	0.12	4.6e-36	-5.7	5.8	8.1e-09	0.04	0.04	0.96	FALSE
24	YFS	Blood	TAL1	0.03	0.02	bslmm	402	0.02	2.6e-06	5.4	-5.2	2.1e-07	0.03	0.01	0.99	TRUE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	GPBP1L1	0.01	0.02	lasso	2	0.02	1.2e-04	-5.4	5.4	8.0e-08	0.04	0.04	0.91	FALSE
26	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GPBP1L1	0.05	0.05	blup	51	0.06	1.0e-03	-5.7	5.4	6.1e-08	0.04	0.04	0.79	FALSE
27	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPBP1L1	0.03	0.04	lasso	1	0.03	8.0e-05	-5.3	5.3	1.1e-07	0.04	0.04	0.94	FALSE
28	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GPBP1L1	0.07	0.10	lasso	3	0.09	6.3e-06	-5.4	5.4	7.7e-08	0.04	0.04	0.96	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPBP1L1	0.04	0.04	blup	50	0.04	2.9e-05	-5.4	5.6	2.6e-08	0.04	0.04	0.94	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	IPP	0.04	0.04	blup	47	0.04	1.4e-03	-5.3	5.6	2.2e-08	0.04	0.03	0.79	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	GPBP1L1	0.11	0.06	lasso	3	0.06	1.6e-06	-5.4	5.4	8.1e-08	0.04	0.06	0.93	FALSE