[Hub]/) : Traits : Leg fat-free mass (right) : →

chr1:752,566-3,191,909

Best TWAS P=4.21e-10 · Best GWAS P=9.41e-09 conditioned to 0.00368

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	4.5	6.2	4.2e-10	-0.01	0.34	0.62	TRUE
6	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-5.7	6.1	1.3e-09	0.28	0.02	0.61	TRUE
8	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	4.6	5.6	2.6e-08	0.00	0.32	0.67	TRUE
4	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-2.3	-5.2	1.8e-07	-0.27	0.14	0.15	TRUE
3	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-4.9	-6.0	2.5e-09	-0.11	0.21	0.53	FALSE
11	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.2	-5.5	4.3e-08	-0.23	0.06	0.80	FALSE
5	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-5.2	-5.3	9.6e-08	-0.27	0.03	0.63	FALSE
10	GTEx	Lung	AL590822.2	0.09	0.00	lasso	3	0.00	2.0e-01	4.9	5.3	1.1e-07	0.06	0.08	0.17	FALSE
13	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.2	5.3	1.4e-07	0.26	0.13	0.87	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC35E2	0.35	0.15	enet	24	0.17	1.0e-20	-5.7	5.2	1.5e-07	0.32	0.01	0.99	FALSE
16	GTEx	Thyroid	PRKCZ	0.16	0.03	lasso	4	0.08	1.9e-06	-4.8	-5.2	1.5e-07	0.04	0.24	0.18	FALSE
14	GTEx	Nerve Tibial	RP11-181G12.2	0.24	0.22	lasso	5	0.21	3.7e-15	-4.9	5.2	2.1e-07	0.02	0.27	0.73	FALSE
15	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.1	5.2	2.2e-07	0.26	0.07	0.93	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-3.8	5.2	2.2e-07	0.22	0.95	0.04	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	5.0	5.2	2.3e-07	0.01	0.09	0.23	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RER1	0.06	0.00	blup	359	0.01	8.1e-03	1.5	-5.2	2.4e-07	-0.01	0.04	0.11	FALSE
9	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	4.5	-5.2	2.5e-07	-0.27	0.04	0.87	FALSE
12	GTEx	Muscle Skeletal	C1orf86	0.20	0.16	lasso	4	0.15	8.0e-15	-4.9	-5.1	3.1e-07	-0.02	0.27	0.73	FALSE