Best TWAS P=3.11e-08 · Best GWAS P=8.68e-10 conditioned to 0.103
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | RP11-152H18.3 | 0.41 | 0.04 | enet | 25 | 0.11 | 7.6e-04 | 3.0 | -5.1 | 2.8e-07 | 0.03 | 0.05 | 0.51 | TRUE |
| 2 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | 4.7 | 5.5 | 3.1e-08 | -0.86 | 0.05 | 0.71 | TRUE |
| 3 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | 4.7 | -5.3 | 1.3e-07 | 0.88 | 0.16 | 0.84 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | SBF2-AS1 | 0.03 | 0.00 | bslmm | 362 | 0.01 | 4.4e-03 | -1.7 | 5.3 | 9.8e-08 | -0.59 | 0.04 | 0.61 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF143 | 0.02 | 0.02 | lasso | 2 | 0.02 | 4.5e-03 | 5.4 | -5.5 | 3.7e-08 | 0.07 | 0.01 | 0.93 | TRUE |