TWAS
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Models
Genes
Traits
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Traits
:
Leg fat-free mass (right)
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chr14:23,319,172-24,016,366
Best TWAS P=2.4e-08 · Best GWAS P=5.87e-14 conditioned to 3.2e-09
23.3M
23.4M
23.5M
23.6M
23.7M
23.8M
23.9M
24M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
HOMEZ
0.19
0.01
blup
41
0.05
6.0e-03
3.1
5.6
2.4e-08
-0.54
0.01
0.39
TRUE
3
The Cancer Genome Atlas
Stomach Adenocarcinoma
C14orf119
0.08
0.07
lasso
1
0.05
8.8e-05
5.3
-5.3
1.4e-07
-0.09
0.00
0.99
TRUE
1
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
C14orf119
0.03
0.03
enet
5
0.03
5.8e-04
5.3
-5.2
1.9e-07
-0.09
0.00
0.98
FALSE