[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr14:24,098,631-25,546,115

Best TWAS P=1.78e-12 · Best GWAS P=1.09e-11 conditioned to 0.792

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Atrial Appendage ADCY4 0.28 0.14 lasso 4 0.10 2.1e-05 6.4 5.4 7.3e-08 0.48 0.03 0.94 TRUE
2 GTEx Spleen NFATC4 0.45 0.00 enet 24 0.00 2.5e-01 4.1 -5.2 1.6e-07 -0.22 0.07 0.06 TRUE
3 GTEx Thyroid ADCY4 0.13 0.13 lasso 6 0.09 1.0e-07 4.2 5.4 6.0e-08 0.51 0.25 0.75 FALSE
4 METSIM Adipose ADCY4 0.07 0.03 lasso 5 0.03 2.2e-05 6.4 7.1 1.8e-12 0.71 0.03 0.97 TRUE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma ADCY4 0.03 0.01 blup 75 0.03 1.1e-03 4.2 5.5 4.1e-08 0.71 0.04 0.76 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma ADCY4 0.07 0.02 lasso 4 0.03 4.7e-03 4.5 5.5 3.9e-08 0.70 0.03 0.76 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY4 0.06 0.06 lasso 6 0.09 3.0e-10 6.2 6.9 4.9e-12 0.75 0.03 0.97 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma ADCY4 0.07 0.09 lasso 3 0.08 4.4e-10 4.6 5.9 2.8e-09 0.73 0.70 0.30 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LTB4R 0.16 0.05 blup 73 0.08 4.9e-04 3.0 -5.2 1.5e-07 -0.70 0.03 0.53 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R 0.04 0.01 blup 73 0.01 4.2e-02 5.9 -5.3 1.4e-07 -0.63 0.01 0.46 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R2 0.04 0.04 lasso 1 0.02 2.5e-02 5.9 -5.9 2.8e-09 -0.70 0.03 0.63 FALSE