[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr14:24,098,631-25,546,115

Best TWAS P=1.78e-12 · Best GWAS P=1.09e-11 conditioned to 0.792

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	6.4	7.1	1.8e-12	0.71	0.03	0.97	TRUE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	4.5	5.5	3.9e-08	0.70	0.03	0.76	TRUE
1	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	6.4	5.4	7.3e-08	0.48	0.03	0.94	TRUE
2	GTEx	Spleen	NFATC4	0.45	0.00	enet	24	0.00	2.5e-01	4.1	-5.2	1.6e-07	-0.22	0.07	0.06	TRUE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	6.2	6.9	4.9e-12	0.75	0.03	0.97	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	4.6	5.9	2.8e-09	0.73	0.70	0.30	FALSE
11	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	5.9	-5.9	2.8e-09	-0.70	0.03	0.63	FALSE
5	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	4.2	5.5	4.1e-08	0.71	0.04	0.76	FALSE
3	GTEx	Thyroid	ADCY4	0.13	0.13	lasso	6	0.09	1.0e-07	4.2	5.4	6.0e-08	0.51	0.25	0.75	FALSE
10	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R	0.04	0.01	blup	73	0.01	4.2e-02	5.9	-5.3	1.4e-07	-0.63	0.01	0.46	FALSE
9	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LTB4R	0.16	0.05	blup	73	0.08	4.9e-04	3.0	-5.2	1.5e-07	-0.70	0.03	0.53	FALSE