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chr17:39,420,932-41,538,783

Best TWAS P=2.72e-08 · Best GWAS P=1.04e-07 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Colon Adenocarcinoma	CNTNAP1	0.06	0.05	blup	27	0.03	7.3e-03	-5.3	5.6	2.7e-08	-0.96	0.01	0.95	TRUE
9	METSIM	Adipose	CNP	0.04	0.02	blup	367	0.03	8.7e-05	3.4	-5.2	1.6e-07	0.08	0.14	0.43	TRUE
7	GTEx	Skin Not Sun Exposed Suprapubic	TUBG1	0.11	0.01	lasso	6	0.00	1.7e-01	4.7	-5.5	3.0e-08	0.88	0.03	0.76	FALSE
4	GTEx	Breast Mammary Tissue	TUBG2	0.15	0.06	enet	18	0.08	4.5e-05	-5.0	-5.5	3.3e-08	0.92	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MLX	0.03	0.03	enet	12	0.02	6.5e-04	-5.3	-5.5	3.9e-08	0.93	0.02	0.97	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	CNTNAP1	0.04	0.03	blup	27	0.05	2.7e-05	-5.2	5.4	6.2e-08	-0.90	0.01	0.98	FALSE
2	GTEx	Adipose Subcutaneous	HSD17B1P1	0.06	0.09	enet	6	0.09	4.0e-08	-5.0	-5.4	7.4e-08	0.91	0.04	0.96	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	CNTNAP1	0.06	0.04	blup	27	0.04	8.9e-05	-5.2	5.3	1.0e-07	-0.93	0.00	0.99	FALSE
8	GTEx	Skin Sun Exposed Lower leg	NAGLU	0.08	0.06	enet	9	0.09	5.8e-08	4.0	-5.3	1.4e-07	0.82	0.03	0.97	FALSE
3	GTEx	Brain Cerebellum	HSD17B1P1	0.17	0.16	lasso	4	0.20	1.7e-06	-5.3	-5.2	1.5e-07	0.94	0.05	0.93	FALSE
10	METSIM	Adipose	TUBG2	0.08	0.09	lasso	6	0.09	5.2e-13	4.6	-5.2	1.7e-07	0.85	0.03	0.97	FALSE
12	The Cancer Genome Atlas	Lung Adenocarcinoma	CNTNAP1	0.06	0.05	lasso	1	0.04	6.8e-06	-5.2	5.2	2.4e-07	-0.99	0.00	0.99	FALSE
6	GTEx	Colon Sigmoid	TUBG2	0.16	0.04	lasso	5	0.05	6.7e-03	-5.3	-5.1	2.8e-07	0.97	0.03	0.89	FALSE
5	GTEx	Breast Mammary Tissue	CNTNAP1	0.06	0.03	lasso	2	0.05	9.9e-04	-5.1	5.1	3.0e-07	-0.97	0.02	0.93	FALSE