[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr17:39,420,932-41,538,783

Best TWAS P=2.72e-08 · Best GWAS P=1.04e-07 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MLX 0.03 0.03 enet 12 0.02 6.5e-04 -5.3 -5.5 3.9e-08 0.93 0.02 0.97 FALSE
2 GTEx Adipose Subcutaneous HSD17B1P1 0.06 0.09 enet 6 0.09 4.0e-08 -5.0 -5.4 7.4e-08 0.91 0.04 0.96 FALSE
3 GTEx Brain Cerebellum HSD17B1P1 0.17 0.16 lasso 4 0.20 1.7e-06 -5.3 -5.2 1.5e-07 0.94 0.05 0.93 FALSE
4 GTEx Breast Mammary Tissue TUBG2 0.15 0.06 enet 18 0.08 4.5e-05 -5.0 -5.5 3.3e-08 0.92 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue CNTNAP1 0.06 0.03 lasso 2 0.05 9.9e-04 -5.1 5.1 3.0e-07 -0.97 0.02 0.93 FALSE
6 GTEx Colon Sigmoid TUBG2 0.16 0.04 lasso 5 0.05 6.7e-03 -5.3 -5.1 2.8e-07 0.97 0.03 0.89 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic TUBG1 0.11 0.01 lasso 6 0.00 1.7e-01 4.7 -5.5 3.0e-08 0.88 0.03 0.76 FALSE
8 GTEx Skin Sun Exposed Lower leg NAGLU 0.08 0.06 enet 9 0.09 5.8e-08 4.0 -5.3 1.4e-07 0.82 0.03 0.97 FALSE
9 METSIM Adipose CNP 0.04 0.02 blup 367 0.03 8.7e-05 3.4 -5.2 1.6e-07 0.08 0.14 0.43 TRUE
10 METSIM Adipose TUBG2 0.08 0.09 lasso 6 0.09 5.2e-13 4.6 -5.2 1.7e-07 0.85 0.03 0.97 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma CNTNAP1 0.06 0.05 blup 27 0.03 7.3e-03 -5.3 5.6 2.7e-08 -0.96 0.01 0.95 TRUE
12 The Cancer Genome Atlas Lung Adenocarcinoma CNTNAP1 0.06 0.05 lasso 1 0.04 6.8e-06 -5.2 5.2 2.4e-07 -0.99 0.00 0.99 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma CNTNAP1 0.06 0.04 blup 27 0.04 8.9e-05 -5.2 5.3 1.0e-07 -0.93 0.00 0.99 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma CNTNAP1 0.04 0.03 blup 27 0.05 2.7e-05 -5.2 5.4 6.2e-08 -0.90 0.01 0.98 FALSE