[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr4:85,698,680-88,430,396

Best TWAS P=2.13e-09 · Best GWAS P=3.26e-09 conditioned to 0.716

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Colon Sigmoid	MAPK10	0.25	0.11	lasso	8	0.07	1.6e-03	5.8	-6.0	2.1e-09	-0.89	0.02	0.96	TRUE
6	GTEx	Artery Tibial	RP13-514E23.2	0.22	0.16	enet	10	0.18	1.2e-13	-5.8	-5.8	7.0e-09	-0.07	0.01	0.99	TRUE
8	GTEx	Thyroid	PTPN13	0.41	0.31	lasso	6	0.30	3.2e-23	5.9	5.8	5.7e-09	0.99	0.01	0.99	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	PTPN13	0.09	0.03	blup	409	0.07	4.7e-09	5.1	-5.7	1.2e-08	-0.53	0.34	0.66	FALSE
2	GTEx	Artery Aorta	MAPK10	0.15	0.17	enet	16	0.17	1.4e-09	5.8	-5.7	1.5e-08	-0.96	0.01	0.99	FALSE
4	GTEx	Artery Aorta	RP13-514E23.2	0.26	0.09	lasso	6	0.10	2.2e-06	-5.8	-5.6	2.2e-08	-0.08	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PTPN13	0.13	0.18	bslmm	418	0.18	6.8e-22	5.1	-5.5	3.9e-08	-0.53	0.37	0.63	FALSE
5	GTEx	Artery Tibial	ARHGAP24	0.26	0.19	enet	14	0.21	2.7e-16	-5.8	-5.5	4.6e-08	-0.05	0.01	0.99	FALSE
3	GTEx	Artery Aorta	ARHGAP24	0.24	0.13	enet	8	0.14	2.2e-08	-4.2	-5.3	1.0e-07	-0.10	0.03	0.96	FALSE