[Hub]/) : Traits : Leg predicted mass (right) :

chr6:151,477,414-153,695,725

Best TWAS P=2.41e-08 · Best GWAS P=1.3e-20 conditioned to 6.21e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 ROSMAP Brain Pre-frontal Cortex SYNE1 0.12 0.01 blup 875 0.05 6.9e-07 1.3 5.3 1.4e-07 0.26 0.63 0.08 TRUE
2 The Cancer Genome Atlas Breast Invasive Carcinoma RGS17 0.02 0.02 enet 5 0.02 1.8e-04 5.0 -5.1 2.7e-07 0.02 0.00 0.98 TRUE
3 The Cancer Genome Atlas Breast Invasive Carcinoma RMND1 0.02 0.00 blup 57 0.01 3.1e-03 4.2 -5.3 1.2e-07 -0.02 0.00 0.60 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RMND1 0.16 0.10 lasso 7 0.12 1.6e-06 4.5 -5.5 4.5e-08 -0.02 0.02 0.98 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RMND1 0.07 0.06 blup 58 0.09 1.4e-10 4.5 -5.2 1.9e-07 0.01 0.22 0.78 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma C6orf211 0.05 0.03 lasso 3 0.04 6.3e-05 4.7 -5.1 3.1e-07 -0.01 0.01 0.97 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma RMND1 0.05 0.06 lasso 2 0.07 4.3e-08 5.9 -5.6 2.4e-08 -0.04 0.00 1.00 TRUE
8 The Cancer Genome Atlas Stomach Adenocarcinoma RMND1 0.06 0.04 blup 57 0.06 4.9e-05 4.0 -5.5 3.6e-08 -0.03 0.03 0.88 FALSE