Hub : Genes

C6orf211

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Brain Lower Grade Glioma 0.0528 0.028 2.3e-05 0.033 0.03 0.030 NA 0.035 9.8e-05 2.0e-04 0.00022 NA 6.3e-05
2 TCGA Thyroid Carcinoma 0.0690 0.032 8.5e-05 -0.001 0.04 0.026 NA 0.009 4.2e-01 8.6e-05 0.00140 NA 4.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.2 0.3 0.5 0.7 0.2
Bipolar Disorder or Schizophrenia 0.5 1.3 2.2 -0.5 1.5
Depressed Affect (Nagel 2018) 0.1 0.1 0.1 -0.3 0.4
Depression (Nagel 2018) 3.0 4.4 5.0 -2.2 2.0
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.5 0.3 0.7
Neuroticism (Nagel 2018) 0.0 0.1 0.2 -0.0 0.4
Schizophrenia (2018) 1.1 2.3 3.0 -1.2 1.7
Schizophrenia vs Biploar Disorder 0.3 0.3 0.6 -0.3 0.8
Worry (Nagel 2018) 0.1 0.2 0.3 -0.5 0.4
Alzheimer’s Disease (in mother) 3.0 3.5 5.5 -2.4 1.2
Alzheimer’s Disease (in father) 0.2 0.2 0.3 0.4 0.5
Alzheimer’s Disease (including proxy) 0.3 0.4 0.7 -0.8 0.4
Crohns Disease (2017) 0.9 2.0 3.3 1.8 -0.9
Irritable Bowel Disease (IBD) 1.3 3.2 4.9 2.2 -1.2
Ulcerative Colitis (UC) 1.0 1.8 3.0 1.7 -0.8
Major Depression (MDD) 0.2 0.3 0.5 -0.3 -0.7
Reaction Time 0.6 1.1 1.1 -1.0 1.0
Verbal and Numeric Reasoning (VNR) 0.2 0.4 0.7 0.8 -0.3
Breast Cancer 1.3 3.0 4.5 -1.3 -2.1
Ovarian Cancer 0.4 0.6 0.7 -0.7 0.8
Prostate Cancer 0.0 0.0 0.0 0.0 0.0
Age at First Birth 2.7 3.9 4.6 2.1 -1.8
Bipolar Disorder (2011) 0.7 0.7 0.7 0.8 0.9
Body Mass Index (BMI) (2010) 0.7 0.9 0.9 -0.9 -1.0
Coronary Artery Disease (CAD) 0.2 0.3 0.4 -0.3 0.6
Crohns Disease (2012) 1.1 1.7 2.7 1.7 -0.8
Mean Putamen Volume 0.9 1.0 1.6 -1.3 0.6
Fasting Glucose 0.3 0.3 0.5 -0.7 -0.4
HbA1C 0.1 0.1 0.2 0.4 -0.1
HDL Cholesterol 0.5 0.9 1.7 0.3 1.3
LDL Cholesterol 0.2 0.3 0.6 -0.2 -0.8
Lupus 0.5 0.7 1.2 0.4 -1.1
Neuroticism (2016) 0.1 0.1 0.2 0.1 0.5
Primary Biliary Cirrhosis 0.2 0.3 0.6 -0.3 0.8
Rheumatoid Arthritis 2.5 3.4 5.4 1.2 -2.3
Schizophrenia (2014) 0.8 1.8 2.9 -0.8 1.7
Triglycerides 0.3 0.5 0.8 -0.4 -0.9
Type 2 Diabetes (T2D) (2012) 0.3 0.3 0.5 0.7 -0.3
Ulcerative Colitis 0.3 0.5 0.6 0.8 -0.6
Blood Eosinophil Count 1.7 12.7 21.3 4.6 -2.0
Blood Platelet Count 0.6 6.8 9.2 2.1 -3.0
Blood Red Count 0.2 2.3 4.5 2.1 0.3
Blood White Count 0.2 1.4 1.9 1.4 1.0
Heel T-Score 3.3 26.6 37.0 6.1 -4.0
BMI 0.4 2.5 3.7 -1.1 -1.9
Height 1.6 31.4 58.4 -7.6 2.1
Waist Hip Ratio (WHR) 0.1 0.4 0.8 0.9 -0.2
Systolic Blood Pressure 0.1 0.5 0.9 -1.0 0.4
Smoking Status 1.4 3.4 6.3 2.5 -0.8
Allergy or Eczema 0.1 0.3 0.5 -0.7 0.1
Cardiovascular Disease 0.4 1.4 2.8 -1.7 -0.1
Hypothyroidism (self reported) 0.3 0.7 1.0 1.0 -0.6
Respiratory disease 0.1 0.2 0.4 0.6 -0.2
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.1 0.0 0.3
Lung FEV1/FVC ratio 0.2 0.9 1.2 -0.8 1.1
Lung FVC 0.9 4.8 7.6 -1.4 2.8
Neuroticism 0.1 0.3 0.4 -0.6 0.4
Chronotype (morning person) 0.1 0.2 0.3 -0.6 -0.1
Hair Pigment 0.2 5.1 9.4 0.9 3.1
Tanning 0.0 0.3 0.5 0.7 -0.3
Hand grip strength (left) 0.9 2.3 3.3 -1.8 1.2
Number of treatments/medications taken 0.1 0.2 0.3 -0.6 0.3
Average weekly spirits intake 0.6 0.8 1.2 1.1 -0.6
Sensitivity / hurt feelings 0.1 0.2 0.4 -0.0 -0.7
Frequency of depressed mood in last 2 weeks 2.6 3.7 4.0 -1.8 2.0
Hearing difficulty/problems: Yes 0.7 1.1 1.9 -0.6 -1.4
Relative age of first facial hair 0.0 0.1 0.2 0.4 0.0
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 1.5 0.7 1.2
Ever used hormone-replacement therapy (HRT) 1.0 1.2 1.6 1.3 -0.9
Ever had hysterectomy (womb removed) 1.5 1.7 2.9 -1.7 -0.7
Systolic blood pressure, automated reading 0.0 0.1 0.1 -0.4 -0.1
Eye problems/disorders: Diabetes related eye disease 1.7 1.9 2.9 -1.7 1.0
Angina 1.6 2.1 3.9 -2.0 -0.5
Medication for hormone replacement therapy 0.3 0.4 0.7 0.2 0.8
Vitamin and mineral supplements 1.3 1.8 3.4 -0.4 -1.8
Supplements: Zinc 1.7 1.8 2.9 1.7 -0.8
Medication: Co-codamol 3.2 3.7 4.0 2.0 -1.8
Medication: Metformin 0.4 0.6 0.7 -0.8 -0.7
Diabetes (father) 0.5 0.6 1.1 0.2 -1.0
Diabetes (mother) 0.8 1.0 2.1 1.4 -0.1
Severe depression (siblings) 0.6 0.7 0.7 -0.8 0.9
Pack years adult smoking proportion 0.0 0.0 0.0 0.0 -0.2
Impedance of leg (right) 2.5 11.9 18.8 4.3 -2.3
Leg fat-free mass (left) 2.6 13.7 25.4 -5.0 1.4
Trunk fat percentage 0.6 2.4 4.7 0.2 -2.2
Hand grip strength (right) 0.3 0.8 1.5 -1.2 0.4
Townsend deprivation index at recruitment 0.0 0.0 0.0 0.1 -0.2
Current tobacco smoking 1.0 1.7 3.4 1.8 0.0
Average weekly fortified wine intake 0.5 0.6 0.7 0.8 -0.8
Maternal smoking around birth 1.6 2.3 3.1 1.2 -1.8
Fed-up feelings 0.1 0.2 0.3 0.2 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 3.3 4.5 5.2 -1.9 2.3
Relative age voice broke 0.8 1.2 2.1 -0.6 1.4
Taking other prescription medications 0.0 0.0 0.0 0.2 -0.0
Age when periods started (menarche) 5.8 14.0 27.8 5.3 -0.4
Bilateral oophorectomy (both ovaries removed) 6.9 8.0 15.0 -3.9 1.0
Heel bone mineral density (BMD) T-score, automated (left) 3.2 7.2 11.1 3.3 -1.8
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 0.8 0.0 0.9
Qualifications: CSEs or equivalent 3.7 4.9 5.8 2.0 -2.4
Serious illness, injury or assault to yourself 0.7 0.8 1.6 -0.2 1.2
High blood pressure 0.3 0.9 1.6 -1.3 -0.4
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.5 -0.7 -0.1
Multivitamins +/- minerals 0.5 0.7 1.3 0.2 1.1
Stomach or abdominal pain in last month 0.1 0.1 0.1 -0.2 -0.3
Supplements: Glucosamine 0.2 0.2 0.4 -0.6 0.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 0.8 -0.9 -0.4
Medication: Atenolol 0.0 0.0 0.0 -0.2 -0.1
Medication: Levothyroxine sodium 0.5 0.8 1.3 1.1 -0.6
Sitting height 0.7 5.1 9.5 -3.1 0.8
Chronic bronchitis/emphysema (father) 0.2 0.2 0.4 0.3 -0.6
High blood pressure (mother) 0.2 0.3 0.4 -0.2 0.7
Body mass index (BMI) 0.3 1.3 1.5 -1.2 -1.1
Impedance of leg (left) 2.8 13.4 20.6 4.5 -2.5
Leg predicted mass (left) 2.5 13.4 24.8 -5.0 1.4
Trunk fat mass 0.5 2.0 2.3 -1.2 -1.5
Waist circumference 0.3 1.2 1.4 -1.2 -1.0
Number of incorrect matches in round 4.3 7.1 7.7 -2.5 2.8
Past tobacco smoking 1.3 2.3 4.4 -2.1 0.5
Alcohol usually taken with meals 1.1 1.7 2.4 -1.5 1.0
Nervous feelings 0.7 1.3 2.5 1.6 -0.4
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 1.1 -0.6 1.0
Hearing difficulty/problems with background noise 0.2 0.3 0.3 -0.4 -0.6
Hair/balding pattern: Pattern 2 0.8 1.0 1.3 -1.1 -0.9
Had menopause 0.5 0.6 1.0 -0.4 -1.0
Had other major operations 0.6 0.8 0.8 0.9 -0.9
Forced vital capacity (FVC) 1.3 5.0 5.8 -2.4 2.1
Heel bone mineral density (BMD) T-score, automated (right) 4.4 10.2 13.5 3.7 -2.6
Ever unenthusiastic/disinterested for a whole week 2.5 3.0 4.4 -2.1 1.3
Qualifications: None of the above 0.1 0.2 0.4 -0.1 -0.6
Financial difficulties in last 2 years 0.4 0.5 1.1 -0.1 1.0
Mouth/teeth dental problems 0.1 0.2 0.3 0.2 0.6
Heart attack 0.2 0.3 0.5 -0.7 0.3
Allergy 0.3 0.6 1.0 1.0 -0.4
Pain all over the body in last month 0.2 0.3 0.4 -0.7 -0.3
Diabetes (self-reported) 0.6 0.9 1.3 -0.7 1.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 0.8 -0.9 -0.2
Medication: Ramipril 1.0 1.3 1.5 1.1 -1.2
Medication: Simvastatin 0.3 0.5 0.8 -0.3 -0.9
Fluid intelligence score 1.5 3.1 3.3 1.8 -1.7
Illnesses of siblings 0.2 0.3 0.4 0.7 0.3
Neuroticism score 0.1 0.3 0.3 -0.5 0.5
Weight 1.2 5.9 11.7 -3.4 -0.4
Impedance of arm (right) 0.3 1.3 2.3 1.5 0.4
Arm fat percentage (right) 0.1 0.4 0.6 -0.5 -0.8
Trunk fat-free mass 2.5 14.4 26.5 -5.2 1.5
Hip circumference 0.6 2.8 5.1 -2.3 -0.7
Time employed in main current job 0.2 0.3 0.5 -0.7 -0.2
Alcohol intake versus 10 years previously 0.0 0.0 0.0 -0.1 0.1
Father’s age at death 0.5 0.7 0.9 0.7 -0.9
Worrier / anxious feelings 0.1 0.2 0.5 -0.7 0.1
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.8 2.3 -1.5 1.1
Falls in the last year 0.1 0.2 0.3 0.2 -0.6
Hair/balding pattern: Pattern 3 0.6 1.0 1.2 0.9 1.1
Number of live births 7.4 10.4 19.4 -4.4 1.2
Forced expiratory volume in 1-second (FEV1) 1.6 5.3 5.4 -2.3 2.3
Pulse rate 0.1 0.1 0.2 -0.4 0.3
Happiness 0.6 0.8 0.8 -0.9 0.9
Noisy workplace 0.5 0.6 0.9 0.9 -0.6
Qualifications: A levels/AS levels or equivalent 0.1 0.3 0.5 -0.2 0.7
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.5 0.0 0.7
Mouth/teeth dental problems: Dentures 0.2 0.3 0.6 0.3 -0.8
Asthma 0.1 0.2 0.4 0.1 0.6
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 1.4 0.3 -1.2
Medication: Cholesterol lowering 0.0 0.0 0.1 0.0 -0.2
Depression (self-reported) 0.1 0.1 0.2 -0.2 0.5
Medication: Lansoprazole 1.1 1.2 1.4 1.2 -1.0
Prospective memory result 0.4 0.5 0.9 -1.0 0.4
Lung cancer (father) 0.5 0.6 1.0 -0.4 1.0
Illnesses of mother 0.1 0.1 0.1 0.1 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 6.0 7.2 -2.7 2.2
Pulse wave Arterial Stiffness index 0.0 0.1 0.1 0.0 -0.3
Impedance of arm (left) 0.2 0.8 1.6 1.3 0.1
Arm fat mass (right) 0.6 2.6 5.1 -2.3 -0.4
Trunk predicted mass 2.6 14.6 26.8 -5.2 1.5
Standing height 1.4 14.0 26.1 -5.1 1.4
Length of working week for main job 1.2 1.3 2.0 0.8 -1.4
Exposure to tobacco smoke at home 0.2 0.2 0.2 0.5 0.4
Breastfed as a baby 0.1 0.1 0.2 -0.1 -0.4
Tense / ‘highly strung’ 0.4 0.6 1.0 -0.5 1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.1 0.1 -0.4 0.1
Hair/balding pattern: Pattern 4 0.1 0.2 0.4 0.6 0.1
Birth weight of first child 4.2 7.5 8.3 -2.9 2.6
Peak expiratory flow (PEF) 1.5 3.5 5.1 -2.2 1.4
Pulse wave reflection index 0.5 0.6 1.2 1.1 -0.1
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.4 -0.7 -0.4
Loud music exposure frequency 0.9 1.0 1.1 0.9 1.0
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 0.8 -0.9 0.5
Mouth/teeth dental problems: Bleeding gums 0.3 0.3 0.5 -0.7 0.5
Blood clot in the leg (DVT) 1.4 1.8 3.5 -1.9 -0.4
Medication: Paracetamol 0.5 0.8 1.4 1.2 -0.3
Headache pain in last month 0.2 0.4 0.7 0.0 0.9
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.1 1.0 0.0
Glaucoma (self-reported) 1.0 1.1 1.5 1.2 -0.9
Gout (self-reported) 0.7 1.0 1.7 0.5 -1.3
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 0.6 0.8 0.1
Medication: Amlodipine 0.3 0.4 0.6 -0.8 -0.4
Medication: Ventolin 100micrograms inhaler 0.3 0.4 0.4 -0.6 0.6
Birth weight 2.7 5.8 8.2 -2.9 1.8
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.1 0.4 0.3
High blood pressure (siblings) 0.2 0.4 0.6 -0.8 -0.3
Forced vital capacity (FVC), Best measure 1.3 4.6 6.2 -2.5 1.7
Body fat percentage 0.6 2.3 4.3 0.6 -2.1
Leg fat percentage (right) 0.8 2.8 4.8 0.9 -2.2
Arm fat-free mass (right) 1.5 7.5 15.1 -3.9 0.1
Exposure to tobacco smoke outside home 0.4 0.6 0.8 -0.9 0.7
Comparative body size at age 10 0.8 2.2 3.0 -1.7 1.2
Number of full brothers 2.1 2.7 3.1 1.8 -1.5
Worry too long after embarrassment 0.6 1.1 1.7 1.3 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 0.9 -0.4 0.9
Wheeze or whistling in the chest in last year 0.1 0.1 0.2 0.4 -0.2
Number of children fathered 0.1 0.1 0.3 -0.5 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 0.7 -0.1 0.8
Age at first live birth 2.0 3.5 6.5 2.5 -0.8
Pulse wave peak to peak time 0.3 0.3 0.3 -0.6 0.5
Health satisfaction 0.4 0.5 1.0 -1.0 -0.3
Shortness of breath walking on level ground 1.4 1.6 2.8 0.7 -1.7
Qualifications: College or University degree 0.1 0.4 0.8 0.9 -0.0
Eye problems/disorders: None of the above 0.9 1.0 1.4 0.8 -1.2
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.2 -0.4 0.1
Emphysema/chronic bronchitis 1.7 1.9 2.4 1.6 -1.2
Medication for pain relief, constipation, heartburn 0.0 0.1 0.1 -0.3 0.1
Neck or shoulder pain in last month 0.4 0.6 0.7 0.7 -0.8
Medication: Blood pressure 0.1 0.2 0.2 -0.3 -0.5
Angina (self-reported) 1.7 2.3 4.2 -2.1 -0.5
Migraine (self-reported) 1.7 2.2 3.3 1.8 -1.0
Medication: Ibuprofen 0.3 0.3 0.5 -0.4 -0.7
Medication: Allopurinol 1.4 1.8 2.7 1.0 -1.6
Medication: Omeprazole 0.5 0.6 0.7 -0.8 0.8
Medication: Seretide 50 evohaler 0.3 0.3 0.5 0.4 0.7
Mean time to correctly identify matches 1.7 3.2 3.4 -1.7 1.8
Heart disease (mother) 1.3 1.6 1.8 -1.3 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.2 -0.0 0.5
Whole body fat mass 0.4 1.7 1.8 -1.3 -1.3
Leg fat mass (right) 0.4 1.5 1.6 -1.2 -1.3
Arm predicted mass (right) 1.6 8.2 16.2 -4.0 0.3
Pulse rate, automated reading 0.5 1.6 2.4 -0.9 1.5
Alcohol intake frequency. 1.6 3.8 6.3 -2.5 1.1
Comparative height size at age 10 0.6 3.1 6.1 -2.5 0.4
Number of full sisters 0.0 0.1 0.1 -0.3 -0.2
Suffer from ‘nerves’ 0.2 0.4 0.8 0.1 0.9
Overall health rating 0.1 0.1 0.3 -0.5 -0.1
Chest pain or discomfort 0.7 1.0 1.7 -1.3 0.6
Had major operations 1.8 2.1 3.0 -1.7 1.1
Age at last live birth 0.4 0.5 1.1 1.0 0.2
Family relationship satisfaction 0.0 0.0 0.0 0.1 -0.1
Leg pain on walking 0.6 0.7 1.1 -0.5 -1.1
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 0.5 -0.3 0.7
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.1 0.3 -0.2
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 0.8 -0.7 -0.9
Medication: Aspirin 0.8 1.1 2.0 -1.4 0.3
Supplements: Vitamin C 1.0 1.1 2.1 0.4 1.5
Knee pain experienced in last month 1.0 1.5 2.8 -0.5 -1.7
Hypertension (Self-reported) 0.4 1.1 2.1 -1.4 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 0.2 0.5 -0.4
Illnesses of father: Heart disease 1.1 1.5 3.0 0.0 -1.7
Illnesses of siblings: Diabetes 0.0 0.0 0.1 -0.0 -0.3
Smoking status: Previous 1.0 1.6 2.6 1.6 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.4 2.5 -1.6 0.5
Whole body fat-free mass 2.5 14.5 27.1 -5.2 1.4
Leg fat-free mass (right) 2.7 14.4 26.4 -5.1 1.6
Arm fat percentage (left) 0.1 0.5 0.6 -0.7 -0.8
Average weekly red wine intake 0.2 0.3 0.4 0.6 -0.4
Handedness (chirality/laterality): Left-handed 0.5 0.6 0.7 0.7 -0.8
Mood swings 0.1 0.2 0.4 -0.2 0.6
Loneliness, isolation 1.8 2.4 2.8 -1.4 1.7
Long-standing illness, disability or infirmity 0.4 0.6 1.1 0.1 1.1
Ever had bowel cancer screening 1.6 1.9 3.2 1.8 -0.8
Diabetes diagnosed by doctor 0.1 0.1 0.2 -0.4 0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 1.6 -0.1 -1.2
Friendships satisfaction 0.5 0.6 0.7 0.7 -0.9
Qualifications: nursing, teaching 0.1 0.2 0.3 -0.1 0.6
Commuting to job workplace: Walk 0.0 0.0 0.0 -0.1 0.2
Eye problems/disorders: Cataract 1.1 1.3 1.7 -0.9 1.3
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 0.5 -0.7 -0.7
Medication for cholesterol 1.5 2.3 2.9 1.3 -1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.0 0.0 0.1 -0.2 0.2
Back pain experienced in last month 0.1 0.2 0.3 0.0 0.6
Mineral and other dietary supplements 0.8 1.0 1.6 1.3 -0.6
Breast cancer (self-reported) 1.9 2.2 3.0 1.2 1.7
Asthma (self-reported) 0.1 0.2 0.4 -0.1 0.6
Osteoporosis (self-reported) 2.3 2.8 2.8 -1.7 1.7
Osteoarthritis (self-reported) 0.2 0.2 0.4 -0.2 0.6
Medication: Aspirin 0.8 1.0 1.8 -1.3 0.5
Medication: Gliclazide 0.1 0.1 0.2 0.4 0.3
Illnesses of father: None of the above (group 1) 2.0 2.4 4.7 -0.4 2.2
Smoking status: Current 1.6 2.6 4.9 2.2 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.1 -0.4 1.0
Whole body water mass 2.5 14.0 26.0 -5.1 1.4
Leg predicted mass (right) 2.7 14.3 26.2 -5.1 1.5
Arm fat mass (left) 0.5 2.2 4.2 -2.0 -0.5
Number of self-reported non-cancer illnesses 0.1 0.2 0.3 -0.5 -0.4
Average weekly champagne plus white wine intake 0.7 0.9 1.6 -0.5 1.3
Miserableness 0.1 0.1 0.2 -0.5 0.3
Guilty feelings 0.2 0.3 0.4 -0.4 0.7
Wears glasses or contact lenses 0.2 0.3 0.5 -0.7 -0.1
Ever taken oral contraceptive pill 0.6 0.6 1.0 -0.5 -1.0
Hearing aid user 1.6 1.8 3.0 1.7 -0.8
Mother’s age at death 0.0 0.0 0.1 0.2 -0.1
Financial situation satisfaction 0.0 0.0 0.0 -0.1 -0.1
Tinnitus: Yes, now most or all of the time 0.6 0.6 0.7 0.8 -0.8
Commuting to job workplace: Public transport 0.1 0.2 0.2 0.5 0.4
Eye problems/disorders: Glaucoma 0.8 0.9 1.4 1.2 -0.7
Medication: Blood pressure 1.1 2.1 3.0 -1.7 1.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.5 -0.5 -1.2
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.0 -1.0 0.4
High cholesterol (Self-reported) 0.2 0.4 0.6 0.8 -0.5
Medication: Bendroflumethiazide 0.1 0.1 0.1 -0.3 -0.3
Medication: Paracetamol 0.2 0.3 0.5 0.7 -0.1
Medication: Lisinopril 1.1 1.4 1.4 -1.2 1.2
Medication: Atorvastatin 0.8 1.0 2.0 -0.1 1.4
Illnesses of father: High blood pressure 0.6 0.8 1.2 -1.1 -0.6
Alcohol drinker status: Never 0.1 0.1 0.2 -0.3 -0.4
Ever smoked 0.9 1.7 3.3 1.8 -0.1
Basal metabolic rate 2.3 12.6 24.0 -4.9 1.1
Leg fat percentage (left) 0.8 3.0 5.2 0.9 -2.3
Arm fat-free mass (left) 1.7 8.5 16.9 -4.1 0.3
Number of operations (self-reported) 0.9 1.3 2.0 -0.8 -1.4
Average weekly beer plus cider intake 0.5 0.7 1.1 1.0 -0.6
Irritability 0.0 0.0 0.0 -0.1 0.2
Risk taking 2.2 3.3 6.5 2.5 0.3
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.5 -0.7 -0.2
Fractured/broken bones in last 5 years 0.0 0.0 0.0 -0.2 0.1
Age started oral contraceptive pill 0.8 1.0 1.1 0.9 -1.1
Diastolic blood pressure, automated reading 0.0 0.1 0.1 -0.4 0.1
Ever depressed for a whole week 3.3 4.1 6.4 -2.5 1.3
Unable to work because of sickness or disability 0.4 0.5 1.0 1.0 -0.0
Commuting to job workplace: Cycle 0.3 0.4 0.7 0.2 0.8
Myopia 0.9 1.3 1.5 1.2 -1.1
Vascular/heart problems diagnosed by doctor 0.7 1.9 3.7 1.9 -0.2
Cholesterol lowering medication 0.0 0.1 0.1 -0.3 0.1
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 0.2 -0.1 0.4
Pain experienced in last month 0.5 0.9 1.5 1.2 -0.5
Supplements: Calcium 1.0 1.1 2.1 0.3 1.5
Basal cell carcinoma (self-reported) 1.7 2.0 3.5 1.9 -0.7
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.6 -0.8 0.3
Deep venous thrombosis (DVT) (self-reported) 1.7 2.2 4.4 -2.1 -0.2
Heart disease (siblings) 0.4 0.5 0.9 -1.0 0.3
Alcohol drinker status: Previous 0.4 0.5 0.5 -0.6 0.7
Pack years of smoking 0.1 0.1 0.2 -0.1 -0.4
Impedance of whole body 1.2 6.1 10.4 3.2 -1.4
Leg fat mass (left) 0.5 1.8 2.5 -1.1 -1.6
Arm predicted mass (left) 1.5 7.8 15.4 -3.9 0.3