[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr4:85,698,680-88,430,396

Best TWAS P=1.81e-09 · Best GWAS P=2.06e-09 conditioned to 0.621

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPN13 0.13 0.18 bslmm 418 0.18 6.8e-22 5.1 -5.5 3.7e-08 -0.53 0.44 0.56 FALSE
2 GTEx Artery Aorta MAPK10 0.15 0.17 enet 16 0.17 1.4e-09 5.8 -5.7 1.1e-08 -0.96 0.01 0.99 FALSE
3 GTEx Artery Aorta ARHGAP24 0.24 0.13 enet 8 0.14 2.2e-08 -4.2 -5.3 1.1e-07 -0.10 0.05 0.94 FALSE
4 GTEx Artery Aorta RP13-514E23.2 0.26 0.09 lasso 6 0.10 2.2e-06 -5.8 -5.6 2.6e-08 -0.08 0.02 0.98 FALSE
5 GTEx Artery Tibial ARHGAP24 0.26 0.19 enet 14 0.21 2.7e-16 -5.8 -5.5 4.8e-08 -0.05 0.01 0.99 FALSE
6 GTEx Artery Tibial RP13-514E23.2 0.22 0.16 enet 10 0.18 1.2e-13 -5.8 -5.8 7.9e-09 -0.07 0.01 0.99 TRUE
7 GTEx Colon Sigmoid MAPK10 0.25 0.11 lasso 8 0.07 1.6e-03 5.9 -6.0 1.8e-09 -0.89 0.02 0.96 TRUE
8 GTEx Thyroid PTPN13 0.41 0.31 lasso 6 0.30 3.2e-23 6.0 5.9 3.8e-09 0.99 0.01 0.99 FALSE
9 ROSMAP Brain Pre-frontal Cortex PTPN13 0.09 0.03 blup 409 0.07 4.7e-09 5.1 -5.7 1.1e-08 -0.53 0.41 0.59 FALSE