Best TWAS P=1.29e-10 · Best GWAS P=2.89e-14 conditioned to 0.0122
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | NEO1 | 0.07 | 0.09 | lasso | 2 | 0.09 | 3.9e-07 | -5.2 | -5.2 | 2.0e-07 | 0.45 | 0.93 | 0.02 | FALSE |
| 2 | GTEx | Pituitary | BBS4 | 0.27 | 0.02 | enet | 21 | 0.05 | 2.1e-02 | -4.9 | -6.3 | 3.2e-10 | 0.69 | 0.05 | 0.50 | FALSE |
| 3 | GTEx | Spleen | NEO1 | 0.39 | 0.00 | lasso | 9 | 0.01 | 2.0e-01 | 5.2 | -5.5 | 3.5e-08 | 0.25 | 0.05 | 0.11 | TRUE |
| 4 | GTEx | Testis | ADPGK-AS1 | 0.17 | 0.05 | lasso | 4 | 0.03 | 1.3e-02 | -4.6 | 6.4 | 1.3e-10 | -0.72 | 0.02 | 0.90 | TRUE |
| 5 | NTR | Blood | NEO1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 4.1e-06 | 5.5 | -5.4 | 6.5e-08 | 0.25 | 0.91 | 0.03 | FALSE |