Best TWAS P=3.24e-08 · Best GWAS P=1e-11 conditioned to 0.00391
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADARB1 | 0.12 | 0.03 | blup | 656 | 0.03 | 0.00036 | -4.2 | -5.5 | 4.0e-08 | 0.51 | 0.31 | 0.64 | TRUE |
| 2 | GTEx | Muscle Skeletal | PTTG1IP | 0.07 | 0.01 | enet | 6 | 0.00 | 0.09740 | -6.4 | 5.4 | 6.6e-08 | -0.71 | 0.01 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ADARB1 | 0.07 | 0.01 | blup | 139 | 0.04 | 0.00451 | 4.8 | -5.1 | 2.9e-07 | 0.83 | 0.01 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C21orf122 | 0.20 | 0.04 | lasso | 6 | 0.08 | 0.00026 | 5.7 | -5.5 | 3.2e-08 | 0.57 | 0.00 | 0.99 | TRUE |