Best TWAS P=3.52e-09 · Best GWAS P=1.59e-08 conditioned to 0.0948
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BCL2L13 | 0.19 | 0.09 | lasso | 13 | 0.12 | 5.9e-15 | 5.6 | -5.5 | 4.0e-08 | -0.87 | 0.00 | 0.99 | FALSE |
2 | GTEx | Artery Tibial | BID | 0.15 | 0.07 | enet | 21 | 0.07 | 6.3e-06 | 4.9 | -5.2 | 1.7e-07 | -0.83 | 0.01 | 0.99 | FALSE |
3 | GTEx | Brain Cortex | BID | 0.25 | 0.19 | lasso | 7 | 0.12 | 3.4e-04 | 4.9 | -5.1 | 2.7e-07 | -0.90 | 0.03 | 0.92 | FALSE |
4 | YFS | Blood | BCL2L13 | 0.08 | 0.07 | bslmm | 544 | 0.10 | 1.6e-30 | 4.9 | 5.9 | 3.5e-09 | 0.78 | 0.02 | 0.98 | TRUE |