[Hub]/) : Traits : Leg fat percentage (left) :

chr22:37,528,576-39,355,109

Best TWAS P=1.31e-09 · Best GWAS P=1.62e-08 conditioned to 0.922

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BAIAP2L2 0.11 0.03 lasso 5 0.04 1.8e-04 4.6 -5.9 3.2e-09 -0.75 0.03 0.86 TRUE
2 GTEx Artery Aorta C22orf23 0.10 0.01 enet 24 0.02 1.6e-02 2.8 5.4 8.7e-08 0.34 0.25 0.10 FALSE
3 GTEx Artery Aorta PLA2G6 0.10 0.02 enet 9 0.02 4.5e-02 3.2 5.4 5.2e-08 0.67 0.08 0.59 FALSE
4 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 4.9 -5.2 2.2e-07 -0.67 0.06 0.73 FALSE
5 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 5.2 -6.1 1.3e-09 -0.73 0.03 0.74 TRUE
6 GTEx Brain Cortex TMEM184B 0.29 0.12 lasso 7 0.09 1.6e-03 4.9 -5.4 7.7e-08 -0.90 0.01 0.88 FALSE
7 GTEx Cells Transformed fibroblasts ANKRD54 0.11 0.09 lasso 4 0.09 5.3e-07 -5.1 -5.2 1.8e-07 -0.20 0.14 0.83 FALSE
8 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 5.6 -5.5 3.6e-08 -0.99 0.01 0.99 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 5.6 5.8 6.6e-09 0.85 0.01 0.84 FALSE