TWAS hub - DHRS7B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1040	0.0420	3.0e-03	0.046	NA	0.045	NA	0.048	2.0e-03	NA	2.3e-03	NA	1.6e-03
2	GTEx	Colon Transverse	0.1020	0.0400	1.8e-03	0.086	NA	0.044	NA	0.073	6.9e-05	NA	3.5e-03	NA	2.3e-04
3	GTEx	Esophagus Muscularis	0.1190	0.0490	1.4e-03	0.095	NA	0.037	NA	0.086	2.2e-06	NA	2.5e-03	NA	6.8e-06
4	GTEx	Muscle Skeletal	0.0747	0.0339	3.7e-03	0.008	NA	0.047	NA	0.025	4.4e-02	NA	2.1e-05	NA	1.7e-03
5	GTEx	Pituitary	0.2330	0.0940	7.5e-03	0.021	NA	0.015	NA	0.043	9.7e-02	NA	1.3e-01	NA	3.1e-02
6	GTEx	Thyroid	0.1670	0.0450	7.7e-08	0.025	NA	0.108	NA	0.065	5.0e-03	NA	1.3e-08	NA	1.1e-05
7	ROSMAP	Brain Pre-frontal Cortex	0.0527	0.0214	1.1e-03	0.022	0.025	0.021	0.025	0.017	6.1e-04	2.7e-04	9.1e-04	0.00026	2.7e-03
8	YFS	Blood	0.0290	0.0113	8.5e-05	0.018	0.013	0.012	NA	0.013	1.3e-06	3.5e-05	5.2e-05	NA	2.1e-05
9	TCGA	Breast Invasive Carcinoma	0.0142	0.0080	2.1e-03	0.010	0.004	0.003	NA	0.000	2.9e-03	4.6e-02	7.2e-02	NA	2.6e-01
10	TCGA	Lung Adenocarcinoma	0.0242	0.0136	4.0e-03	0.015	0.020	0.019	NA	0.021	5.5e-03	1.7e-03	2.2e-03	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Overall health rating	7.4	15.9	25.3	-2.7	-4.7	-4.4	-2.6	-4.2	-5.0	-3.4	-3.8	-4.5	-3.8
Exposure to tobacco smoke outside home	7.0	9.3	23.2	-2.3	-4.2	-4.3	-1.7	-1.9	-4.8	-2.1	-1.9	-2.5	-2.8
Leg fat percentage (left)	6.9	24.8	45.1	-4.5	-6.0	-5.4	-2.0	-4.0	-6.7	-4.9	-3.9	-5.0	-5.8
Leg fat percentage (right)	6.0	21.6	41.3	-4.1	-5.7	-5.0	-2.0	-3.8	-6.4	-4.8	-3.4	-4.4	-5.3
Medication: Lansoprazole	4.9	5.6	17.3	-1.6	-2.6	-2.4	-1.7	-2.8	-4.2	-1.8	-2.0	-1.7	-1.8
Townsend deprivation index at recruitment	3.9	5.5	10.3	-2.0	-2.7	-2.7	-2.2	-3.2	-2.3	-1.2	-2.6	-2.0	-1.8
Body fat percentage	3.8	14.9	26.0	-3.0	-5.0	-4.3	-1.9	-3.2	-5.1	-4.0	-2.6	-3.7	-4.4
Leg fat mass (left)	3.8	14.8	26.5	-3.0	-4.6	-4.1	-1.6	-3.8	-5.2	-4.3	-3.0	-3.6	-4.1
Body mass index (BMI)	3.7	15.6	37.9	-3.0	-4.7	-4.1	-1.3	-4.0	-6.2	-4.0	-3.0	-3.3	-4.1
High blood pressure (siblings)	3.5	5.1	8.5	2.3	2.6	2.9	2.0	1.9	1.6	2.3	1.9	2.4	2.3
Leg fat mass (right)	3.4	13.0	23.8	-2.8	-4.4	-3.9	-1.5	-3.5	-4.9	-4.2	-2.6	-3.3	-3.9
Age when periods started (menarche)	3.2	7.6	19.9	2.7	2.3	2.2	1.4	3.4	4.5	2.3	2.8	2.4	2.5
Pain type(s) experienced in last month: Hip pain	3.2	4.0	8.4	-1.6	-2.0	-1.6	-1.8	-2.5	-2.9	-1.7	-1.7	-1.8	-2.1
Ever depressed for a whole week	3.1	3.8	7.6	2.7	0.9	1.7	0.0	2.3	1.0	2.8	2.1	2.0	2.2
Tinnitus: Yes, but not now, but have in the past	3.0	3.2	6.2	-2.0	-2.3	-2.3	-0.6	-0.9	-1.1	-1.6	-1.5	-2.0	-2.5
Prospective memory result	2.9	3.6	6.4	-1.6	-2.2	-2.1	-2.5	-1.2	-2.5	-2.1	-0.9	-1.3	-1.8
Age at First Birth	2.8	4.1	8.2	1.9	2.1	2.1	1.4	2.2	2.1	2.9	1.8	1.6	1.9
Waist circumference	2.6	9.4	18.2	-2.1	-3.7	-3.3	-1.1	-3.0	-4.3	-3.3	-2.6	-3.0	-3.2
Unable to work because of sickness or disability	2.6	3.4	6.7	-1.7	-1.6	-1.8	-1.1	-2.2	-2.4	-2.6	-1.4	-1.5	-1.6
Trunk fat percentage	2.5	10.1	19.5	-2.2	-4.4	-3.8	-1.8	-2.6	-4.0	-3.3	-2.0	-3.1	-3.5
Arm fat percentage (left)	2.5	9.8	19.6	-2.2	-4.2	-3.5	-1.5	-2.6	-4.4	-3.3	-2.1	-2.9	-3.4
Alcohol intake frequency.	2.4	5.5	10.7	-2.3	-2.2	-2.3	-2.3	-3.2	-3.3	-2.3	-2.2	-1.3	-1.4
Arm fat percentage (right)	2.3	9.0	17.9	-2.1	-4.2	-3.3	-1.4	-2.4	-4.2	-3.2	-1.8	-2.6	-3.4
Whole body fat mass	2.3	9.6	15.4	-2.3	-3.9	-3.3	-1.5	-3.2	-3.9	-3.5	-2.2	-2.9	-3.4
Chest pain or discomfort	2.3	3.3	6.0	-1.9	-1.6	-1.4	-2.5	-1.8	-1.3	-1.7	-1.7	-2.0	-2.1
Standing height	2.2	21.4	75.0	4.3	5.2	4.4	1.9	3.0	8.7	2.9	3.9	3.9	4.8
Medication: Omeprazole (e.g. Zanprol)	2.2	2.6	4.3	-1.3	-1.6	-1.5	-0.6	-1.3	-2.1	-2.0	-1.9	-1.8	-1.8
Medication: Omeprazole	2.1	2.6	3.7	-1.5	-1.8	-1.8	-1.0	-0.8	-1.9	-1.9	-1.4	-1.6	-1.9
Ever had bowel cancer screening	2.1	2.5	5.4	-1.4	-1.9	-1.4	-0.3	-0.7	-1.4	-1.5	-1.8	-2.3	-1.9
Osteoporosis (self-reported)	2.1	2.6	4.6	-1.2	-1.6	-1.5	-0.4	-1.6	-1.9	-1.7	-2.1	-2.0	-1.2
Angina	2.0	2.6	5.3	-1.0	-1.2	-0.9	-0.6	-1.9	-2.3	-2.0	-1.9	-1.9	-1.6
BMI	1.9	11.1	30.7	-2.1	-4.6	-3.8	-0.9	-3.2	-5.5	-3.1	-1.8	-2.3	-3.4
Sitting height	1.9	13.6	38.2	3.4	4.3	3.6	2.1	2.5	6.2	1.5	3.4	3.8	4.0
Arm fat mass (right)	1.9	7.9	14.1	-2.0	-3.6	-3.0	-1.1	-2.8	-3.8	-3.4	-1.9	-2.4	-3.0
Average weekly fortified wine intake	1.8	2.2	4.9	0.9	1.6	1.3	1.0	1.3	2.2	1.8	1.5	1.4	1.2
Pack years of smoking	1.8	2.6	6.2	-2.5	-1.1	-1.9	-0.1	-1.4	-1.5	-1.9	-1.0	-1.2	-2.2
Ovarian Cancer	1.7	2.2	4.6	-1.8	-1.7	-1.8	-0.5	-0.7	-1.7	-0.4	-2.1	-1.5	-1.5
Triglycerides	1.7	2.9	11.0	-1.3	-0.8	-1.1	-0.5	-3.3	-1.9	-1.5	-2.1	-1.4	-1.2
Medication: Levothyroxine sodium	1.7	3.0	8.5	-1.0	-1.5	-1.2	-1.4	-2.9	-2.0	-2.3	-1.4	-1.3	-1.2
Trunk fat mass	1.7	7.4	13.6	-1.9	-3.7	-3.2	-1.5	-2.7	-3.1	-3.1	-1.8	-2.5	-2.9
Hip circumference	1.7	7.1	12.3	-1.4	-3.4	-3.2	-1.5	-3.1	-3.0	-3.5	-2.0	-2.2	-2.3
Exposure to tobacco smoke at home	1.7	1.9	4.0	-1.7	-1.5	-2.0	-0.3	-0.9	-1.1	-1.4	-1.1	-1.0	-1.9
Illness, injury, bereavement, stress in last 2 years	1.7	2.0	5.3	-1.1	-2.3	-1.7	-1.9	-0.0	-1.8	-0.2	-0.3	-1.2	-1.6
Arm fat mass (left)	1.7	7.0	13.7	-1.7	-3.4	-2.9	-1.0	-2.9	-3.7	-3.1	-1.8	-2.2	-2.7
Alzheimer’s Disease (in mother)	1.6	1.9	3.5	-1.2	-1.2	-1.5	-1.0	-1.6	-1.9	-1.5	-0.9	-1.3	-1.4
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.9	-1.7	-1.0	-0.5	-0.6	-1.1	-0.6	-1.1	-2.0	-1.8	-1.9
Hypothyroidism (self reported)	1.6	3.8	10.6	-0.7	-1.5	-1.7	-0.5	-3.2	-2.6	-2.9	-1.5	-1.5	-1.1
Pack years adult smoking proportion	1.6	2.4	5.7	-2.4	-1.0	-1.9	0.1	-1.4	-1.3	-2.1	-1.0	-1.1	-2.0
Hypothyroidism/myxoedema (self-reported)	1.6	3.1	10.7	-0.2	-1.2	-0.8	-0.5	-3.3	-2.4	-2.9	-1.5	-1.0	-0.6
Neck or shoulder pain in last month	1.6	2.3	9.7	-0.9	-2.2	-1.9	-1.4	-0.1	-3.1	-0.0	0.1	-0.9	-1.4
Migraine (self-reported)	1.6	2.0	5.2	1.3	2.0	2.3	2.1	0.3	1.2	0.6	0.0	0.8	1.2
Reaction Time	1.5	2.9	5.9	1.8	2.4	2.2	1.7	1.3	1.7	0.5	1.3	1.3	1.9
Rheumatoid Arthritis	1.5	2.0	3.4	-1.5	-1.6	-1.5	0.0	-1.5	-1.3	-1.8	-1.2	-1.3	-1.6
Serious illness, injury or assault to yourself	1.5	1.8	4.9	-1.0	-0.3	-0.7	0.1	-2.2	-2.2	-1.6	-1.4	-1.3	-0.7
Financial difficulties in last 2 years	1.5	2.0	4.6	0.9	2.0	1.8	1.2	0.7	2.1	1.2	0.8	1.1	1.5
Age at first live birth	1.5	2.7	11.4	1.0	1.5	2.3	-0.3	1.8	3.4	1.8	0.7	0.2	0.3
Knee pain experienced in last month	1.5	2.3	5.3	-1.3	-2.3	-2.0	-2.2	-0.1	-1.8	-1.4	-0.6	-0.7	-1.3
Mother’s age at death	1.5	1.9	4.0	1.0	2.0	1.3	1.6	0.3	0.6	0.5	1.1	2.0	1.9
Height	1.4	26.3	89.3	4.0	5.5	4.6	0.9	4.9	9.4	3.7	5.0	4.5	4.8
Taking other prescription medications	1.4	2.2	7.5	-0.3	-1.8	-0.9	-1.0	-2.1	-2.7	-1.5	-1.6	-0.6	-0.5
Stomach or abdominal pain in last month	1.4	1.7	4.9	-1.1	-0.4	-0.7	1.1	-1.6	-1.3	-1.2	-2.2	-1.6	-1.1
High blood pressure (mother)	1.4	2.0	3.5	1.4	1.9	1.9	1.7	1.3	0.6	0.7	1.5	1.5	1.1
Impedance of arm (left)	1.4	6.4	18.7	2.6	1.8	1.9	-0.3	3.6	4.3	2.4	2.6	1.4	2.3
Number of full brothers	1.4	1.8	3.8	-1.9	-1.3	-1.6	-1.7	-0.7	-1.5	-1.7	-0.1	-0.2	-1.1
Angina (self-reported)	1.4	1.8	3.0	-0.8	-0.8	-0.6	-0.5	-1.6	-1.7	-1.7	-1.6	-1.7	-1.4
Smoking status: Previous	1.4	2.1	5.9	-0.9	-0.7	-1.2	-0.5	-2.4	-0.3	-1.8	-2.2	-1.5	-1.0
Number of self-reported non-cancer illnesses	1.4	2.4	7.1	-0.9	-0.6	-0.5	0.4	-2.7	-2.0	-1.3	-2.3	-1.6	-1.1
Impedance of arm (right)	1.3	6.0	17.1	2.5	1.5	1.8	-0.5	3.6	4.1	2.3	2.6	1.4	2.1
Blood clot in the leg (DVT)	1.3	1.7	3.1	-0.9	-1.1	-1.3	-0.1	-1.6	-1.7	-1.4	-1.8	-1.2	-0.9
Age at last live birth	1.3	1.8	7.2	0.6	1.4	1.9	0.9	1.7	2.7	1.3	0.2	-0.0	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	3.1	-1.4	-1.8	-1.4	-0.8	-1.3	-1.3	-0.4	-1.0	-1.2	-1.6
Myopia	1.3	2.0	6.5	1.1	1.6	1.8	0.3	0.5	2.5	1.8	0.2	0.9	1.3
Body Mass Index (BMI) (2010)	1.2	1.6	5.5	-0.7	-1.4	-1.6	-0.6	-1.6	-2.3	-1.5	-0.6	0.3	-0.2
Vitamin and mineral supplements	1.2	1.7	5.3	-0.9	-0.3	-0.4	0.8	-2.3	-0.8	-1.3	-2.2	-1.2	-1.0
Severe depression (siblings)	1.2	1.4	4.1	-1.5	-0.0	-0.0	0.5	-1.6	0.7	-1.0	-2.0	-1.3	-1.2
Mouth/teeth dental problems: Dentures	1.2	2.1	4.0	-1.3	-2.0	-1.8	-1.4	-1.0	-1.6	-1.8	-0.8	-1.2	-1.0
Medication: Blood pressure	1.2	2.2	6.0	-1.0	-1.2	-0.5	-0.9	-1.0	-1.9	-0.7	-1.9	-2.5	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	3.5	0.7	1.5	1.8	1.2	1.1	0.4	1.9	0.9	0.7	0.7
Number of full sisters	1.2	1.5	6.3	-0.1	-1.4	-0.6	-1.1	-1.2	-2.5	0.4	-1.2	-1.4	-0.3
Suffer from ‘nerves’	1.2	1.9	5.9	-1.1	-1.5	-1.6	-2.4	0.3	-1.0	-0.4	-0.7	-1.7	-1.5
Long-standing illness, disability or infirmity	1.2	1.8	5.0	-0.5	-0.9	-0.4	0.8	-1.7	-2.2	-1.8	-1.7	-1.1	-0.8
Basal cell carcinoma (self-reported)	1.2	1.4	4.8	0.7	2.2	1.9	0.9	-1.4	0.3	0.7	-0.3	0.7	0.9
HDL Cholesterol	1.1	1.9	4.2	1.0	0.9	1.2	-0.2	2.0	1.8	0.9	1.6	1.5	1.5
Blood White Count	1.1	8.1	14.4	3.3	3.8	3.2	3.4	1.1	1.3	2.3	2.4	3.2	3.1
Allergy or Eczema	1.1	3.0	6.4	1.3	2.3	2.1	0.6	1.6	1.4	2.5	1.7	1.4	1.6
Type 2 Diabetes (T2D) (2018)	1.1	2.1	3.6	1.7	0.8	1.7	0.6	1.5	-1.3	1.9	1.7	1.4	1.2
Medication: Ramipril	1.1	1.4	5.6	-0.1	-1.3	-1.1	-1.0	-1.7	-2.4	-1.1	-0.6	-0.5	0.0
Illnesses of siblings	1.1	1.5	3.2	-1.7	-0.9	-1.4	-0.4	-1.4	-0.3	-1.3	-0.9	-1.4	-1.8
Medication: Cholesterol lowering	1.1	1.7	4.4	-0.8	-1.2	-0.2	-2.1	-1.1	-2.1	-1.0	-1.2	-1.1	-1.1
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	2.9	0.8	1.7	1.5	0.4	1.5	1.7	1.5	1.1	1.1	1.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	5.2	0.8	1.2	0.2	1.2	1.0	2.3	0.6	1.8	1.9	1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	4.9	2.2	1.4	1.0	0.9	-0.0	2.2	0.5	1.1	1.6	2.2
Loneliness, isolation	1.1	1.6	3.5	1.7	0.9	0.7	0.3	0.7	0.1	1.2	1.6	1.7	1.9
Breast cancer (self-reported)	1.1	1.3	6.3	-0.6	-1.4	-1.1	-1.2	-0.9	-2.5	-0.7	-0.4	0.3	0.1
Medication: Gliclazide	1.1	1.3	2.0	1.2	1.1	0.9	1.3	1.0	-0.1	1.4	1.0	1.3	1.4
Cholesterol lowering medication	1.1	1.7	7.9	0.1	-1.0	-0.4	1.1	-1.6	-2.8	-0.9	-1.1	-1.2	-0.7
Schizophrenia vs Biploar Disorder	1.0	1.3	2.4	-1.0	-1.4	-0.9	0.0	-1.1	-1.6	-0.9	-1.5	-1.1	-1.1
Alzheimer’s Disease (in father)	1.0	1.1	2.7	1.6	0.5	1.1	0.9	1.0	0.6	1.0	1.1	0.7	1.2
Prostate Cancer	1.0	1.4	4.0	-0.5	-0.6	-1.2	1.7	-2.0	-1.6	-1.1	-1.0	-0.8	-0.4
Ulcerative Colitis	1.0	1.4	3.0	-1.7	-0.4	-1.4	-0.7	-1.5	-0.5	-1.2	-1.5	-1.0	-1.1
Smoking Status	1.0	2.3	7.4	-1.4	-0.4	-1.3	0.7	-2.7	-0.9	-1.9	-2.0	-1.5	-1.0
Lung FVC	1.0	4.9	12.0	-1.9	-1.6	-1.5	0.1	-3.5	-2.5	-1.6	-3.2	-2.2	-2.1
Hand grip strength (left)	1.0	2.6	7.7	1.1	1.9	1.5	1.7	1.9	2.8	1.0	1.0	1.2	1.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.7	0.7	1.0	1.1	1.2	1.2	0.7	1.7	0.6	1.1	1.0
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	2.4	1.5	0.5	0.9	0.2	0.7	1.3	0.6	1.2	1.4	1.6
Pain all over the body in last month	1.0	1.1	4.0	-2.0	-0.4	-0.7	-0.2	-1.1	1.0	-1.3	-0.7	-0.6	-1.1
Eye problems/disorders: Cataract	1.0	1.2	2.6	-1.2	-0.2	-1.1	-0.4	-1.5	-1.6	0.1	-1.5	-0.9	-0.7
Hearing aid user	1.0	1.1	2.6	1.0	1.2	0.7	0.9	0.3	-0.1	1.4	1.2	1.6	1.1
Financial situation satisfaction	1.0	1.3	2.9	1.7	1.1	0.9	1.3	1.2	-0.0	1.1	1.4	0.7	1.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.9	-0.9	-0.9	-1.1	-0.0	-1.4	-1.7	-1.0	-1.6	-1.0	-0.8
Sensitivity / hurt feelings	0.9	1.6	3.1	-0.6	-1.7	-1.8	-1.7	-1.1	-1.2	-1.6	-0.9	-1.0	-0.3
Supplements: Zinc	0.9	0.9	3.0	0.3	-0.1	0.3	-1.7	0.8	0.9	1.7	0.8	0.9	0.6
Hayfever, allergic rhinitis or eczema	0.9	2.0	4.2	0.8	2.0	1.8	1.1	1.3	1.1	2.0	0.9	1.1	1.3
Multivitamins +/- minerals	0.9	1.1	3.1	0.1	-0.7	-0.6	-1.8	1.6	0.1	1.3	1.6	0.7	0.4
Alcohol intake versus 10 years previously	0.9	1.3	4.4	-0.3	-1.1	-1.3	-0.2	-1.4	-2.1	-1.9	-0.3	-0.3	0.1
Father’s age at death	0.9	1.2	3.4	0.7	0.9	0.5	-0.1	0.7	1.8	1.8	1.0	1.3	0.9
Number of live births	0.9	1.3	2.7	-1.4	0.5	-0.3	1.1	-1.3	-1.6	-0.9	-1.5	-0.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.9	1.9	6.0	0.9	2.1	1.9	0.8	0.5	2.4	1.2	0.5	0.8	1.1
Gout (self-reported)	0.9	1.3	4.5	0.5	1.5	0.8	2.1	-0.8	1.1	-1.2	-1.3	-0.2	0.1
Comparative height size at age 10	0.9	5.2	11.6	2.2	2.8	2.7	1.2	1.3	3.4	1.6	2.2	2.0	2.5
Leg pain on walking	0.9	1.2	3.4	-0.4	-0.7	-0.4	-0.7	-1.8	-1.2	-0.9	-1.1	-1.4	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.3	-1.1	-1.5	-0.9	-1.1	-0.6	-0.3	-1.1	-0.8	-1.0	-1.1
Illnesses of father: Heart disease	0.9	1.3	2.0	1.4	1.4	0.9	1.1	1.2	0.6	1.4	0.8	0.9	1.2
Osteoarthritis (self-reported)	0.9	1.1	2.8	-1.0	-1.2	-0.4	-0.7	-0.7	-1.5	-0.3	-1.3	-1.1	-1.7
Bipolar Disorder or Schizophrenia	0.8	1.9	5.5	-1.3	0.6	-0.5	1.5	-2.4	-1.4	-1.8	-1.4	-0.7	-0.8
Ulcerative Colitis (UC)	0.8	1.5	3.5	-1.0	-0.9	-1.1	-0.9	-1.9	-1.1	-1.5	-1.4	-1.2	-1.0
Blood Red Count	0.8	7.5	14.0	3.2	2.1	2.3	-0.4	3.1	2.6	1.9	3.7	3.2	3.2
Hearing difficulty/problems: Yes	0.8	1.2	2.7	0.6	1.6	1.0	1.5	-0.3	1.7	0.8	0.7	1.1	0.5
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.3	-0.9	-1.0	-1.3	0.5	-0.9	-0.6	-1.5	-0.7	-1.1	-1.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	9.0	1.2	1.3	1.5	0.3	1.5	3.0	1.6	1.5	1.8	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	6.6	1.6	1.4	1.4	1.1	1.2	2.6	1.1	1.4	1.8	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	2.1	-0.8	-0.9	-0.9	0.3	-0.9	-1.5	-1.5	-1.1	-0.8	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.7	-0.3	1.0	0.9	1.9	0.9	1.7	0.5	-0.0	-0.1	-0.6
Medication: Allopurinol	0.8	1.1	2.2	0.9	1.5	0.9	1.3	-1.1	0.3	-1.5	-1.4	-0.2	0.7
Heart disease (siblings)	0.8	1.0	3.4	-0.4	-0.9	-0.6	-1.8	-0.7	-1.8	-0.9	-0.8	-0.1	0.3
Impedance of whole body	0.8	4.1	12.3	1.7	1.1	1.2	-0.6	3.5	3.5	2.0	2.0	0.7	1.4
Depression (Nagel 2018)	0.7	1.0	4.3	0.2	1.5	1.0	2.1	-0.7	0.8	-0.9	0.3	0.4	0.5
Schizophrenia (2018)	0.7	1.4	5.5	-0.6	1.2	0.1	1.4	-2.3	-1.2	-1.4	-1.1	0.0	-0.0
Irritable Bowel Disease (IBD)	0.7	1.7	5.3	-0.4	-0.8	-1.1	-0.7	-2.3	-1.1	-1.7	-1.7	-1.2	-0.7
Schizophrenia (2014)	0.7	1.6	5.5	-0.1	0.8	-0.0	1.3	-2.3	-1.7	-1.7	-1.4	-0.2	0.2
Qualifications: CSEs or equivalent	0.7	1.0	2.0	0.9	1.4	1.3	1.3	0.9	0.8	0.9	1.0	0.5	0.6
Medication: Atenolol	0.7	0.8	1.5	-0.1	-1.0	-0.7	-0.5	-1.2	-0.9	-1.1	-1.0	-1.2	-0.7
Mouth/teeth dental problems	0.7	1.0	2.9	1.7	0.9	0.9	1.4	0.6	0.4	1.0	0.3	0.8	1.3
Diabetes (self-reported)	0.7	1.1	5.6	0.6	-0.0	0.3	-1.1	0.3	-2.4	1.0	1.0	1.0	0.7
Medication: Simvastatin	0.7	1.1	6.3	0.2	-0.9	-0.1	-0.1	-1.1	-2.5	-0.5	-0.9	-1.0	-0.6
Weight	0.7	3.3	6.8	-1.0	-2.1	-1.9	-0.3	-2.5	-2.0	-2.6	-1.2	-1.5	-1.8
Number of children fathered	0.7	0.8	5.2	-0.4	0.9	1.0	2.3	-0.2	0.6	-0.6	-0.6	-0.3	-0.3
Qualifications: nursing, teaching	0.7	1.1	3.1	1.3	1.0	1.4	0.7	0.3	1.8	1.1	0.4	0.7	1.0
Ever taken oral contraceptive pill	0.7	0.8	2.1	-0.5	0.0	0.5	0.6	-0.9	0.6	-1.2	-1.5	-1.2	-0.8
Commuting to job workplace: Public transport	0.7	0.8	2.9	0.4	0.3	-0.2	-0.3	1.2	1.7	1.4	0.7	0.9	0.4
Eye problems/disorders: Glaucoma	0.7	0.8	1.8	1.1	0.8	0.8	-0.0	1.3	0.4	0.8	1.0	0.9	1.1
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.2	-0.6	-0.5	-0.4	-1.5	1.3	1.2	1.2	0.9	0.2	-0.7
Medication: Paracetamol	0.7	1.0	2.5	-1.4	-1.3	-1.0	-1.6	-0.3	-0.9	-0.9	-0.2	-0.4	-1.2
Alcohol drinker status: Never	0.7	0.9	4.0	-0.4	-1.0	-0.6	-2.0	-0.7	-1.6	-0.3	-0.2	-0.1	0.0
Irritability	0.7	1.1	3.4	-1.1	-0.4	-0.9	-0.6	-1.8	-1.1	-1.4	-1.2	-0.3	-0.4
Commuting to job workplace: Cycle	0.7	0.8	2.0	0.6	1.4	1.0	0.9	-0.7	0.9	0.7	0.4	1.0	1.0
Pain experienced in last month	0.7	1.2	2.4	1.3	1.6	1.2	1.5	-0.1	0.9	0.7	0.6	0.8	1.1
Supplements: Calcium	0.7	0.8	2.8	-0.8	-1.2	-1.1	-1.7	-0.3	0.1	-0.7	-0.9	-0.5	-0.3
Bipolar Disorder (2018)	0.6	0.9	1.9	-1.4	-0.5	-1.0	0.6	-0.9	-0.8	-0.9	-0.9	-1.2	-1.2
Worry (Nagel 2018)	0.6	1.2	3.7	-1.4	-0.1	-0.3	-0.1	-0.8	-1.9	-0.8	-1.2	-1.3	-1.3
Lupus	0.6	0.9	4.3	0.7	-0.3	0.3	-0.8	1.2	0.7	0.5	2.1	0.9	0.9
Primary Biliary Cirrhosis	0.6	0.9	2.2	-0.6	-1.2	-1.3	0.0	-0.8	-1.5	-1.1	0.0	-0.3	-1.0
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.7	0.9	1.3	1.1	0.9	-0.6	-0.2	-0.0	0.4	1.2	0.9
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.9	0.8	0.4	0.1	0.5	-0.1	-1.7	1.1	0.5	0.7	0.9
Medication: Co-codamol	0.6	0.7	2.4	-0.9	-0.1	-0.6	1.5	-1.1	-0.7	-0.5	-0.8	-0.3	-0.6
Maternal smoking around birth	0.6	0.8	2.0	-1.3	-1.1	-1.4	-0.7	-0.4	-0.5	-1.4	-0.6	-0.3	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	1.9	-1.1	-0.2	-0.5	-1.3	-1.0	0.1	-1.4	-0.1	-0.8	-0.9
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.2	0.3	-0.9	-0.5	-1.5	1.3	-0.1	0.3	0.9	0.7	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	3.2	1.2	1.4	1.7	0.9	-0.4	-0.0	1.0	0.4	1.5	1.8
Chronic bronchitis/emphysema (father)	0.6	0.7	2.0	-1.0	-0.5	-0.9	-1.0	-0.3	-0.9	-1.4	-0.5	-0.6	-0.7
Nervous feelings	0.6	1.1	2.4	-1.1	-1.2	-1.2	-1.2	0.5	-0.7	-0.1	-0.4	-1.5	-1.4
Hair/balding pattern: Pattern 2	0.6	0.8	3.2	0.4	0.9	1.8	0.2	1.1	1.3	0.3	0.5	0.6	0.3
Had menopause	0.6	0.8	1.8	-1.1	-0.6	-1.0	-0.3	-0.9	-0.8	-1.4	-0.2	-0.8	-1.0
Forced vital capacity (FVC)	0.6	2.2	8.1	1.2	1.4	1.6	0.9	0.6	2.9	1.1	1.0	1.4	1.4
Hair/balding pattern: Pattern 3	0.6	0.9	2.5	0.1	1.4	1.0	1.0	-0.3	-0.3	0.2	0.7	1.6	1.2
Breastfed as a baby	0.6	0.8	1.8	0.9	1.3	1.4	0.7	0.6	0.7	0.5	1.0	0.7	0.6
Tense / ‘highly strung’	0.6	0.9	1.5	1.2	1.1	1.2	0.9	0.5	0.6	1.0	0.5	0.9	1.2
Peak expiratory flow (PEF)	0.6	1.5	3.7	0.8	0.7	0.7	-0.8	0.8	1.8	1.3	1.5	1.9	1.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.0	-1.4	0.5	0.3	-0.4	0.2	1.4	0.2	-0.4	-0.9	-1.4
Headache pain in last month	0.6	1.0	3.7	-1.5	-1.0	-1.4	-1.9	0.3	-0.1	-0.3	-0.1	-0.1	-0.7
Forced vital capacity (FVC), Best measure	0.6	2.3	6.2	1.7	1.5	1.6	1.6	0.5	2.5	0.9	0.8	1.4	1.7
Mean time to correctly identify matches	0.6	1.1	3.2	0.7	1.8	1.4	0.9	0.1	1.5	-0.2	0.3	0.9	1.3
Heart disease (mother)	0.6	0.7	1.9	-1.4	-1.0	-0.8	-0.9	0.2	-0.9	-0.6	-0.3	-0.5	-1.0
Medication: Aspirin	0.6	0.8	1.4	0.8	1.0	0.9	0.0	0.5	-1.0	1.1	0.7	1.2	0.8
Average weekly red wine intake	0.6	0.9	3.0	0.4	1.4	1.7	0.3	1.0	0.6	1.2	0.6	0.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.8	-1.0	0.4	0.1	0.5	-1.2	-1.7	-1.0	-0.7	0.0	-0.3
Medication: Aspirin	0.6	0.8	1.9	0.6	1.0	1.3	0.0	0.7	-0.9	1.4	0.5	0.9	0.6
Wears glasses or contact lenses	0.6	0.7	3.2	-0.5	-0.7	-0.3	-0.9	0.1	1.8	-0.1	-0.5	-1.1	-0.9
High cholesterol (Self-reported)	0.6	1.1	4.2	-0.5	-1.2	-0.5	-0.8	-1.3	-2.0	-1.1	-0.8	-0.7	-0.6
Average weekly beer plus cider intake	0.6	0.8	1.5	-0.3	-1.2	-1.2	-1.2	-1.1	-0.9	-1.1	-0.5	-0.6	-0.4
Age started oral contraceptive pill	0.6	0.8	3.8	-0.0	-0.7	-0.8	-0.9	-0.9	-1.9	-0.1	-0.4	-0.9	-0.2
Neuroticism (2016)	0.5	0.8	3.6	0.3	-0.9	-0.9	-0.3	0.8	-1.9	0.0	-0.1	-1.0	-0.9
Average weekly spirits intake	0.5	0.7	2.5	-0.3	-1.0	-1.6	-0.2	-0.6	-1.2	-0.5	-0.5	-0.8	-0.7
Relative age of first facial hair	0.5	0.9	4.2	0.5	-0.2	-0.5	2.0	-1.3	-1.4	-0.7	-0.8	-0.0	0.3
Medication for hormone replacement therapy	0.5	0.6	3.6	-0.5	0.5	0.3	0.2	-0.6	1.9	0.1	-0.5	-0.6	-0.4
Medication: Metformin	0.5	0.7	2.8	0.7	-0.3	0.5	-0.7	0.7	-1.7	0.8	0.8	0.9	0.6
Number of incorrect matches in round	0.5	0.8	2.3	1.5	0.6	0.4	1.5	-0.6	0.8	-0.8	-0.1	0.1	1.2
Hearing difficulty/problems with background noise	0.5	0.8	1.7	-1.0	-0.6	-1.1	0.1	-1.0	-0.4	-0.8	-0.7	-1.0	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.0	1.2	1.5	1.7	1.7	-0.6	-0.3	0.5	0.1	0.7	1.1
Heart attack	0.5	0.6	1.5	-0.2	-0.6	-0.4	-1.0	-1.2	-0.7	-0.2	-0.6	-1.0	-1.1
Time employed in main current job	0.5	0.5	1.6	0.7	-0.6	-0.3	-0.3	-0.7	-1.1	-1.2	0.2	0.6	0.9
Length of working week for main job	0.5	0.6	1.2	-0.8	0.6	0.4	0.8	0.0	0.9	-0.9	-0.6	-1.1	-1.0
Pulse wave reflection index	0.5	0.6	2.5	0.4	0.9	0.4	1.6	-0.5	0.7	0.7	-0.2	0.6	1.0
Medication: Amlodipine	0.5	0.7	1.9	1.2	1.0	1.4	0.9	0.6	-0.7	0.8	0.4	-0.1	0.5
Worry too long after embarrassment	0.5	0.8	3.5	0.0	-0.8	-0.1	-1.5	1.9	1.0	0.5	-0.0	-0.6	-0.6
Had major operations	0.5	0.6	2.7	1.0	0.5	0.5	0.2	0.3	-0.5	1.6	0.9	0.7	0.8
Diabetes diagnosed by doctor	0.5	0.8	6.5	0.7	0.1	0.4	-0.1	0.2	-2.5	0.6	0.6	0.5	0.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.9	-0.1	-1.4	-0.4	-0.5	0.4	-0.9	0.7	-0.3	-0.9	-1.1
Illnesses of father: High blood pressure	0.5	0.6	1.0	-1.0	0.1	-0.4	0.7	-0.8	0.7	-0.8	-0.9	-1.0	-0.8
Ever smoked	0.5	0.9	3.2	0.7	1.3	0.5	1.2	-0.5	1.8	-0.0	-0.7	0.3	0.9
Risk taking	0.5	0.7	2.0	-0.4	1.4	0.7	0.8	0.8	1.0	0.9	0.8	0.6	-0.1
Alcohol drinker status: Previous	0.5	0.6	1.9	-0.5	1.0	0.5	1.1	-1.4	0.5	-0.2	-0.7	0.2	-0.1
Depressed Affect (Nagel 2018)	0.4	0.7	3.0	0.6	1.3	0.5	1.7	-0.6	-0.6	-0.4	0.6	0.7	0.7
Crohns Disease (2017)	0.4	0.9	2.3	0.3	-0.6	-0.8	-0.4	-1.5	-1.0	-1.1	-1.4	-1.0	-0.2
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.5	0.1	0.7	1.1	-0.5	0.7	1.6	0.5	0.9	1.6	0.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.8	-0.1	0.9	0.4	1.0	-1.2	0.4	-1.3	-0.3	-0.5	-0.1
Diabetes (mother)	0.4	0.5	1.1	0.7	-0.8	-0.3	0.3	0.8	-1.1	0.1	1.1	0.9	0.5
Impedance of leg (right)	0.4	1.7	8.6	0.3	0.2	0.2	-0.8	2.9	2.1	0.9	1.5	0.2	0.1
Hand grip strength (right)	0.4	1.0	3.1	0.4	0.5	0.6	-0.5	1.8	1.4	1.6	1.1	0.5	0.3
Past tobacco smoking	0.4	0.8	2.8	0.3	0.1	0.7	0.0	1.7	-0.7	1.2	1.5	0.7	0.3
Alcohol usually taken with meals	0.4	0.7	1.7	-1.3	-0.3	-0.5	-0.9	-0.8	-0.4	-0.1	-0.8	-1.2	-0.8
Qualifications: None of the above	0.4	0.9	2.4	-0.3	-0.8	-1.1	0.4	-1.1	-1.6	-1.4	-0.8	-0.5	-0.3
Allergy	0.4	1.0	2.2	-0.4	-1.5	-1.3	-0.8	-1.0	-1.4	-1.2	-0.6	-0.5	-0.9
Worrier / anxious feelings	0.4	0.8	1.8	-1.1	-0.6	-1.0	-0.8	-0.2	-0.6	-1.0	-0.3	-1.2	-1.3
Pulse rate	0.4	0.7	2.4	-0.2	-1.0	-1.5	0.2	0.3	-0.4	-1.4	0.6	-0.4	-0.8
Noisy workplace	0.4	0.5	2.1	-0.4	0.2	-0.3	1.3	-0.7	-0.5	-1.4	-0.3	0.0	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.6	-0.1	0.3	-0.0	0.2	-1.6	0.2	-0.8	-0.8	-0.5	-0.1
Lung cancer (father)	0.4	0.5	1.4	0.7	0.6	1.0	-0.2	0.9	0.5	0.3	1.2	0.5	0.6
Glaucoma (self-reported)	0.4	0.5	1.1	1.0	0.7	0.7	-0.0	0.3	0.2	0.8	0.7	0.5	1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.7	-0.0	-0.6	0.0	0.1	-1.3	-0.8	-0.5	-1.0	-0.9	-0.2
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.5	-0.0	0.3	0.2	1.2	-0.5	0.4	-0.1	-1.1	-1.1	-0.3
Wheeze or whistling in the chest in last year	0.4	0.7	1.4	-0.7	-1.2	-0.1	-1.1	-0.8	-0.8	0.2	-1.0	-0.9	-0.6
Shortness of breath walking on level ground	0.4	0.5	1.4	0.8	-0.9	-0.1	-0.9	0.8	-0.8	-0.2	1.2	-0.0	-0.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.9	-1.0	-0.8	-0.2	-1.4	-0.4	0.2	0.2	-0.3	-0.2	-0.9
Supplements: Vitamin C	0.4	0.4	1.5	-0.3	-0.2	-0.4	-1.1	1.2	0.4	-0.8	0.7	0.0	-0.1
Hypertension (Self-reported)	0.4	1.0	2.7	-0.5	0.8	0.7	1.5	-0.7	-0.5	-0.5	-1.5	-1.6	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.3	1.0	0.5	0.5	0.1	0.5	0.2	0.4	1.1	1.2	1.1
Back pain experienced in last month	0.4	0.6	2.3	0.4	-1.0	-0.6	-1.5	-0.1	-1.3	-0.6	0.1	-0.1	0.2
Mineral and other dietary supplements	0.4	0.6	2.4	1.0	0.7	0.3	1.5	-0.3	-0.1	-0.4	0.3	0.4	1.0
Guilty feelings	0.4	0.6	2.4	-0.4	0.1	0.2	-1.5	0.9	1.2	0.4	0.9	0.3	-0.4
Medication: Blood pressure	0.4	0.8	3.5	0.4	0.9	1.0	1.9	0.0	-0.7	0.4	-0.7	-1.0	-0.3
Number of operations (self-reported)	0.4	0.7	1.8	0.6	1.0	1.0	1.3	0.7	0.4	0.4	1.0	0.8	0.1
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.6	0.5	0.6	0.6	1.6	0.6	0.0	0.3	-0.2	-0.4	0.1
Fractured/broken bones in last 5 years	0.4	0.5	1.7	-0.9	0.3	0.1	0.4	0.7	-0.7	-0.8	0.2	-0.5	-1.3
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.1	0.3	-0.8	-0.9	-1.2	0.9	0.8	0.2	1.7	1.8	0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.9	-0.0	-0.7	-0.4	-1.0	-0.9	-0.7	-0.0	-0.4	-0.9	-1.0
Coronary Artery Disease (CAD)	0.3	0.4	0.7	0.7	-0.5	-0.5	-0.5	0.2	-0.0	0.6	0.9	0.8	0.7
Mean Putamen Volume	0.3	0.3	1.1	-0.4	1.1	0.8	1.0	-0.1	-0.0	-0.2	-0.4	-0.3	-0.1
Fasting Glucose	0.3	0.3	1.3	-0.2	0.4	1.1	0.3	0.6	0.4	0.0	-1.1	-0.4	0.1
HbA1C	0.3	0.3	1.1	0.6	-0.7	-0.4	-1.0	-0.6	-0.3	0.5	-0.2	0.3	0.7
LDL Cholesterol	0.3	0.5	2.1	0.4	-1.0	-0.6	-0.7	-1.0	-1.4	-0.0	-0.1	-0.2	0.0
Systolic Blood Pressure	0.3	1.7	4.7	0.7	2.0	2.2	1.6	0.4	1.9	0.8	0.3	0.3	0.9
Cardiovascular Disease	0.3	1.1	3.9	0.6	1.6	1.6	2.0	0.1	-0.7	-0.1	-0.1	0.4	0.7
Ever had hysterectomy (womb removed)	0.3	0.4	1.8	0.0	-1.0	-1.3	0.1	0.0	-0.2	-0.6	0.5	0.0	-0.3
High blood pressure	0.3	0.9	2.3	-0.4	0.9	0.9	1.5	-0.5	-0.1	-0.1	-1.4	-1.5	-0.8
Impedance of leg (left)	0.3	1.4	8.2	-0.2	-0.4	-0.3	-1.0	2.9	1.6	0.7	0.8	-0.7	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.8	0.0	0.6	-0.0	0.9	-1.3	0.2	-1.0	0.2	-0.0	-0.2
Fluid intelligence score	0.3	0.6	4.0	-0.3	0.7	0.7	-0.1	0.0	2.0	0.4	0.1	0.9	0.7
Happiness	0.3	0.4	1.6	0.7	0.4	0.4	-0.2	0.1	0.7	1.3	0.7	0.3	0.3
Asthma	0.3	0.6	1.7	0.4	0.3	1.0	-1.1	0.5	1.3	1.0	0.4	0.3	0.9
Depression (self-reported)	0.3	0.4	1.0	-0.2	-0.6	-0.7	0.3	-0.7	-0.0	-0.3	-1.0	-0.9	-0.7
Illnesses of mother	0.3	0.4	1.9	0.7	-0.9	-0.5	-1.4	-0.1	0.1	-0.1	-0.2	0.0	0.5
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	-0.3	-0.7	-0.9	0.3	-0.2	0.2	-0.9	-0.4	-0.6	-0.5
Medication: Paracetamol	0.3	0.5	1.7	-0.4	-1.0	-0.5	-1.3	0.6	-0.6	-0.4	0.9	0.6	-0.1
Health satisfaction	0.3	0.4	1.3	1.1	0.3	0.4	0.3	-0.6	-0.4	1.1	-0.1	-0.1	0.4
Qualifications: College or University degree	0.3	1.0	2.8	0.4	1.3	1.3	0.6	1.1	1.7	1.4	0.2	0.2	0.2
Eye problems/disorders: None of the above	0.3	0.3	1.3	0.4	-0.1	0.3	0.6	0.2	1.1	-1.0	0.4	0.3	-0.0
Medication for pain relief, constipation, heartburn	0.3	0.5	3.4	0.3	0.6	0.6	0.1	-0.3	1.8	0.9	-0.1	0.3	0.5
Family relationship satisfaction	0.3	0.4	1.4	-0.2	-0.0	-0.5	-1.2	0.4	-0.5	0.9	0.8	-0.1	-0.3
Illnesses of siblings: Diabetes	0.3	0.4	1.1	1.0	-0.1	0.2	0.0	0.6	-0.1	0.9	0.6	0.7	0.8
Mood swings	0.3	0.6	4.7	0.2	0.5	0.0	-0.5	-0.8	-2.2	0.2	-0.0	0.3	0.2
Friendships satisfaction	0.3	0.3	1.0	-0.4	-0.0	-1.0	-0.7	-0.8	-0.7	0.0	-0.4	-0.4	-0.3
Commuting to job workplace: Walk	0.3	0.4	1.4	-0.6	-0.4	-0.3	-0.9	-1.2	-0.6	-0.6	-0.2	-0.1	-0.3
Medication for cholesterol	0.3	0.4	1.7	-0.2	-0.0	-0.6	-1.3	0.3	0.4	0.0	0.7	1.1	0.5
Average weekly champagne plus white wine intake	0.3	0.4	1.1	0.1	0.4	-0.1	1.0	-0.5	0.5	-0.6	-1.0	-0.9	0.1
Miserableness	0.3	0.5	1.6	0.3	1.2	0.8	1.0	-0.4	0.8	-0.3	0.2	0.4	0.3
Medication: Atorvastatin	0.3	0.3	0.9	0.0	0.1	0.6	0.1	-0.7	-1.0	-0.5	-0.8	-0.5	-0.4
Alzheimer’s Disease (including proxy)	0.2	0.4	0.9	-0.5	-0.4	-0.5	-0.4	-1.0	-0.8	-0.6	-0.2	-0.6	-0.5
Breast Cancer	0.2	0.5	2.9	-0.0	-0.2	0.2	-0.5	-1.7	-0.4	0.4	-1.0	-0.8	-0.3
Heel T-Score	0.2	1.5	3.1	1.8	0.7	1.1	1.7	-1.2	-1.4	0.8	0.1	0.9	1.6
Lung FEV1/FVC ratio	0.2	1.2	5.5	-0.5	-0.6	-0.8	-1.5	2.3	0.9	0.1	1.3	0.6	-0.2
Number of treatments/medications taken	0.2	0.4	3.0	-0.1	-0.3	0.2	-0.4	-0.7	-1.7	-0.4	-0.5	-0.4	-0.0
Current tobacco smoking	0.2	0.3	2.0	-0.3	0.4	0.1	1.4	-0.2	0.1	-0.4	-0.4	-0.4	0.0
Relative age voice broke	0.2	0.3	2.1	0.7	0.1	0.2	1.5	-0.3	0.0	0.3	0.4	0.3	0.5
Supplements: Glucosamine	0.2	0.3	1.2	-0.7	0.1	0.1	-1.1	0.7	0.6	0.2	0.2	0.3	-0.3
Had other major operations	0.2	0.2	1.0	0.4	0.1	-0.0	0.4	0.4	0.3	-0.3	1.0	0.5	0.2
Trunk fat-free mass	0.2	1.0	3.3	0.6	0.9	0.6	0.5	-0.9	1.8	-0.4	0.6	1.3	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.9	-0.2	-0.2	-0.2	0.5	-0.9	-0.5	-0.9	-0.8	-0.6	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.6	0.4	0.2	0.3	-0.2	0.7	1.3	0.3	0.2	-0.1	0.2
Pulse wave Arterial Stiffness index	0.2	0.3	0.6	0.8	0.3	0.3	0.3	0.6	0.8	0.5	0.4	0.0	0.7
Trunk predicted mass	0.2	1.0	3.3	0.6	0.9	0.6	0.5	-0.9	1.8	-0.4	0.7	1.3	1.1
Birth weight of first child	0.2	0.4	1.8	0.9	0.7	0.5	1.3	-0.3	-0.3	0.5	-0.1	-0.3	0.1
Loud music exposure frequency	0.2	0.2	1.3	0.4	-0.3	-0.2	-1.1	-0.1	0.5	0.8	0.0	-0.1	0.3
Birth weight	0.2	0.4	1.2	-0.7	-0.4	-1.1	-0.1	-0.6	-0.8	-0.4	0.2	-0.6	-0.8
Arm fat-free mass (right)	0.2	0.8	4.5	-0.3	-0.3	-0.7	0.2	-2.1	-0.3	-1.6	-0.6	-0.1	-0.1
Emphysema/chronic bronchitis	0.2	0.2	0.5	-0.5	-0.1	0.5	0.0	-0.0	0.5	-0.3	-0.5	-0.6	-0.7
Medication: Seretide 50 evohaler	0.2	0.2	0.9	0.2	0.4	0.5	-0.2	0.0	0.6	0.4	1.0	0.5	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.6	0.3	-0.0	0.6	0.3	0.7	0.1	-0.5	0.2	-0.5	-0.3
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.0	0.3	0.6	0.6	-0.3	0.3	-0.3	1.0	0.2	0.3	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.2	-0.1	0.2	0.4	-0.0	-0.1	1.1	-0.4	-0.3	-0.5	-0.3
Asthma (self-reported)	0.2	0.4	1.8	0.1	0.0	0.8	-1.4	0.1	1.0	0.8	-0.1	-0.2	0.5
Illnesses of father: None of the above (group 1)	0.2	0.2	1.1	-0.4	-0.1	0.1	-0.4	-1.1	0.4	0.1	-0.5	0.0	-0.2
Smoking status: Current	0.2	0.3	2.5	-0.1	0.5	0.1	1.6	-0.2	0.2	-0.0	-0.1	0.0	0.3
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.2	0.3	0.7	0.6	0.9	0.5	0.7	-0.3	-0.6	-0.5
Diastolic blood pressure, automated reading	0.2	0.7	1.5	0.8	0.8	1.2	1.2	0.9	0.2	1.0	0.7	0.7	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.8	0.4	0.0	0.2	-0.7	-0.5	0.8	0.1	-0.2	0.8	0.9
Neuroticism (Nagel 2018)	0.1	0.2	0.6	-0.3	0.6	0.1	0.3	-0.3	-0.8	-0.5	-0.3	-0.2	-0.0
Major Depression (MDD)	0.1	0.2	0.7	0.4	-0.5	-0.8	0.4	0.1	0.0	-0.4	-0.2	-0.2	-0.1
Bipolar Disorder (2011)	0.1	0.1	0.6	-0.2	0.0	-0.2	0.0	-0.1	0.0	-0.2	-0.4	-0.8	-0.5
Crohns Disease (2012)	0.1	0.2	0.7	-0.2	0.0	-0.4	0.0	-0.7	-0.1	-0.4	-0.8	-0.8	-0.3
Blood Eosinophil Count	0.1	1.0	2.7	1.4	0.7	0.8	-0.0	1.3	0.7	1.6	1.1	0.8	0.6
Blood Platelet Count	0.1	0.7	2.0	1.0	-0.2	-0.2	1.1	-1.0	-1.4	-0.1	0.3	1.1	0.7
Waist Hip Ratio (WHR)	0.1	0.5	2.3	-0.1	-0.2	0.4	0.2	1.4	0.1	1.5	-0.1	-0.7	-0.6
Respiratory disease	0.1	0.3	0.7	-0.0	0.5	0.7	-0.3	-0.7	0.8	0.6	-0.4	-0.5	0.2
Chronotype (morning person)	0.1	0.3	1.7	0.4	-0.4	-0.5	0.5	0.6	-1.3	0.0	0.6	0.2	0.3
Tanning	0.1	0.9	2.6	-1.6	-1.1	-1.0	-0.3	-0.0	1.0	-0.8	-0.1	-0.9	-1.4
Systolic blood pressure, automated reading	0.1	0.2	0.5	-0.7	0.2	0.3	0.6	-0.7	-0.6	0.0	-0.3	0.0	-0.5
Diabetes (father)	0.1	0.1	0.4	0.5	0.3	0.3	0.1	-0.2	0.6	0.4	-0.2	0.4	0.2
Leg fat-free mass (left)	0.1	0.6	4.2	0.5	-0.1	-0.1	0.2	-2.0	0.2	-1.2	-0.4	0.2	0.4
Fed-up feelings	0.1	0.1	0.7	-0.3	0.4	0.1	0.0	-0.0	0.8	-0.4	0.3	0.1	-0.1
Leg predicted mass (left)	0.1	0.6	4.3	0.4	-0.2	-0.2	0.1	-2.1	0.2	-1.3	-0.4	0.2	0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.5	0.6	0.3	0.4	0.1	0.0	-0.5	0.7	0.0	-0.2	0.3
Neuroticism score	0.1	0.1	0.9	-0.2	0.2	-0.1	-1.0	-0.2	-0.3	-0.3	0.1	-0.3	-0.3
Falls in the last year	0.1	0.2	0.9	0.3	-0.5	-0.5	0.0	0.1	0.2	-1.0	0.1	-0.6	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.8	0.9	-0.1	-0.0	-0.6	0.3	0.7	0.4	0.3	-0.0	0.3
Hair/balding pattern: Pattern 4	0.1	0.3	0.6	0.8	-0.7	-0.5	-0.7	0.7	0.3	-0.3	0.3	-0.2	0.6
Comparative body size at age 10	0.1	0.2	0.5	-0.1	0.2	0.3	-0.2	0.5	0.5	0.7	0.6	0.7	0.2
Pulse wave peak to peak time	0.1	0.1	0.3	-0.6	0.0	0.1	-0.2	-0.4	-0.4	-0.4	-0.1	0.2	-0.4
Medication: Ibuprofen	0.1	0.2	0.6	0.1	0.1	0.5	-0.1	0.4	0.7	0.2	-0.4	-0.6	-0.3
Arm predicted mass (right)	0.1	0.8	3.9	-0.4	-0.4	-0.8	0.2	-2.0	-0.3	-1.5	-0.5	0.0	-0.2
Pulse rate, automated reading	0.1	0.2	0.7	-0.4	-0.1	-0.5	0.1	0.7	0.0	0.3	0.8	0.4	-0.6
Whole body fat-free mass	0.1	0.5	2.2	0.4	0.3	0.1	0.3	-1.5	0.9	-0.8	0.2	0.8	0.7
Leg fat-free mass (right)	0.1	0.5	3.6	0.4	-0.1	-0.1	0.2	-1.9	0.2	-1.1	-0.5	0.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.7	0.7	0.3	0.7	0.9	0.4	0.5	0.4	0.1	0.3	0.1
Whole body water mass	0.1	0.5	2.3	0.4	0.3	0.1	0.4	-1.5	1.0	-0.8	0.1	0.7	0.7
Leg predicted mass (right)	0.1	0.6	3.7	0.4	-0.0	-0.1	0.2	-1.9	0.3	-1.0	-0.5	0.0	0.4
Medication: Lisinopril	0.1	0.2	0.4	-0.6	0.3	0.2	0.0	-0.3	-0.2	-0.2	-0.4	-0.6	-0.6
Basal metabolic rate	0.1	0.5	3.1	0.0	-0.2	-0.4	0.2	-1.8	0.2	-1.2	-0.2	0.2	0.1
Arm fat-free mass (left)	0.1	0.6	3.3	-0.2	-0.3	-0.6	0.3	-1.8	-0.2	-1.2	-0.2	0.4	0.1
Arm predicted mass (left)	0.1	0.7	3.7	-0.3	-0.2	-0.6	0.4	-1.9	-0.1	-1.4	-0.3	0.2	-0.1
Neuroticism	0.0	0.1	0.6	0.1	0.7	0.2	-0.2	-0.1	-0.8	-0.0	0.3	-0.1	-0.1
Hair Pigment	0.0	0.3	1.2	0.6	0.0	-0.1	-0.3	0.3	-1.1	0.6	0.7	0.8	0.4

Hub : Genes

DHRS7B

Models

Trait associations