Best TWAS P=4.65e-08 · Best GWAS P=3.9e-07 conditioned to 0.668
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | RASIP1 | 0.15 | 0.04 | lasso | 6 | 0.08 | 2.9e-05 | -4.0 | -5.2 | 2.5e-07 | -0.11 | 0.21 | 0.39 | TRUE |
| 2 | GTEx | Spleen | PPFIA3 | 0.25 | 0.23 | lasso | 4 | 0.21 | 3.9e-06 | 4.6 | -5.3 | 1.1e-07 | -0.67 | 0.01 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNRNP70 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-02 | 5.1 | -5.5 | 4.6e-08 | -0.87 | 0.01 | 0.71 | TRUE |