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Traits
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Leg fat mass (left)
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chr19:48,525,507-50,349,958
Best TWAS P=4.65e-08 · Best GWAS P=3.9e-07 conditioned to 0.668
48.5M
49M
49.5M
50M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Colon Adenocarcinoma
SNRNP70
0.05
0.02
lasso
3
0.02
2.9e-02
5.1
-5.5
4.6e-08
-0.87
0.01
0.71
TRUE
1
GTEx
Skin Not Sun Exposed Suprapubic
RASIP1
0.15
0.04
lasso
6
0.08
2.9e-05
-4.0
-5.2
2.5e-07
-0.11
0.21
0.39
TRUE
2
GTEx
Spleen
PPFIA3
0.25
0.23
lasso
4
0.21
3.9e-06
4.6
-5.3
1.1e-07
-0.67
0.01
0.96
FALSE