[Hub]/) : Traits : Leg fat mass (left) : ← →

chr7:98,244,565-99,827,148

Best TWAS P=5.44e-10 · Best GWAS P=2.7e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZKSCAN5	0.03	0.04	lasso	2	0.03	1.0e-04	-6.2	-6.2	5.4e-10	0.98	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	CPSF4	0.06	0.06	blup	313	0.07	6.6e-09	-6.3	-5.7	9.6e-09	0.90	0.01	0.99	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	GS1-259H13.2	0.07	0.05	bslmm	305	0.06	6.9e-08	-5.6	5.7	1.3e-08	-0.81	0.22	0.78	FALSE
8	GTEx	Thyroid	GS1-259H13.2	0.26	0.05	enet	30	0.08	7.6e-07	-5.4	5.6	1.6e-08	-0.59	0.56	0.40	FALSE
3	GTEx	Cells Transformed fibroblasts	CPSF4	0.08	0.03	lasso	4	0.03	1.8e-03	-5.5	-5.6	2.2e-08	0.77	0.19	0.54	FALSE
9	METSIM	Adipose	ARPC1A	0.02	0.02	blup	308	0.02	1.6e-03	-4.4	-5.6	2.5e-08	0.85	0.06	0.89	FALSE
4	GTEx	Esophagus Mucosa	GS1-259H13.2	0.07	0.07	lasso	3	0.05	1.7e-04	-5.4	5.5	3.3e-08	-0.78	0.26	0.63	FALSE
5	GTEx	Lung	ZKSCAN5	0.09	0.05	lasso	2	0.03	2.7e-03	-5.5	5.5	4.1e-08	-0.75	0.28	0.38	FALSE
10	METSIM	Adipose	GS1-259H13.2	0.04	0.03	lasso	3	0.02	1.4e-03	-5.4	5.5	4.9e-08	-0.74	0.19	0.78	FALSE
6	GTEx	Lung	GS1-259H13.2	0.09	0.07	lasso	4	0.05	8.4e-05	-5.4	5.4	6.6e-08	-0.74	0.51	0.39	FALSE
2	GTEx	Adipose Visceral Omentum	GS1-259H13.2	0.23	0.12	lasso	1	0.09	1.8e-05	-5.3	5.3	1.0e-07	-0.75	0.59	0.34	FALSE
7	GTEx	Nerve Tibial	GS1-259H13.2	0.15	0.10	lasso	4	0.09	3.4e-07	-5.4	5.3	1.0e-07	-0.73	0.62	0.37	FALSE