[Hub]/) : Traits : Leg fat mass (left) : ← →

chr7:98,244,565-99,827,148

Best TWAS P=5.44e-10 · Best GWAS P=2.7e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CPSF4 0.06 0.06 blup 313 0.07 6.6e-09 -6.3 -5.7 9.6e-09 0.90 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum GS1-259H13.2 0.23 0.12 lasso 1 0.09 1.8e-05 -5.3 5.3 1.0e-07 -0.75 0.59 0.34 FALSE
3 GTEx Cells Transformed fibroblasts CPSF4 0.08 0.03 lasso 4 0.03 1.8e-03 -5.5 -5.6 2.2e-08 0.77 0.19 0.54 FALSE
4 GTEx Esophagus Mucosa GS1-259H13.2 0.07 0.07 lasso 3 0.05 1.7e-04 -5.4 5.5 3.3e-08 -0.78 0.26 0.63 FALSE
5 GTEx Lung ZKSCAN5 0.09 0.05 lasso 2 0.03 2.7e-03 -5.5 5.5 4.1e-08 -0.75 0.28 0.38 FALSE
6 GTEx Lung GS1-259H13.2 0.09 0.07 lasso 4 0.05 8.4e-05 -5.4 5.4 6.6e-08 -0.74 0.51 0.39 FALSE
7 GTEx Nerve Tibial GS1-259H13.2 0.15 0.10 lasso 4 0.09 3.4e-07 -5.4 5.3 1.0e-07 -0.73 0.62 0.37 FALSE
8 GTEx Thyroid GS1-259H13.2 0.26 0.05 enet 30 0.08 7.6e-07 -5.4 5.6 1.6e-08 -0.59 0.56 0.40 FALSE
9 METSIM Adipose ARPC1A 0.02 0.02 blup 308 0.02 1.6e-03 -4.4 -5.6 2.5e-08 0.85 0.06 0.89 FALSE
10 METSIM Adipose GS1-259H13.2 0.04 0.03 lasso 3 0.02 1.4e-03 -5.4 5.5 4.9e-08 -0.74 0.19 0.78 FALSE
11 ROSMAP Brain Pre-frontal Cortex GS1-259H13.2 0.07 0.05 bslmm 305 0.06 6.9e-08 -5.6 5.7 1.3e-08 -0.81 0.22 0.78 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma ZKSCAN5 0.03 0.04 lasso 2 0.03 1.0e-04 -6.2 -6.2 5.4e-10 0.98 0.01 0.99 TRUE