[Hub]/) : Traits : Leg fat mass (left) : ← →

chr10:103,718,818-105,647,095

Best TWAS P=7.35e-09 · Best GWAS P=3.09e-08 conditioned to 0.00602

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Brain Cerebellum	ARL3	0.20	0.09	enet	32	0.07	3.7e-03	5.2	5.8	7.3e-09	0.57	0.05	0.87	TRUE
8	The Cancer Genome Atlas	Thyroid Carcinoma	CYP17A1	0.04	0.02	lasso	1	0.02	3.9e-03	5.5	-5.5	3.1e-08	-1.00	0.01	0.90	FALSE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	AS3MT	0.06	0.09	enet	6	0.07	1.3e-06	5.0	-5.5	4.7e-08	-0.80	0.05	0.95	FALSE
2	GTEx	Artery Tibial	CYP17A1-AS1	0.08	0.08	lasso	8	0.06	2.8e-05	5.3	5.4	8.5e-08	0.95	0.02	0.98	FALSE
5	GTEx	Nerve Tibial	CYP17A1-AS1	0.14	0.08	lasso	6	0.06	7.2e-05	5.1	5.3	9.1e-08	0.82	0.04	0.94	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	CYP17A1-AS1	0.15	0.18	lasso	6	0.19	1.3e-23	5.2	5.3	9.2e-08	0.81	0.04	0.96	FALSE
4	GTEx	Brain Cerebellum	TRIM8	0.34	-0.01	enet	25	0.07	4.7e-03	-2.3	-5.3	1.3e-07	-0.46	0.06	0.36	FALSE
1	GTEx	Artery Tibial	NT5C2	0.06	0.04	lasso	9	0.02	1.5e-02	5.3	-5.2	1.7e-07	-0.95	0.03	0.93	FALSE