[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr12:109,231,851-113,517,494

Best TWAS P=9.66e-11 · Best GWAS P=1.46e-15 conditioned to 0.00775

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	-7.2	-6.5	9.7e-11	0.85	0.02	0.92	TRUE
13	NTR	Blood	UBE3B	0.09	0.05	lasso	8	0.08	1.0e-25	5.1	6.0	1.9e-09	0.02	0.03	0.97	TRUE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	CUX2	0.08	0.01	blup	95	0.02	1.3e-03	4.2	5.8	7.3e-09	-0.16	0.02	0.76	TRUE
2	GTEx	Artery Tibial	VPS29	0.05	0.03	lasso	3	0.02	5.9e-03	5.4	5.4	5.8e-08	-0.07	0.01	0.96	TRUE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	MMAB	0.06	0.06	blup	57	0.06	5.4e-07	-5.1	-6.0	2.4e-09	-0.03	0.09	0.91	FALSE
12	NTR	Blood	ALDH2	0.06	0.01	blup	222	0.02	4.3e-08	4.3	5.9	4.2e-09	-0.60	0.37	0.62	FALSE
7	GTEx	Colon Sigmoid	KCTD10	0.25	0.16	lasso	8	0.15	6.2e-06	5.3	-5.7	1.5e-08	-0.03	0.08	0.90	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	KCTD10	0.06	0.00	lasso	3	0.00	1.4e-01	5.1	-5.5	4.0e-08	-0.05	0.01	0.68	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	MMAB	0.40	0.24	enet	16	0.28	2.5e-08	4.9	-5.5	4.6e-08	-0.01	0.07	0.82	FALSE
4	GTEx	Brain Cerebellar Hemisphere	MMAB	0.31	0.27	lasso	3	0.24	6.6e-07	5.4	-5.5	4.9e-08	-0.06	0.02	0.98	FALSE
8	GTEx	Colon Transverse	MMAB	0.08	0.07	lasso	2	0.05	1.7e-03	5.3	-5.4	7.7e-08	-0.04	0.09	0.77	FALSE
1	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	4.6	5.3	9.0e-08	-0.19	0.03	0.12	FALSE
11	GTEx	Thyroid	VPS29	0.07	0.01	lasso	5	0.01	8.9e-02	4.5	5.3	1.1e-07	-0.06	0.01	0.87	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MMAB	0.04	0.02	blup	53	0.02	5.2e-03	5.3	-5.3	1.1e-07	-0.05	0.02	0.54	FALSE
9	GTEx	Esophagus Muscularis	KCTD10	0.21	0.19	lasso	6	0.17	1.3e-10	4.9	-5.2	2.3e-07	0.00	0.21	0.78	FALSE
10	GTEx	Muscle Skeletal	VPS29	0.06	0.06	lasso	3	0.05	4.3e-06	5.4	5.2	2.5e-07	-0.04	0.00	0.99	FALSE
6	GTEx	Breast Mammary Tissue (Female)	VPS29	0.10	-0.01	lasso	2	0.02	1.0e-01	-3.9	5.1	2.7e-07	-0.24	0.02	0.30	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	KCTD10	0.27	0.20	lasso	1	0.18	4.5e-06	5.1	-5.1	2.9e-07	-0.06	0.01	0.98	FALSE