Best TWAS P=7.37e-08 · Best GWAS P=1.94e-06 conditioned to 0.25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | AP2A1 | 0.18 | 0.09 | enet | 8 | 0.13 | 7.7e-09 | -4.1 | -5.2 | 2.2e-07 | 0.01 | 0.01 | 0.90 | TRUE |
| 2 | GTEx | Testis | NTN5 | 0.16 | 0.02 | enet | 23 | 0.06 | 9.6e-04 | -2.5 | -5.3 | 9.8e-08 | 0.16 | 0.03 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LIN7B | 0.02 | 0.00 | enet | 7 | 0.02 | 5.1e-05 | 4.4 | -5.3 | 9.5e-08 | 0.73 | 0.01 | 0.80 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNRNP70 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-02 | 4.3 | -5.4 | 7.4e-08 | 0.76 | 0.01 | 0.44 | TRUE |