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Traits
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Traits
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Leg fat-free mass (left)
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chr19:48,464,978-51,004,754
Best TWAS P=7.37e-08 · Best GWAS P=1.94e-06 conditioned to 0.25
48.5M
49M
49.5M
50M
50.5M
51M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Colon Adenocarcinoma
SNRNP70
0.05
0.02
lasso
3
0.02
2.9e-02
4.3
-5.4
7.4e-08
0.76
0.01
0.44
TRUE
2
GTEx
Testis
NTN5
0.16
0.02
enet
23
0.06
9.6e-04
-2.5
-5.3
9.8e-08
0.16
0.03
0.10
TRUE
1
GTEx
Esophagus Mucosa
AP2A1
0.18
0.09
enet
8
0.13
7.7e-09
-4.1
-5.2
2.2e-07
0.01
0.01
0.90
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
LIN7B
0.02
0.00
enet
7
0.02
5.1e-05
4.4
-5.3
9.5e-08
0.73
0.01
0.80
FALSE