TWAS hub - AP2A1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0300	4.6e-03	-0.002	0.018	0.021	0.013	0.007	7.6e-01	2.6e-03	1.1e-03	0.0089	4.1e-02
2	GTEx	Brain Cerebellar Hemisphere	0.3250	0.1050	1.3e-03	0.052	NA	0.014	NA	0.062	1.9e-02	NA	1.4e-01	NA	1.1e-02
3	GTEx	Brain Cerebellum	0.2290	0.0860	6.5e-03	-0.007	NA	-0.010	NA	-0.010	6.0e-01	NA	8.5e-01	NA	9.2e-01
4	GTEx	Esophagus Mucosa	0.1760	0.0490	4.8e-06	0.092	NA	0.127	NA	0.119	9.6e-07	NA	7.7e-09	NA	2.3e-08
5	GTEx	Nerve Tibial	0.1612	0.0529	1.2e-04	0.050	NA	0.052	NA	0.069	1.8e-04	NA	1.4e-04	NA	1.4e-05
6	GTEx	Skin Sun Exposed Lower leg	0.1530	0.0420	1.1e-05	0.080	NA	0.070	NA	0.063	3.5e-07	NA	1.9e-06	NA	6.4e-06
7	TCGA	Breast Invasive Carcinoma	0.0385	0.0161	7.1e-07	0.035	0.036	0.037	NA	0.039	1.0e-07	7.0e-08	4.4e-08	NA	1.8e-08
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0880	0.0450	3.0e-03	0.052	0.024	0.039	NA	0.045	5.8e-04	1.5e-02	2.7e-03	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Trunk predicted mass	5.5	31.2	49.0	-3.8	-5.0	-4.2	-7.0	-7.0	-6.2	6.0	4.5
Trunk fat-free mass	5.4	31.2	48.6	-3.7	-5.0	-4.2	-7.0	-6.9	-6.2	6.0	4.6
Impedance of whole body	5.2	26.2	48.7	4.2	2.4	4.0	6.7	7.0	5.0	-5.6	-4.6
Whole body fat-free mass	4.8	27.2	43.0	-3.8	-4.5	-4.1	-6.6	-6.5	-5.7	5.5	4.4
Whole body water mass	4.8	27.6	43.1	-3.8	-4.5	-4.1	-6.6	-6.5	-5.8	5.5	4.4
Relative age voice broke	4.7	7.2	12.4	1.9	2.2	2.0	3.5	2.9	3.1	-2.8	-2.6
Mouth/teeth dental problems	4.7	7.2	10.7	-1.7	-2.7	-2.6	-3.0	-2.6	-3.3	2.5	2.8
Arm predicted mass (left)	4.7	24.1	40.6	-4.0	-4.0	-3.6	-6.3	-6.4	-5.2	5.0	3.9
Impedance of arm (right)	4.6	21.4	42.5	4.1	1.7	3.7	6.2	6.5	4.6	-4.8	-3.7
Impedance of arm (left)	4.6	21.1	42.1	4.2	2.1	3.2	6.1	6.5	4.6	-4.9	-3.6
Arm predicted mass (right)	4.6	23.5	38.4	-3.9	-4.0	-3.9	-6.1	-6.2	-5.3	4.8	3.9
Arm fat-free mass (left)	4.5	22.6	37.2	-3.7	-4.0	-3.4	-6.0	-6.1	-5.2	4.9	3.9
Medication: Lansoprazole	4.4	5.0	8.0	1.7	2.7	2.1	2.6	2.8	2.2	-2.2	-1.0
Neuroticism	4.3	10.3	17.4	1.2	2.0	4.2	3.3	3.1	4.0	-3.8	-2.9
Impedance of leg (right)	4.3	21.0	39.3	3.9	1.5	3.9	6.0	6.3	4.4	-4.9	-4.1
Arm fat-free mass (right)	4.3	22.0	36.2	-3.8	-3.7	-3.7	-5.9	-6.0	-5.1	4.7	3.9
Migraine (self-reported)	4.1	5.1	12.5	-1.4	-1.0	-1.8	-3.3	-3.5	-1.9	2.3	1.5
Basal metabolic rate	3.9	21.4	33.7	-3.4	-3.9	-3.6	-5.8	-5.8	-5.0	4.9	4.0
Eye problems/disorders: Diabetes related eye disease	3.8	4.1	6.3	-0.1	2.3	1.7	2.5	1.8	2.5	-2.1	-2.1
Mouth/teeth dental problems: Dentures	3.7	6.2	13.0	1.2	1.7	2.6	2.7	2.4	3.6	-2.8	-2.2
Leg fat-free mass (right)	3.7	19.6	31.9	-3.3	-3.4	-3.7	-5.6	-5.6	-4.7	4.5	3.8
Leg predicted mass (right)	3.7	19.8	32.1	-3.3	-3.5	-3.7	-5.7	-5.6	-4.8	4.5	3.8
Illnesses of father: High blood pressure	3.7	4.6	8.6	-1.2	-1.6	-2.6	-2.9	-2.2	-2.4	2.1	1.6
Impedance of leg (left)	3.6	17.7	32.0	3.5	1.6	3.2	5.6	5.7	3.9	-4.7	-4.1
Current tobacco smoking	3.3	5.3	8.0	-2.2	-2.0	-2.4	-2.8	-2.8	-2.2	2.3	1.5
Ever had prostate specific antigen (PSA) test	3.3	3.8	5.5	-1.1	-1.7	-2.3	-2.0	-2.0	-1.8	2.3	1.9
Leg predicted mass (left)	3.2	16.7	26.6	-3.0	-3.5	-3.3	-5.2	-5.0	-4.3	4.2	3.8
Depression (self-reported)	3.2	3.8	7.9	1.0	2.1	1.3	2.0	1.7	2.8	-2.2	-1.8
Leg fat-free mass (left)	3.1	16.6	26.8	-3.1	-3.5	-3.2	-5.2	-5.1	-4.3	4.1	3.7
Age at First Birth	3.0	4.4	7.6	0.7	1.9	2.5	1.9	1.9	1.8	-2.8	-2.6
Smoking status: Current	3.0	4.8	7.2	-2.2	-2.1	-2.2	-2.7	-2.5	-2.2	2.1	1.3
Pulse wave reflection index	2.8	3.5	5.2	-1.4	-1.9	-1.5	-2.1	-1.8	-2.0	2.3	1.6
Average weekly fortified wine intake	2.7	3.2	3.9	-1.9	-1.9	-0.6	-2.0	-1.9	-1.8	2.0	1.7
Qualifications: CSEs or equivalent	2.7	3.6	6.5	-1.7	-2.2	-1.7	-2.0	-2.5	-1.4	1.6	1.9
Sitting height	2.7	19.0	29.2	-2.7	-5.4	-2.8	-5.2	-5.0	-5.3	4.4	2.9
Pulse wave Arterial Stiffness index	2.7	3.1	5.5	-1.4	-1.4	-1.1	-2.1	-1.8	-1.5	2.1	2.4
Exposure to tobacco smoke at home	2.7	3.0	5.1	-0.5	1.1	1.2	1.9	2.0	2.1	-1.9	-2.2
Peak expiratory flow (PEF)	2.5	5.9	10.7	0.0	-3.0	-1.6	-3.1	-2.8	-3.3	2.5	1.1
Pulse wave peak to peak time	2.5	3.0	5.5	1.6	1.2	1.1	2.0	1.7	1.4	-2.0	-2.4
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.2	21.2	-1.8	-4.6	-1.0	-2.0	-1.9	-2.2	1.8	0.9
Qualifications: O levels/GCSEs or equivalent	2.4	3.8	8.0	-1.1	-1.6	-1.6	-2.4	-2.6	-1.3	1.6	2.8
Chronic bronchitis/emphysema (mother)	2.4	2.8	6.5	-0.5	1.5	1.5	1.6	1.4	2.5	-2.0	-1.7
Fed-up feelings	2.3	4.1	10.8	2.0	1.3	3.3	1.6	1.6	1.9	-1.5	-2.3
Had menopause	2.3	2.8	6.1	0.6	2.2	1.5	1.8	2.5	1.5	-1.7	-0.8
Worry too long after embarrassment	2.3	3.9	8.0	0.7	1.1	2.8	2.1	2.0	2.4	-2.2	-1.6
Worry (Nagel 2018)	2.2	4.6	8.5	0.5	0.2	2.3	2.9	2.5	2.9	-2.5	-1.5
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.5	6.9	0.5	0.2	2.6	2.4	2.2	1.9	-1.9	-1.7
Mouth/teeth dental problems: Loose teeth	2.2	2.6	4.4	0.7	0.5	1.8	1.9	2.0	2.1	-2.0	-0.8
Mean time to correctly identify matches	2.2	4.2	7.7	2.3	2.8	2.0	2.1	2.6	1.4	-1.4	-1.2
Guilty feelings	2.2	3.3	5.3	1.8	0.4	2.3	2.1	2.0	1.5	-1.7	-2.2
Medication: Ibuprofen	2.0	2.4	5.4	0.4	-1.5	0.0	-1.8	-2.2	-1.7	2.3	0.6
Medication: Co-codamol	1.9	2.2	8.0	0.5	2.8	1.8	1.3	0.8	1.8	-0.8	-0.1
Medication: Metformin	1.9	2.7	5.6	-0.8	1.7	1.4	1.3	1.7	2.2	-2.4	-1.1
Medication: Ramipril	1.9	2.5	4.9	0.9	0.8	2.0	2.2	1.7	2.1	-1.5	0.3
Mouth/teeth dental problems: Bleeding gums	1.9	2.4	4.7	1.4	1.0	1.5	1.7	1.5	1.5	-1.4	-2.2
Headache pain in last month	1.9	3.3	7.3	-1.1	-1.1	0.5	-2.6	-2.7	-2.1	2.2	1.0
Back pain experienced in last month	1.9	2.8	5.4	-0.5	-0.3	-1.5	-1.8	-1.9	-1.6	2.2	2.3
Neuroticism (Nagel 2018)	1.8	4.3	9.4	0.4	0.1	3.1	2.4	1.9	2.7	-2.3	-1.5
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	6.9	-0.4	-1.1	-0.3	-1.0	-0.9	-2.2	2.6	1.9
Supplements: Zinc	1.8	2.0	5.0	0.6	2.2	1.1	1.5	1.5	1.5	-1.1	-1.1
Forced vital capacity (FVC)	1.8	7.0	19.5	-0.1	-4.4	-2.2	-2.7	-2.5	-3.1	2.3	1.7
Qualifications: A levels/AS levels or equivalent	1.8	3.9	6.3	-0.7	-2.3	-1.6	-2.5	-2.5	-2.5	1.6	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	4.6	1.0	1.2	2.1	1.4	1.5	1.9	-1.4	-1.0
Length of working week for main job	1.7	1.8	3.5	-0.5	1.8	1.9	0.8	1.6	1.1	-1.2	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	5.0	1.1	2.2	0.3	1.8	1.7	1.5	-1.1	-0.4
Hearing difficulty/problems: Yes	1.5	2.3	5.4	-0.2	-1.6	-1.0	-1.7	-1.4	-2.3	1.6	1.4
Medication: Levothyroxine sodium	1.5	2.5	6.2	2.5	2.2	1.6	1.6	1.2	1.7	-0.2	0.3
Diabetes (self-reported)	1.5	2.3	3.8	-0.7	1.9	1.7	0.9	1.2	1.7	-2.0	-1.4
Forced expiratory volume in 1-second (FEV1)	1.5	5.2	12.4	0.3	-3.5	-2.2	-2.3	-2.3	-2.6	2.1	1.3
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	5.1	0.9	-1.1	0.2	-1.5	-2.1	-1.4	2.2	0.2
Leg pain on walking	1.5	1.9	4.1	0.2	-0.5	-0.8	-2.0	-2.0	-1.4	1.5	1.2
Diabetes (mother)	1.4	1.7	4.5	-0.9	-2.1	-1.1	-1.2	-1.3	-1.0	0.9	1.6
Pack years adult smoking proportion	1.4	2.1	4.0	-1.4	-1.9	-1.2	-1.9	-2.0	-0.9	0.9	0.8
Number of full brothers	1.4	1.8	3.6	-1.3	-1.9	-1.4	-1.3	-1.3	-1.5	1.1	0.4
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	6.4	-0.8	-0.4	-1.2	-1.2	-0.9	-0.9	1.4	2.5
Qualifications: nursing, teaching	1.4	2.2	3.5	-1.9	1.1	-1.8	-1.8	-1.6	-0.9	0.7	1.7
Financial situation satisfaction	1.4	1.7	3.2	1.4	1.8	0.9	0.9	1.2	1.1	-1.5	-1.6
Commuting to job workplace: Cycle	1.4	1.7	4.0	-0.5	1.5	0.7	2.0	1.9	1.3	-0.9	-0.6
Hypothyroidism (self reported)	1.3	3.0	8.1	2.9	2.6	1.1	1.6	1.5	1.8	-0.3	0.0
Relative age of first facial hair	1.3	2.8	5.2	0.2	0.9	-0.2	2.3	2.1	1.8	-2.3	-1.9
Hand grip strength (right)	1.3	3.6	6.5	-1.1	-1.4	-1.8	-2.5	-2.4	-2.4	2.0	1.0
Weight	1.3	6.3	10.4	-2.2	-1.8	-1.9	-3.2	-3.1	-2.3	2.5	2.5
Standing height	1.3	13.1	28.1	-1.2	-5.3	-2.5	-4.1	-3.4	-4.7	3.5	2.5
Forced vital capacity (FVC), Best measure	1.3	4.7	13.5	0.2	-3.7	-2.0	-2.1	-1.9	-2.4	1.9	1.7
Commuting to job workplace: Public transport	1.3	1.5	2.8	0.9	1.0	1.0	1.5	1.7	1.0	-1.7	-0.9
Medication: Atorvastatin	1.3	1.6	4.2	-2.0	-1.5	0.0	-0.8	-0.8	-1.5	1.3	0.9
Basal cell carcinoma (self-reported)	1.3	1.5	3.4	0.9	0.0	1.1	1.6	1.5	1.9	-0.6	1.3
Alcohol drinker status: Previous	1.3	1.5	2.6	-1.6	-1.4	-0.1	-0.9	-1.2	0.1	1.6	1.6
Smoking Status	1.2	2.8	6.0	-2.5	-2.4	-0.5	-1.8	-1.7	-1.3	1.1	1.0
Ever used hormone-replacement therapy (HRT)	1.2	1.5	4.2	1.0	2.0	1.5	1.2	1.7	0.2	-0.6	-0.4
Neuroticism score	1.2	2.5	5.7	0.2	0.6	2.4	1.4	1.4	2.4	-1.8	-1.0
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	6.6	2.5	2.6	0.9	1.2	1.1	1.5	-0.3	-0.1
High blood pressure (siblings)	1.2	1.8	3.3	-0.6	-1.6	-0.8	-1.6	-1.4	-1.1	1.2	1.8
Alcohol intake frequency.	1.2	2.9	5.3	-0.6	-2.0	-0.7	-2.0	-2.0	-1.6	2.3	1.4
Comparative height size at age 10	1.2	6.6	11.7	-0.6	-3.4	-1.2	-2.7	-2.6	-3.4	2.9	2.2
Mother’s age at death	1.2	1.5	4.6	0.9	1.3	-0.3	0.8	0.8	0.9	-1.7	-2.1
Verbal and Numeric Reasoning (VNR)	1.1	2.8	5.9	1.5	1.2	1.4	1.7	1.8	1.1	-1.8	-2.4
Lupus	1.1	1.7	4.8	-1.5	2.2	1.1	0.5	0.1	1.5	-0.6	-1.5
Neuroticism (2016)	1.1	1.6	4.5	1.4	-0.6	2.1	0.9	1.0	0.1	-1.0	-1.9
Supplements: Glucosamine	1.1	1.4	2.3	-0.6	1.3	1.4	1.4	0.8	1.5	-1.4	-0.8
Financial difficulties in last 2 years	1.1	1.5	3.3	0.7	1.1	0.9	1.2	1.0	1.3	-1.5	-1.8
Pulse rate	1.1	1.9	5.9	-2.4	-0.4	-0.6	-1.6	-1.8	-0.5	1.0	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	9.3	0.5	-3.0	-2.0	-1.7	-1.8	-1.9	1.8	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	3.3	-0.3	1.4	1.8	0.6	0.6	1.6	-1.5	-1.4
Medication for pain relief, constipation, heartburn	1.1	1.9	4.3	0.4	-0.3	0.3	1.9	2.1	1.6	-2.0	-0.7
Number of full sisters	1.1	1.3	1.9	-0.7	-1.4	-1.4	-1.2	-0.9	-1.2	1.1	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.0	1.7	0.5	1.6	1.4	1.4	0.7	-0.6	-0.2
Cholesterol lowering medication	1.1	1.6	5.2	-2.3	-0.8	-0.6	-1.3	-1.3	-0.8	1.0	1.3
Reaction Time	1.0	1.8	4.1	2.0	2.0	1.7	1.0	1.2	0.4	-0.4	-1.0
Breast Cancer	1.0	2.3	5.1	1.1	1.9	2.3	1.7	1.5	0.3	-0.5	-1.9
Ovarian Cancer	1.0	1.4	3.2	1.5	1.8	0.4	0.5	0.5	0.7	-1.1	-1.7
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	2.7	-0.1	1.5	1.0	0.3	0.8	1.6	-1.3	-0.1
Father’s age at death	1.0	1.3	4.3	-0.2	0.8	1.0	1.0	1.2	2.1	-1.4	-0.1
Prospective memory result	1.0	1.2	2.9	-1.0	0.4	-0.6	-1.4	-1.7	-0.8	1.1	1.2
Birth weight of first child	1.0	1.8	4.2	-0.5	2.1	0.3	1.3	1.3	1.7	-1.4	-1.3
Blood clot in the leg (DVT)	1.0	1.3	3.0	-0.8	-1.0	0.3	-0.8	-0.9	-1.6	1.7	1.2
Medication: Allopurinol	1.0	1.3	3.4	-0.9	-0.7	-1.9	-1.2	-1.0	-1.4	1.0	0.1
Ever had bowel cancer screening	1.0	1.1	3.3	0.2	1.3	0.4	1.4	1.8	0.8	-0.6	0.9
Osteoarthritis (self-reported)	1.0	1.3	2.6	-1.0	0.0	-1.0	-1.0	-1.5	-1.1	1.6	1.1
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.1	-0.6	-1.8	-1.0	-0.7	-1.0	-1.1	1.2	0.9
Stomach or abdominal pain in last month	0.9	1.1	2.4	0.1	-0.6	-0.5	-1.2	-1.5	-1.6	1.1	1.1
Fluid intelligence score	0.9	1.9	3.9	1.8	0.4	0.6	1.8	1.6	0.7	-1.4	-2.0
Worrier / anxious feelings	0.9	1.7	4.1	1.0	-0.5	2.0	1.4	1.2	1.4	-1.5	-0.9
Commuting to job workplace: Car/motor vehicle	0.9	1.1	2.6	-0.2	0.7	-1.2	-1.6	-1.6	-0.6	0.7	0.7
Illnesses of siblings: Diabetes	0.9	1.1	3.2	1.3	0.8	1.8	1.0	1.0	0.8	-0.6	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	1.7	0.2	0.3	-0.4	-1.3	-0.8	-1.3	1.3	1.3
Breast cancer (self-reported)	0.9	1.1	2.7	-1.3	0.2	-0.8	-1.0	-1.2	0.0	1.2	1.6
Illnesses of father: None of the above (group 1)	0.9	1.1	2.9	-1.4	0.7	-0.9	1.0	0.6	1.7	-1.0	0.0
Wears glasses or contact lenses	0.9	1.0	1.6	1.0	0.9	1.1	1.3	1.2	1.1	-0.8	-0.4
Ever smoked	0.9	1.5	3.3	-1.6	-1.8	-0.8	-1.1	-1.2	-0.8	0.8	1.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.4	-0.7	-1.1	0.2	-0.7	-0.7	-1.5	1.6	1.3
Bipolar Disorder or Schizophrenia	0.8	1.8	4.2	-2.0	0.2	-1.8	-1.1	-1.2	-0.7	1.3	1.6
Depressed Affect (Nagel 2018)	0.8	1.7	5.9	0.7	0.4	2.4	1.0	0.7	1.7	-1.3	-1.1
Intelligence (Savage-Jansen 2018)	0.8	2.3	5.5	2.4	0.3	0.9	1.4	1.1	0.9	-1.9	-2.1
BMI	0.8	4.7	7.7	-2.4	-0.5	-2.1	-2.7	-2.8	-1.2	1.9	2.6
Height	0.8	15.4	40.4	-0.7	-6.4	-2.1	-4.6	-3.7	-4.8	3.8	2.4
Allergy or Eczema	0.8	2.1	6.1	1.0	0.1	2.5	1.7	1.9	0.8	-1.1	-1.0
Hand grip strength (left)	0.8	2.1	4.1	-1.5	-0.9	-0.7	-2.0	-1.9	-1.6	1.5	0.6
Medication: Atenolol	0.8	1.0	2.4	0.6	1.4	1.1	-0.7	-1.0	-0.4	0.2	-1.6
Nervous feelings	0.8	1.5	3.8	-0.2	-0.3	1.5	1.4	1.3	1.9	-1.1	-0.8
Had other major operations	0.8	0.9	3.0	0.0	0.8	-0.9	-1.3	-0.5	-1.7	0.9	0.7
Qualifications: None of the above	0.8	1.8	5.6	1.0	0.9	0.4	1.4	1.5	1.2	-1.2	-2.4
Illnesses of siblings	0.8	1.2	3.2	-0.4	0.3	0.3	1.4	1.0	1.0	-1.3	-1.8
Loud music exposure frequency	0.8	0.9	3.4	-0.1	0.6	-0.3	0.9	0.9	1.8	-1.3	-0.4
Suffer from ‘nerves’	0.8	1.3	3.3	0.0	-0.4	0.7	1.6	1.5	1.8	-1.2	-0.1
Commuting to job workplace: Walk	0.8	0.9	2.7	-0.1	0.3	1.2	1.4	1.6	0.6	-0.5	-0.2
Medication: Gliclazide	0.8	0.9	1.9	-0.6	0.3	0.5	1.1	1.4	1.2	-1.1	-0.7
Number of self-reported non-cancer illnesses	0.8	1.3	2.5	-1.6	-0.3	-0.3	-1.4	-1.1	-0.8	1.4	1.5
Pack years of smoking	0.8	1.2	2.7	-1.0	-1.4	-0.8	-1.5	-1.6	-0.6	0.6	0.4
Schizophrenia (2018)	0.7	1.4	3.2	-1.6	0.3	-1.8	-0.4	-0.7	-0.8	1.4	1.3
Alzheimer’s Disease (in mother)	0.7	0.8	1.4	0.7	-0.5	-0.5	-1.2	-1.2	-1.1	0.8	1.1
Alzheimer’s Disease (in father)	0.7	0.8	2.5	0.0	0.4	-1.4	-0.7	-0.2	-1.6	0.9	0.6
Trunk fat percentage	0.7	2.7	4.9	0.3	1.6	1.0	1.8	1.9	2.2	-2.2	-1.3
Serious illness, injury or assault to yourself	0.7	0.8	2.4	-0.4	-0.2	0.2	-1.1	-1.0	-0.8	1.5	1.2
Noisy workplace	0.7	0.9	2.2	1.2	1.5	1.2	-0.1	0.4	0.5	-0.1	-1.3
Leg fat percentage (right)	0.7	2.5	6.0	0.2	1.5	1.4	1.8	1.7	2.5	-1.8	-0.6
Supplements: Vitamin C	0.7	0.8	2.7	0.2	0.4	-0.0	1.4	1.6	0.8	-0.6	-0.9
Average weekly red wine intake	0.7	1.0	1.6	-0.3	1.2	0.6	1.2	1.2	0.7	-1.3	-1.1
Diabetes diagnosed by doctor	0.7	1.2	2.8	-1.0	1.7	1.2	0.4	0.8	1.3	-1.2	-0.6
Medication for cholesterol	0.7	1.1	2.5	0.6	0.2	0.4	1.5	1.2	0.8	-1.1	-1.6
Diastolic blood pressure, automated reading	0.7	2.2	6.3	-0.9	-0.8	-2.5	-1.6	-1.8	-0.7	1.1	1.4
Fasting Glucose	0.6	0.7	2.1	0.5	-0.6	-0.7	-0.4	-0.6	-1.4	1.2	0.7
HDL Cholesterol	0.6	1.1	2.8	0.0	0.7	1.7	1.5	1.6	0.4	0.0	0.0
Schizophrenia (2014)	0.6	1.4	3.6	-1.1	0.4	-1.4	-0.6	-0.7	-0.9	1.9	1.6
Triglycerides	0.6	1.0	2.9	0.0	-1.0	-1.1	-1.7	-1.4	-1.1	0.0	0.0
Hair Pigment	0.6	16.4	21.3	-3.4	-3.8	-4.6	-4.3	-4.6	-4.1	4.0	3.3
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.5	0.1	0.6	-0.5	-1.0	-0.7	-0.9	1.1	1.2
Chronic bronchitis/emphysema (father)	0.6	0.7	1.7	-0.2	0.4	0.9	0.9	0.7	1.3	-1.0	-0.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.5	0.3	0.5	0.9	0.9	1.2	0.6	-0.5	-1.2
Hip circumference	0.6	2.6	4.3	-2.0	-0.8	-0.9	-2.1	-1.9	-1.1	1.5	1.9
Tense / ‘highly strung’	0.6	1.0	3.3	0.2	0.5	0.6	0.8	1.1	1.8	-1.4	-0.4
Body fat percentage	0.6	2.5	5.2	0.2	1.7	1.1	1.7	1.7	2.3	-2.0	-1.0
Number of children fathered	0.6	0.7	3.3	0.0	1.8	0.6	-0.5	-0.2	0.0	-0.3	-1.2
Long-standing illness, disability or infirmity	0.6	1.0	2.6	0.4	1.1	1.4	0.9	0.4	1.6	-0.9	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	5.5	0.8	2.3	-0.0	0.5	0.4	-0.1	0.1	-1.0
Mineral and other dietary supplements	0.6	0.8	2.3	0.2	-1.5	-0.9	-1.2	-0.9	-0.8	0.6	0.2
Average weekly champagne plus white wine intake	0.6	0.8	3.1	0.3	-0.5	0.4	1.3	1.8	0.4	-0.9	-0.1
Age started oral contraceptive pill	0.6	0.8	2.0	-0.2	0.1	-0.1	-1.0	-0.7	-1.3	1.2	1.4
Supplements: Calcium	0.6	0.7	2.5	-0.1	0.9	-0.4	0.3	0.3	-0.5	1.2	1.6
LDL Cholesterol	0.5	0.8	1.6	0.0	-1.1	-1.2	-1.3	-1.3	-0.6	0.0	0.0
Systolic Blood Pressure	0.5	2.5	5.6	-1.0	-1.1	-2.0	-2.2	-2.4	-1.0	1.0	1.1
Type 2 Diabetes (T2D) (2018)	0.5	1.0	2.2	-1.3	1.0	0.6	0.0	-0.0	1.5	-1.4	-1.0
Average weekly spirits intake	0.5	0.6	1.4	0.1	1.2	0.8	0.3	0.8	0.9	-1.0	-0.4
Vitamin and mineral supplements	0.5	0.6	1.6	0.7	-0.3	-0.1	-1.3	-1.3	-0.3	-0.6	-1.0
Body mass index (BMI)	0.5	2.2	4.2	-2.0	0.3	-1.2	-1.8	-2.1	-0.5	1.3	1.7
Waist circumference	0.5	1.7	2.6	-1.6	-1.0	-0.9	-1.6	-1.6	-0.9	0.9	1.5
Number of incorrect matches in round	0.5	0.8	2.9	-0.7	1.7	0.8	0.8	1.2	0.2	-0.2	0.2
Alcohol usually taken with meals	0.5	0.7	1.4	-0.6	0.6	0.3	1.0	1.2	1.2	-1.2	0.0
Hair/balding pattern: Pattern 2	0.5	0.6	2.2	1.5	-0.1	-0.7	0.7	0.7	0.6	-0.5	-0.5
Heart attack	0.5	0.6	3.2	-0.6	-0.1	1.8	-0.3	0.3	0.2	-0.7	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	4.1	-0.5	0.1	2.0	-1.1	-0.7	-0.5	0.5	0.1
Falls in the last year	0.5	0.7	3.7	-0.3	-0.0	1.0	0.1	0.5	-0.1	0.9	1.9
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.7	0.1	0.2	0.8	0.5	0.6	0.4	-1.3	-1.3
Medication: Cholesterol lowering	0.5	0.8	1.4	0.9	0.7	1.2	1.1	1.0	0.8	-0.9	-0.3
Hair/balding pattern: Pattern 4	0.5	1.3	2.6	0.5	-0.7	1.6	1.6	1.6	1.1	-1.0	-0.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.0	0.7	0.5	0.4	0.7	0.7	0.9	-1.0	-0.9
Exposure to tobacco smoke outside home	0.5	0.7	1.9	-0.6	-0.8	0.5	0.6	0.7	0.9	-1.4	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.6	-1.0	0.7	1.3	-0.5	-0.4	0.9	-0.7	-0.6
Wheeze or whistling in the chest in last year	0.5	0.9	2.0	-0.6	-1.4	0.7	-1.1	-0.8	-1.4	0.7	-0.2
Emphysema/chronic bronchitis	0.5	0.6	1.6	0.8	-1.1	1.2	0.2	0.6	-0.5	0.5	0.7
Illnesses of father: Heart disease	0.5	0.8	4.6	0.3	-0.1	2.1	0.0	0.1	-0.9	0.2	-0.8
Osteoporosis (self-reported)	0.5	0.6	1.9	-0.4	1.4	-0.5	0.7	1.1	0.4	-0.6	0.3
Arm fat mass (left)	0.5	2.2	4.0	-2.0	-0.5	-1.4	-1.8	-1.9	-0.7	1.2	1.7
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.2	-0.3	-0.4	0.5	-0.9	-1.1	-0.8	0.9	0.9
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.9	0.2	0.4	1.1	1.1	0.7	0.5	-0.3	-1.4
Alcohol drinker status: Never	0.5	0.5	1.2	0.6	-1.1	0.6	-0.6	-0.6	-1.0	0.7	-0.3
Leg fat percentage (left)	0.5	1.8	4.5	-0.2	1.5	1.0	1.4	1.2	2.1	-1.7	-0.6
Number of operations (self-reported)	0.5	0.7	1.8	-1.0	0.8	0.4	-0.6	-0.1	-1.3	1.0	0.8
Irritability	0.5	0.8	4.1	-0.5	0.2	0.6	0.1	0.2	2.0	-1.2	-0.3
Bipolar Disorder (2018)	0.4	0.7	1.6	-1.3	-0.1	-0.6	-1.2	-1.1	-0.0	0.3	0.9
Alzheimer’s Disease (including proxy)	0.4	0.6	1.8	0.3	-0.2	-1.2	-0.7	-0.5	-1.3	0.3	0.6
Body Mass Index (BMI) (2010)	0.4	0.6	1.7	0.0	0.9	-0.3	-0.9	-1.3	0.6	0.0	0.8
Ulcerative Colitis	0.4	0.6	2.1	-0.6	-0.7	-0.2	0.7	1.4	0.8	-0.9	0.3
Blood Red Count	0.4	4.1	24.0	-0.9	-4.9	2.4	-0.1	0.4	-1.0	-0.2	0.9
Blood White Count	0.4	2.9	7.9	-1.2	-2.0	-0.6	-1.6	-2.2	-1.0	1.2	2.8
Heel T-Score	0.4	3.5	5.0	2.1	2.1	1.3	1.7	1.0	2.2	-1.9	-2.2
Cardiovascular Disease	0.4	1.2	4.1	-0.8	-2.0	0.7	-0.8	-0.8	-1.0	0.8	1.2
Diabetes (father)	0.4	0.5	1.5	-0.0	-0.9	0.1	0.8	0.7	1.2	-0.8	0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.3	-0.2	1.5	0.8	-0.0	0.5	-0.2	0.2	0.2
Multivitamins +/- minerals	0.4	0.5	1.2	-0.6	0.4	-0.1	0.8	0.7	0.0	0.9	1.1
Past tobacco smoking	0.4	0.7	3.6	0.2	1.9	-0.4	0.5	0.5	0.7	-0.5	-0.6
Allergy	0.4	1.0	4.8	0.3	0.7	-2.2	-0.7	-1.1	-0.1	0.4	0.7
Medication: Simvastatin	0.4	0.6	1.5	0.3	0.9	0.5	0.9	0.8	1.2	-0.7	0.5
Medication: Paracetamol	0.4	0.7	3.9	0.8	2.0	0.8	-0.1	-0.3	-0.4	0.5	-0.6
Medication: Amlodipine	0.4	0.5	1.8	-0.7	1.3	-0.6	-0.4	-0.4	1.0	-0.4	0.4
Birth weight	0.4	0.9	2.2	0.5	0.0	-1.5	-1.0	-1.3	-0.7	1.0	0.6
Shortness of breath walking on level ground	0.4	0.5	1.6	0.5	0.8	1.2	0.1	-0.0	0.3	-0.1	-1.2
Eye problems/disorders: None of the above	0.4	0.5	1.2	-0.5	-0.6	-0.9	-0.8	-0.4	-1.1	0.6	0.1
Neck or shoulder pain in last month	0.4	0.6	1.8	-0.0	0.2	-0.1	-1.2	-1.0	-1.4	0.7	0.0
Angina (self-reported)	0.4	0.5	1.8	0.1	0.6	1.1	-0.6	-0.3	-0.5	-0.0	-1.4
Medication: Seretide 50 evohaler	0.4	0.5	2.0	-1.4	-1.0	-0.6	-0.2	-0.2	-0.5	0.3	0.6
Overall health rating	0.4	1.0	4.0	0.2	1.3	0.7	0.4	0.5	2.0	-1.0	0.2
Had major operations	0.4	0.5	1.3	-1.1	0.8	1.1	0.5	0.5	0.2	-0.1	-0.5
Age at last live birth	0.4	0.6	1.8	-0.8	0.9	0.1	0.3	0.3	0.7	-1.4	-1.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.7	-0.2	-0.6	-1.0	-0.5	-0.5	-0.5	0.7	1.3
Mood swings	0.4	0.6	1.5	0.9	0.3	0.3	0.7	0.4	1.1	-1.2	-0.8
Friendships satisfaction	0.4	0.5	1.9	-0.5	-0.5	0.5	-0.4	0.0	-0.4	1.0	1.4
Medication: Blood pressure	0.4	0.7	2.1	-0.6	0.2	0.5	-1.2	-0.9	-0.1	0.5	1.4
Medication: Paracetamol	0.4	0.6	1.7	0.8	1.3	0.7	-0.3	-0.4	-0.8	1.2	0.3
Risk taking	0.4	0.6	2.4	-0.9	1.5	0.4	0.2	0.7	0.1	-0.7	-0.8
Fractured/broken bones in last 5 years	0.4	0.5	2.9	-0.4	1.7	-0.3	-0.2	0.1	-0.8	-0.2	-0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.6	-0.9	-0.4	1.6	-0.6	0.0	-0.3	-0.3	-0.1
Heart disease (siblings)	0.4	0.5	3.1	-0.1	1.8	0.0	-0.1	0.0	-0.5	0.5	-0.1
Depression (Nagel 2018)	0.3	0.5	1.3	-1.2	0.5	0.9	0.6	0.1	0.9	-0.5	-0.4
Schizophrenia vs Biploar Disorder	0.3	0.4	1.1	0.0	0.1	-1.1	-1.0	-0.5	-0.7	0.0	0.0
Prostate Cancer	0.3	0.5	0.9	-0.9	-0.1	0.7	0.9	0.9	0.6	-0.2	0.7
HbA1C	0.3	0.3	1.1	1.1	0.5	0.8	0.2	0.4	0.3	-0.3	-0.5
Rheumatoid Arthritis	0.3	0.5	1.6	-0.2	1.3	0.6	0.3	0.4	0.2	-0.9	-0.7
Chronotype (morning person)	0.3	0.7	2.0	-1.1	1.4	-0.2	0.1	0.3	1.1	-0.9	-0.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.8	-1.0	0.1	1.3	0.1	-0.1	0.1	-0.3	-0.5
Angina	0.3	0.4	1.4	-0.3	0.5	0.8	-0.8	-0.4	-0.6	0.0	-1.2
Medication for hormone replacement therapy	0.3	0.3	0.7	0.8	0.1	-0.0	-0.5	-0.4	-0.6	0.9	0.5
Severe depression (siblings)	0.3	0.3	1.7	0.5	-0.1	1.3	0.1	0.5	-0.4	-0.2	0.5
Townsend deprivation index at recruitment	0.3	0.5	1.1	0.0	-0.8	1.1	0.9	0.8	0.3	-0.4	-0.4
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.3	-0.0	0.1	1.5	0.8	0.8	0.5	-0.7	-1.0
Time employed in main current job	0.3	0.3	0.6	0.4	0.8	0.6	0.5	0.7	0.4	-0.6	0.5
Number of live births	0.3	0.5	1.8	-0.5	-0.2	-0.6	-0.4	-0.2	-0.7	0.7	1.3
Happiness	0.3	0.3	2.0	0.3	-0.2	1.4	-0.4	-0.3	-0.2	0.4	-0.3
Asthma	0.3	0.5	1.8	-1.4	-0.2	0.9	-0.7	-0.1	-0.8	0.6	-0.2
Lung cancer (father)	0.3	0.4	1.0	-0.6	-1.0	-0.9	-0.2	-0.6	-0.2	0.3	0.5
Illnesses of mother	0.3	0.3	1.0	0.0	-1.0	0.1	0.9	0.7	-0.2	-0.2	-0.4
Arm fat mass (right)	0.3	1.4	2.8	-1.7	-0.1	-1.0	-1.5	-1.6	-0.4	0.9	1.4
Glaucoma (self-reported)	0.3	0.3	0.6	-0.5	-0.7	-0.8	-0.3	-0.0	-0.5	0.6	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.1	-0.0	0.8	0.7	-0.6	0.0	-1.0	0.5	-0.1
Heart disease (mother)	0.3	0.3	1.4	-0.5	1.2	0.9	-0.0	-0.2	-0.1	0.4	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.8	0.1	0.4	1.4	0.5	0.4	0.2	0.1	0.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.8	-0.3	-0.5	0.4	-0.1	0.1	0.3	0.3	1.4
Smoking status: Previous	0.3	0.5	1.6	0.5	-1.2	1.3	0.6	0.6	-0.1	-0.1	0.3
Eye problems/disorders: Cataract	0.3	0.3	0.6	0.7	-0.8	0.4	-0.5	-0.8	-0.1	0.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.2	-0.9	-0.9	-0.9	-0.7	-1.1	0.1	0.2	1.1
Miserableness	0.3	0.6	1.5	-1.2	-1.2	0.3	-0.8	-0.9	-0.2	0.2	0.1
Ever taken oral contraceptive pill	0.3	0.3	0.8	-0.2	-0.2	0.5	0.5	0.8	0.1	-0.7	-0.9
Medication: Bendroflumethiazide	0.3	0.5	1.6	0.2	1.1	0.7	-0.0	0.3	1.2	-0.7	0.0
Medication: Lisinopril	0.3	0.4	1.2	-1.1	-0.2	-0.7	-0.9	-0.4	-0.4	0.1	0.2
Unable to work because of sickness or disability	0.3	0.4	1.2	0.3	-0.1	1.1	0.7	0.8	0.5	0.2	0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.9	0.0	0.9	0.0	0.5	0.9	0.2	-0.6	-0.5
Pain experienced in last month	0.3	0.5	0.9	0.7	-0.7	-0.6	0.9	1.0	0.5	-0.6	-0.1
Ulcerative Colitis (UC)	0.2	0.4	1.3	0.1	-0.9	-1.1	-0.4	0.2	-0.2	0.2	1.1
Crohns Disease (2012)	0.2	0.3	0.6	0.5	-0.5	0.2	0.8	0.4	-0.6	0.3	-0.7
Mean Putamen Volume	0.2	0.2	0.8	-0.9	-0.8	0.3	-0.4	-0.2	0.2	-0.1	-0.3
Primary Biliary Cirrhosis	0.2	0.3	0.9	-0.6	-1.0	-0.7	-0.2	0.6	0.0	0.1	-0.3
Respiratory disease	0.2	0.4	1.1	-1.0	-0.7	1.0	-0.1	0.4	-0.2	0.4	0.3
Number of treatments/medications taken	0.2	0.4	1.1	0.2	0.3	1.1	-0.5	-0.6	-0.1	0.5	0.9
Sensitivity / hurt feelings	0.2	0.3	1.0	0.0	-0.7	1.0	0.7	0.4	0.3	-0.1	0.5
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	-0.5	0.7	0.1	-0.2	0.7	0.1	-0.0	0.8
Taking other prescription medications	0.2	0.3	1.1	-0.4	1.0	0.9	0.1	0.6	0.3	-0.2	0.3
Age when periods started (menarche)	0.2	0.5	1.5	-0.7	-1.2	-0.6	0.1	0.2	0.2	-0.2	-1.1
High blood pressure (mother)	0.2	0.3	1.0	0.3	-0.1	-1.0	-0.9	-0.6	-0.1	0.2	0.5
Hearing difficulty/problems with background noise	0.2	0.3	1.3	0.7	-1.1	0.5	0.0	0.3	-0.3	-0.0	0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.5	-1.2	-0.4	0.4	-0.1	-0.1	0.0	-0.1	0.3
Alcohol intake versus 10 years previously	0.2	0.3	0.6	0.3	-0.8	-0.5	0.7	0.5	0.6	-0.4	0.2
Breastfed as a baby	0.2	0.2	0.8	-0.9	-0.6	0.3	0.1	0.5	0.4	-0.3	0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	-0.4	-0.6	-0.3	-0.5	-0.7	-0.1	0.2	-0.9
Gout (self-reported)	0.2	0.3	1.1	-0.3	1.1	-0.2	0.2	0.3	0.1	-0.3	-1.0
Comparative body size at age 10	0.2	0.6	2.8	0.4	0.0	-0.7	0.6	0.0	1.7	-0.8	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	-1.2	0.3	-0.1	-0.0	-0.3	-0.1	0.2	-0.5
Age at first live birth	0.2	0.4	0.7	-0.2	0.3	-0.8	-0.6	-0.7	0.1	-0.7	-0.9
Health satisfaction	0.2	0.3	1.3	-0.2	0.2	0.6	0.6	0.4	1.1	-0.2	0.0
Qualifications: College or University degree	0.2	0.5	1.4	0.6	-0.5	0.3	0.5	0.4	-0.9	-0.7	-1.2
Medication: Blood pressure	0.2	0.3	1.5	0.3	1.2	-0.6	0.2	0.6	0.1	-0.3	0.3
Medication: Omeprazole	0.2	0.2	0.9	-0.4	0.1	-0.9	-0.2	0.1	-0.4	0.4	0.6
Pulse rate, automated reading	0.2	0.6	3.6	-0.5	1.9	0.1	-0.0	0.0	0.6	-0.4	0.0
Chest pain or discomfort	0.2	0.3	1.3	0.0	0.0	-0.1	-0.8	-0.5	-1.1	0.4	-0.2
Family relationship satisfaction	0.2	0.2	0.8	-0.6	-0.0	0.9	0.3	0.7	0.0	-0.5	-0.2
Medication: Aspirin	0.2	0.3	1.0	-1.0	0.6	0.3	-0.7	-0.8	0.0	0.0	0.1
Knee pain experienced in last month	0.2	0.3	1.1	-1.0	0.8	0.3	-0.1	-0.4	0.4	0.1	-0.2
Arm fat percentage (left)	0.2	0.8	2.3	-0.5	1.4	0.3	0.7	0.6	1.5	-0.8	0.2
Asthma (self-reported)	0.2	0.4	1.5	-1.2	-0.0	0.9	-0.4	0.0	-0.5	0.3	-0.6
Medication: Aspirin	0.2	0.3	1.0	-1.0	0.8	0.5	-0.2	-0.3	0.4	-0.4	-0.3
Hearing aid user	0.2	0.2	1.3	1.2	-0.3	-0.4	0.1	0.2	0.2	-0.3	-0.2
Average weekly beer plus cider intake	0.2	0.4	1.0	-0.6	0.5	0.3	0.5	0.1	0.8	-0.5	-1.0
Myopia	0.2	0.3	0.7	0.2	0.1	-0.0	0.7	0.8	0.6	-0.5	0.6
Leg fat mass (left)	0.2	0.7	1.8	-1.3	0.0	-0.8	-0.9	-1.1	0.1	0.2	1.0
Crohns Disease (2017)	0.1	0.2	1.0	0.2	-1.0	-0.3	0.6	0.3	-0.3	0.2	-0.4
Irritable Bowel Disease (IBD)	0.1	0.3	1.0	0.1	-1.0	-0.7	0.4	0.6	-0.1	0.1	0.3
Blood Eosinophil Count	0.1	1.1	5.7	-2.4	0.0	1.0	0.7	0.5	0.9	-0.9	-0.1
Blood Platelet Count	0.1	1.5	9.1	-0.0	-3.0	-0.3	-0.6	-1.6	-0.3	0.1	0.4
Waist Hip Ratio (WHR)	0.1	0.5	3.1	0.2	-1.8	0.6	-0.0	-0.1	-0.9	0.0	-0.0
Lung FEV1/FVC ratio	0.1	0.6	1.1	-0.8	0.7	-1.0	-0.6	-1.0	1.0	0.5	-0.2
Lung FVC	0.1	0.3	1.7	0.3	-1.3	-0.3	0.1	0.0	0.1	0.1	0.5
Systolic blood pressure, automated reading	0.1	0.4	1.1	0.6	0.5	-1.0	-0.1	-0.4	1.0	-0.0	0.7
Maternal smoking around birth	0.1	0.2	0.4	0.2	-0.3	0.5	-0.6	-0.1	-0.0	-0.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.0	0.4	-0.0	-0.2	0.5	-0.1	0.8	-0.3	-1.0
High blood pressure	0.1	0.3	1.2	-0.5	-0.3	-0.3	-0.9	-0.2	0.3	-0.2	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.0	1.0	-0.3	-0.7	0.3	-0.3	0.5	0.2	0.1
Pain all over the body in last month	0.1	0.1	0.4	-0.3	0.6	0.4	0.2	0.2	0.6	0.2	-0.3
Arm fat percentage (right)	0.1	0.5	1.7	-0.3	1.1	0.4	0.6	0.5	1.3	-0.6	0.0
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	0.1	0.2	-0.2	-0.1	-0.1	-1.0	0.8	-0.2
Whole body fat mass	0.1	0.3	0.9	-0.9	0.1	-0.4	-0.6	-0.6	0.2	0.0	0.6
Leg fat mass (right)	0.1	0.4	1.1	-1.0	0.1	-0.5	-0.7	-0.8	0.4	0.1	1.0
Hypertension (Self-reported)	0.1	0.2	0.9	-0.2	0.3	-0.1	-0.4	0.2	0.7	-0.5	0.9
Loneliness, isolation	0.1	0.2	0.4	-0.3	-0.4	0.5	-0.6	-0.3	-0.5	0.5	0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	0.5	-0.0	-0.5	0.5	0.5	0.2	-0.1	0.0
High cholesterol (Self-reported)	0.1	0.2	0.7	-0.7	-0.4	0.8	0.5	0.3	0.2	-0.1	-0.2
Ever depressed for a whole week	0.1	0.2	0.4	0.3	0.4	-0.2	0.5	0.6	0.4	-0.1	-0.5
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.5	0.4	0.2	-0.1	0.6	0.0	-0.4	0.4	-0.7
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.5	2.5	-0.5	-0.4	0.1	0.6	0.3	-0.0	-0.7	-1.6
Trunk fat mass	0.0	0.1	0.6	-0.8	0.1	-0.2	-0.3	-0.2	0.4	-0.3	0.2

Hub : Genes

AP2A1

Models

Trait associations