Hub : Genes

AP2A1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0670 0.0300 4.6e-03 -0.002 0.018 0.021 0.013 0.007 7.6e-01 2.6e-03 1.1e-03 0.0089 4.1e-02
2 GTEx Brain Cerebellar Hemisphere 0.3250 0.1050 1.3e-03 0.052 NA 0.014 NA 0.062 1.9e-02 NA 1.4e-01 NA 1.1e-02
3 GTEx Brain Cerebellum 0.2290 0.0860 6.5e-03 -0.007 NA -0.010 NA -0.010 6.0e-01 NA 8.5e-01 NA 9.2e-01
4 GTEx Esophagus Mucosa 0.1760 0.0490 4.8e-06 0.092 NA 0.127 NA 0.119 9.6e-07 NA 7.7e-09 NA 2.3e-08
5 GTEx Nerve Tibial 0.1612 0.0529 1.2e-04 0.050 NA 0.052 NA 0.069 1.8e-04 NA 1.4e-04 NA 1.4e-05
6 GTEx Skin Sun Exposed Lower leg 0.1530 0.0420 1.1e-05 0.080 NA 0.070 NA 0.063 3.5e-07 NA 1.9e-06 NA 6.4e-06
7 TCGA Breast Invasive Carcinoma 0.0385 0.0161 7.1e-07 0.035 0.036 0.037 NA 0.039 1.0e-07 7.0e-08 4.4e-08 NA 1.8e-08
8 TCGA Kidney Renal Papillary Cell Carcinoma 0.0880 0.0450 3.0e-03 0.052 0.024 0.039 NA 0.045 5.8e-04 1.5e-02 2.7e-03 NA 1.3e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.4 0.7 1.6 -1.3 -0.1 -0.6 -1.2 -1.1 -0.0 0.3 0.9
Bipolar Disorder or Schizophrenia 0.8 1.8 4.2 -2.0 0.2 -1.8 -1.1 -1.2 -0.7 1.3 1.6
Depressed Affect (Nagel 2018) 0.8 1.7 5.9 0.7 0.4 2.4 1.0 0.7 1.7 -1.3 -1.1
Depression (Nagel 2018) 0.3 0.5 1.3 -1.2 0.5 0.9 0.6 0.1 0.9 -0.5 -0.4
Intelligence (Savage-Jansen 2018) 0.8 2.3 5.5 2.4 0.3 0.9 1.4 1.1 0.9 -1.9 -2.1
Neuroticism (Nagel 2018) 1.8 4.3 9.4 0.4 0.1 3.1 2.4 1.9 2.7 -2.3 -1.5
Schizophrenia (2018) 0.7 1.4 3.2 -1.6 0.3 -1.8 -0.4 -0.7 -0.8 1.4 1.3
Schizophrenia vs Biploar Disorder 0.3 0.4 1.1 0.0 0.1 -1.1 -1.0 -0.5 -0.7 0.0 0.0
Worry (Nagel 2018) 2.2 4.6 8.5 0.5 0.2 2.3 2.9 2.5 2.9 -2.5 -1.5
Alzheimer’s Disease (in mother) 0.7 0.8 1.4 0.7 -0.5 -0.5 -1.2 -1.2 -1.1 0.8 1.1
Alzheimer’s Disease (in father) 0.7 0.8 2.5 0.0 0.4 -1.4 -0.7 -0.2 -1.6 0.9 0.6
Alzheimer’s Disease (including proxy) 0.4 0.6 1.8 0.3 -0.2 -1.2 -0.7 -0.5 -1.3 0.3 0.6
Crohns Disease (2017) 0.1 0.2 1.0 0.2 -1.0 -0.3 0.6 0.3 -0.3 0.2 -0.4
Irritable Bowel Disease (IBD) 0.1 0.3 1.0 0.1 -1.0 -0.7 0.4 0.6 -0.1 0.1 0.3
Ulcerative Colitis (UC) 0.2 0.4 1.3 0.1 -0.9 -1.1 -0.4 0.2 -0.2 0.2 1.1
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 1.0 1.8 4.1 2.0 2.0 1.7 1.0 1.2 0.4 -0.4 -1.0
Verbal and Numeric Reasoning (VNR) 1.1 2.8 5.9 1.5 1.2 1.4 1.7 1.8 1.1 -1.8 -2.4
Breast Cancer 1.0 2.3 5.1 1.1 1.9 2.3 1.7 1.5 0.3 -0.5 -1.9
Ovarian Cancer 1.0 1.4 3.2 1.5 1.8 0.4 0.5 0.5 0.7 -1.1 -1.7
Prostate Cancer 0.3 0.5 0.9 -0.9 -0.1 0.7 0.9 0.9 0.6 -0.2 0.7
Age at First Birth 3.0 4.4 7.6 0.7 1.9 2.5 1.9 1.9 1.8 -2.8 -2.6
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.6 1.7 0.0 0.9 -0.3 -0.9 -1.3 0.6 0.0 0.8
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.2 0.3 0.6 0.5 -0.5 0.2 0.8 0.4 -0.6 0.3 -0.7
Mean Putamen Volume 0.2 0.2 0.8 -0.9 -0.8 0.3 -0.4 -0.2 0.2 -0.1 -0.3
Fasting Glucose 0.6 0.7 2.1 0.5 -0.6 -0.7 -0.4 -0.6 -1.4 1.2 0.7
HbA1C 0.3 0.3 1.1 1.1 0.5 0.8 0.2 0.4 0.3 -0.3 -0.5
HDL Cholesterol 0.6 1.1 2.8 0.0 0.7 1.7 1.5 1.6 0.4 0.0 0.0
LDL Cholesterol 0.5 0.8 1.6 0.0 -1.1 -1.2 -1.3 -1.3 -0.6 0.0 0.0
Lupus 1.1 1.7 4.8 -1.5 2.2 1.1 0.5 0.1 1.5 -0.6 -1.5
Neuroticism (2016) 1.1 1.6 4.5 1.4 -0.6 2.1 0.9 1.0 0.1 -1.0 -1.9
Primary Biliary Cirrhosis 0.2 0.3 0.9 -0.6 -1.0 -0.7 -0.2 0.6 0.0 0.1 -0.3
Rheumatoid Arthritis 0.3 0.5 1.6 -0.2 1.3 0.6 0.3 0.4 0.2 -0.9 -0.7
Schizophrenia (2014) 0.6 1.4 3.6 -1.1 0.4 -1.4 -0.6 -0.7 -0.9 1.9 1.6
Triglycerides 0.6 1.0 2.9 0.0 -1.0 -1.1 -1.7 -1.4 -1.1 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.4 0.6 2.1 -0.6 -0.7 -0.2 0.7 1.4 0.8 -0.9 0.3
Blood Eosinophil Count 0.1 1.1 5.7 -2.4 0.0 1.0 0.7 0.5 0.9 -0.9 -0.1
Blood Platelet Count 0.1 1.5 9.1 -0.0 -3.0 -0.3 -0.6 -1.6 -0.3 0.1 0.4
Blood Red Count 0.4 4.1 24.0 -0.9 -4.9 2.4 -0.1 0.4 -1.0 -0.2 0.9
Blood White Count 0.4 2.9 7.9 -1.2 -2.0 -0.6 -1.6 -2.2 -1.0 1.2 2.8
Heel T-Score 0.4 3.5 5.0 2.1 2.1 1.3 1.7 1.0 2.2 -1.9 -2.2
BMI 0.8 4.7 7.7 -2.4 -0.5 -2.1 -2.7 -2.8 -1.2 1.9 2.6
Height 0.8 15.4 40.4 -0.7 -6.4 -2.1 -4.6 -3.7 -4.8 3.8 2.4
Waist Hip Ratio (WHR) 0.1 0.5 3.1 0.2 -1.8 0.6 -0.0 -0.1 -0.9 0.0 -0.0
Systolic Blood Pressure 0.5 2.5 5.6 -1.0 -1.1 -2.0 -2.2 -2.4 -1.0 1.0 1.1
Smoking Status 1.2 2.8 6.0 -2.5 -2.4 -0.5 -1.8 -1.7 -1.3 1.1 1.0
Allergy or Eczema 0.8 2.1 6.1 1.0 0.1 2.5 1.7 1.9 0.8 -1.1 -1.0
Cardiovascular Disease 0.4 1.2 4.1 -0.8 -2.0 0.7 -0.8 -0.8 -1.0 0.8 1.2
Hypothyroidism (self reported) 1.3 3.0 8.1 2.9 2.6 1.1 1.6 1.5 1.8 -0.3 0.0
Respiratory disease 0.2 0.4 1.1 -1.0 -0.7 1.0 -0.1 0.4 -0.2 0.4 0.3
Type 2 Diabetes (T2D) (2018) 0.5 1.0 2.2 -1.3 1.0 0.6 0.0 -0.0 1.5 -1.4 -1.0
Lung FEV1/FVC ratio 0.1 0.6 1.1 -0.8 0.7 -1.0 -0.6 -1.0 1.0 0.5 -0.2
Lung FVC 0.1 0.3 1.7 0.3 -1.3 -0.3 0.1 0.0 0.1 0.1 0.5
Neuroticism 4.3 10.3 17.4 1.2 2.0 4.2 3.3 3.1 4.0 -3.8 -2.9
Chronotype (morning person) 0.3 0.7 2.0 -1.1 1.4 -0.2 0.1 0.3 1.1 -0.9 -0.7
Hair Pigment 0.6 16.4 21.3 -3.4 -3.8 -4.6 -4.3 -4.6 -4.1 4.0 3.3
Tanning 0.0 0.5 2.5 -0.5 -0.4 0.1 0.6 0.3 -0.0 -0.7 -1.6
Hand grip strength (left) 0.8 2.1 4.1 -1.5 -0.9 -0.7 -2.0 -1.9 -1.6 1.5 0.6
Number of treatments/medications taken 0.2 0.4 1.1 0.2 0.3 1.1 -0.5 -0.6 -0.1 0.5 0.9
Average weekly spirits intake 0.5 0.6 1.4 0.1 1.2 0.8 0.3 0.8 0.9 -1.0 -0.4
Sensitivity / hurt feelings 0.2 0.3 1.0 0.0 -0.7 1.0 0.7 0.4 0.3 -0.1 0.5
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.8 -1.0 0.1 1.3 0.1 -0.1 0.1 -0.3 -0.5
Hearing difficulty/problems: Yes 1.5 2.3 5.4 -0.2 -1.6 -1.0 -1.7 -1.4 -2.3 1.6 1.4
Relative age of first facial hair 1.3 2.8 5.2 0.2 0.9 -0.2 2.3 2.1 1.8 -2.3 -1.9
Other serious medical condition/disability diagnosed by doctor 1.8 2.3 6.9 -0.4 -1.1 -0.3 -1.0 -0.9 -2.2 2.6 1.9
Ever used hormone-replacement therapy (HRT) 1.2 1.5 4.2 1.0 2.0 1.5 1.2 1.7 0.2 -0.6 -0.4
Ever had hysterectomy (womb removed) 0.2 0.2 0.7 -0.5 0.7 0.1 -0.2 0.7 0.1 -0.0 0.8
Systolic blood pressure, automated reading 0.1 0.4 1.1 0.6 0.5 -1.0 -0.1 -0.4 1.0 -0.0 0.7
Eye problems/disorders: Diabetes related eye disease 3.8 4.1 6.3 -0.1 2.3 1.7 2.5 1.8 2.5 -2.1 -2.1
Angina 0.3 0.4 1.4 -0.3 0.5 0.8 -0.8 -0.4 -0.6 0.0 -1.2
Medication for hormone replacement therapy 0.3 0.3 0.7 0.8 0.1 -0.0 -0.5 -0.4 -0.6 0.9 0.5
Vitamin and mineral supplements 0.5 0.6 1.6 0.7 -0.3 -0.1 -1.3 -1.3 -0.3 -0.6 -1.0
Supplements: Zinc 1.8 2.0 5.0 0.6 2.2 1.1 1.5 1.5 1.5 -1.1 -1.1
Medication: Co-codamol 1.9 2.2 8.0 0.5 2.8 1.8 1.3 0.8 1.8 -0.8 -0.1
Medication: Metformin 1.9 2.7 5.6 -0.8 1.7 1.4 1.3 1.7 2.2 -2.4 -1.1
Diabetes (father) 0.4 0.5 1.5 -0.0 -0.9 0.1 0.8 0.7 1.2 -0.8 0.4
Diabetes (mother) 1.4 1.7 4.5 -0.9 -2.1 -1.1 -1.2 -1.3 -1.0 0.9 1.6
Severe depression (siblings) 0.3 0.3 1.7 0.5 -0.1 1.3 0.1 0.5 -0.4 -0.2 0.5
Pack years adult smoking proportion 1.4 2.1 4.0 -1.4 -1.9 -1.2 -1.9 -2.0 -0.9 0.9 0.8
Impedance of leg (right) 4.3 21.0 39.3 3.9 1.5 3.9 6.0 6.3 4.4 -4.9 -4.1
Leg fat-free mass (left) 3.1 16.6 26.8 -3.1 -3.5 -3.2 -5.2 -5.1 -4.3 4.1 3.7
Trunk fat percentage 0.7 2.7 4.9 0.3 1.6 1.0 1.8 1.9 2.2 -2.2 -1.3
Hand grip strength (right) 1.3 3.6 6.5 -1.1 -1.4 -1.8 -2.5 -2.4 -2.4 2.0 1.0
Townsend deprivation index at recruitment 0.3 0.5 1.1 0.0 -0.8 1.1 0.9 0.8 0.3 -0.4 -0.4
Current tobacco smoking 3.3 5.3 8.0 -2.2 -2.0 -2.4 -2.8 -2.8 -2.2 2.3 1.5
Average weekly fortified wine intake 2.7 3.2 3.9 -1.9 -1.9 -0.6 -2.0 -1.9 -1.8 2.0 1.7
Maternal smoking around birth 0.1 0.2 0.4 0.2 -0.3 0.5 -0.6 -0.1 -0.0 -0.3 -0.6
Fed-up feelings 2.3 4.1 10.8 2.0 1.3 3.3 1.6 1.6 1.9 -1.5 -2.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.2 4.6 1.0 1.2 2.1 1.4 1.5 1.9 -1.4 -1.0
Relative age voice broke 4.7 7.2 12.4 1.9 2.2 2.0 3.5 2.9 3.1 -2.8 -2.6
Taking other prescription medications 0.2 0.3 1.1 -0.4 1.0 0.9 0.1 0.6 0.3 -0.2 0.3
Age when periods started (menarche) 0.2 0.5 1.5 -0.7 -1.2 -0.6 0.1 0.2 0.2 -0.2 -1.1
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 2.3 -0.2 1.5 0.8 -0.0 0.5 -0.2 0.2 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.0 0.4 -0.0 -0.2 0.5 -0.1 0.8 -0.3 -1.0
Tinnitus: Yes, but not now, but have in the past 1.0 1.0 2.7 -0.1 1.5 1.0 0.3 0.8 1.6 -1.3 -0.1
Qualifications: CSEs or equivalent 2.7 3.6 6.5 -1.7 -2.2 -1.7 -2.0 -2.5 -1.4 1.6 1.9
Serious illness, injury or assault to yourself 0.7 0.8 2.4 -0.4 -0.2 0.2 -1.1 -1.0 -0.8 1.5 1.2
High blood pressure 0.1 0.3 1.2 -0.5 -0.3 -0.3 -0.9 -0.2 0.3 -0.2 1.1
Hayfever, allergic rhinitis or eczema 0.3 0.7 2.3 -0.0 0.1 1.5 0.8 0.8 0.5 -0.7 -1.0
Multivitamins +/- minerals 0.4 0.5 1.2 -0.6 0.4 -0.1 0.8 0.7 0.0 0.9 1.1
Stomach or abdominal pain in last month 0.9 1.1 2.4 0.1 -0.6 -0.5 -1.2 -1.5 -1.6 1.1 1.1
Supplements: Glucosamine 1.1 1.4 2.3 -0.6 1.3 1.4 1.4 0.8 1.5 -1.4 -0.8
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 1.5 0.1 0.6 -0.5 -1.0 -0.7 -0.9 1.1 1.2
Medication: Atenolol 0.8 1.0 2.4 0.6 1.4 1.1 -0.7 -1.0 -0.4 0.2 -1.6
Medication: Levothyroxine sodium 1.5 2.5 6.2 2.5 2.2 1.6 1.6 1.2 1.7 -0.2 0.3
Sitting height 2.7 19.0 29.2 -2.7 -5.4 -2.8 -5.2 -5.0 -5.3 4.4 2.9
Chronic bronchitis/emphysema (father) 0.6 0.7 1.7 -0.2 0.4 0.9 0.9 0.7 1.3 -1.0 -0.5
High blood pressure (mother) 0.2 0.3 1.0 0.3 -0.1 -1.0 -0.9 -0.6 -0.1 0.2 0.5
Body mass index (BMI) 0.5 2.2 4.2 -2.0 0.3 -1.2 -1.8 -2.1 -0.5 1.3 1.7
Impedance of leg (left) 3.6 17.7 32.0 3.5 1.6 3.2 5.6 5.7 3.9 -4.7 -4.1
Leg predicted mass (left) 3.2 16.7 26.6 -3.0 -3.5 -3.3 -5.2 -5.0 -4.3 4.2 3.8
Trunk fat mass 0.0 0.1 0.6 -0.8 0.1 -0.2 -0.3 -0.2 0.4 -0.3 0.2
Waist circumference 0.5 1.7 2.6 -1.6 -1.0 -0.9 -1.6 -1.6 -0.9 0.9 1.5
Number of incorrect matches in round 0.5 0.8 2.9 -0.7 1.7 0.8 0.8 1.2 0.2 -0.2 0.2
Past tobacco smoking 0.4 0.7 3.6 0.2 1.9 -0.4 0.5 0.5 0.7 -0.5 -0.6
Alcohol usually taken with meals 0.5 0.7 1.4 -0.6 0.6 0.3 1.0 1.2 1.2 -1.2 0.0
Nervous feelings 0.8 1.5 3.8 -0.2 -0.3 1.5 1.4 1.3 1.9 -1.1 -0.8
Frequency of tenseness / restlessness in last 2 weeks 2.2 3.5 6.9 0.5 0.2 2.6 2.4 2.2 1.9 -1.9 -1.7
Hearing difficulty/problems with background noise 0.2 0.3 1.3 0.7 -1.1 0.5 0.0 0.3 -0.3 -0.0 0.2
Hair/balding pattern: Pattern 2 0.5 0.6 2.2 1.5 -0.1 -0.7 0.7 0.7 0.6 -0.5 -0.5
Had menopause 2.3 2.8 6.1 0.6 2.2 1.5 1.8 2.5 1.5 -1.7 -0.8
Had other major operations 0.8 0.9 3.0 0.0 0.8 -0.9 -1.3 -0.5 -1.7 0.9 0.7
Forced vital capacity (FVC) 1.8 7.0 19.5 -0.1 -4.4 -2.2 -2.7 -2.5 -3.1 2.3 1.7
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 1.0 1.0 -0.3 -0.7 0.3 -0.3 0.5 0.2 0.1
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 1.5 0.3 0.5 0.9 0.9 1.2 0.6 -0.5 -1.2
Qualifications: None of the above 0.8 1.8 5.6 1.0 0.9 0.4 1.4 1.5 1.2 -1.2 -2.4
Financial difficulties in last 2 years 1.1 1.5 3.3 0.7 1.1 0.9 1.2 1.0 1.3 -1.5 -1.8
Mouth/teeth dental problems 4.7 7.2 10.7 -1.7 -2.7 -2.6 -3.0 -2.6 -3.3 2.5 2.8
Heart attack 0.5 0.6 3.2 -0.6 -0.1 1.8 -0.3 0.3 0.2 -0.7 -0.6
Allergy 0.4 1.0 4.8 0.3 0.7 -2.2 -0.7 -1.1 -0.1 0.4 0.7
Pain all over the body in last month 0.1 0.1 0.4 -0.3 0.6 0.4 0.2 0.2 0.6 0.2 -0.3
Diabetes (self-reported) 1.5 2.3 3.8 -0.7 1.9 1.7 0.9 1.2 1.7 -2.0 -1.4
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 1.5 -1.2 -0.4 0.4 -0.1 -0.1 0.0 -0.1 0.3
Medication: Ramipril 1.9 2.5 4.9 0.9 0.8 2.0 2.2 1.7 2.1 -1.5 0.3
Medication: Simvastatin 0.4 0.6 1.5 0.3 0.9 0.5 0.9 0.8 1.2 -0.7 0.5
Fluid intelligence score 0.9 1.9 3.9 1.8 0.4 0.6 1.8 1.6 0.7 -1.4 -2.0
Illnesses of siblings 0.8 1.2 3.2 -0.4 0.3 0.3 1.4 1.0 1.0 -1.3 -1.8
Neuroticism score 1.2 2.5 5.7 0.2 0.6 2.4 1.4 1.4 2.4 -1.8 -1.0
Weight 1.3 6.3 10.4 -2.2 -1.8 -1.9 -3.2 -3.1 -2.3 2.5 2.5
Impedance of arm (right) 4.6 21.4 42.5 4.1 1.7 3.7 6.2 6.5 4.6 -4.8 -3.7
Arm fat percentage (right) 0.1 0.5 1.7 -0.3 1.1 0.4 0.6 0.5 1.3 -0.6 0.0
Trunk fat-free mass 5.4 31.2 48.6 -3.7 -5.0 -4.2 -7.0 -6.9 -6.2 6.0 4.6
Hip circumference 0.6 2.6 4.3 -2.0 -0.8 -0.9 -2.1 -1.9 -1.1 1.5 1.9
Time employed in main current job 0.3 0.3 0.6 0.4 0.8 0.6 0.5 0.7 0.4 -0.6 0.5
Alcohol intake versus 10 years previously 0.2 0.3 0.6 0.3 -0.8 -0.5 0.7 0.5 0.6 -0.4 0.2
Father’s age at death 1.0 1.3 4.3 -0.2 0.8 1.0 1.0 1.2 2.1 -1.4 -0.1
Worrier / anxious feelings 0.9 1.7 4.1 1.0 -0.5 2.0 1.4 1.2 1.4 -1.5 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 4.1 -0.5 0.1 2.0 -1.1 -0.7 -0.5 0.5 0.1
Falls in the last year 0.5 0.7 3.7 -0.3 -0.0 1.0 0.1 0.5 -0.1 0.9 1.9
Hair/balding pattern: Pattern 3 0.1 0.2 0.9 0.1 0.2 -0.2 -0.1 -0.1 -1.0 0.8 -0.2
Number of live births 0.3 0.5 1.8 -0.5 -0.2 -0.6 -0.4 -0.2 -0.7 0.7 1.3
Forced expiratory volume in 1-second (FEV1) 1.5 5.2 12.4 0.3 -3.5 -2.2 -2.3 -2.3 -2.6 2.1 1.3
Pulse rate 1.1 1.9 5.9 -2.4 -0.4 -0.6 -1.6 -1.8 -0.5 1.0 1.3
Happiness 0.3 0.3 2.0 0.3 -0.2 1.4 -0.4 -0.3 -0.2 0.4 -0.3
Noisy workplace 0.7 0.9 2.2 1.2 1.5 1.2 -0.1 0.4 0.5 -0.1 -1.3
Qualifications: A levels/AS levels or equivalent 1.8 3.9 6.3 -0.7 -2.3 -1.6 -2.5 -2.5 -2.5 1.6 1.4
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 1.7 0.1 0.2 0.8 0.5 0.6 0.4 -1.3 -1.3
Mouth/teeth dental problems: Dentures 3.7 6.2 13.0 1.2 1.7 2.6 2.7 2.4 3.6 -2.8 -2.2
Asthma 0.3 0.5 1.8 -1.4 -0.2 0.9 -0.7 -0.1 -0.8 0.6 -0.2
Medication: Ibuprofen (e.g. Nurofen) 1.5 1.9 5.1 0.9 -1.1 0.2 -1.5 -2.1 -1.4 2.2 0.2
Medication: Cholesterol lowering 0.5 0.8 1.4 0.9 0.7 1.2 1.1 1.0 0.8 -0.9 -0.3
Depression (self-reported) 3.2 3.8 7.9 1.0 2.1 1.3 2.0 1.7 2.8 -2.2 -1.8
Medication: Lansoprazole 4.4 5.0 8.0 1.7 2.7 2.1 2.6 2.8 2.2 -2.2 -1.0
Prospective memory result 1.0 1.2 2.9 -1.0 0.4 -0.6 -1.4 -1.7 -0.8 1.1 1.2
Lung cancer (father) 0.3 0.4 1.0 -0.6 -1.0 -0.9 -0.2 -0.6 -0.2 0.3 0.5
Illnesses of mother 0.3 0.3 1.0 0.0 -1.0 0.1 0.9 0.7 -0.2 -0.2 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.6 9.3 0.5 -3.0 -2.0 -1.7 -1.8 -1.9 1.8 1.5
Pulse wave Arterial Stiffness index 2.7 3.1 5.5 -1.4 -1.4 -1.1 -2.1 -1.8 -1.5 2.1 2.4
Impedance of arm (left) 4.6 21.1 42.1 4.2 2.1 3.2 6.1 6.5 4.6 -4.9 -3.6
Arm fat mass (right) 0.3 1.4 2.8 -1.7 -0.1 -1.0 -1.5 -1.6 -0.4 0.9 1.4
Trunk predicted mass 5.5 31.2 49.0 -3.8 -5.0 -4.2 -7.0 -7.0 -6.2 6.0 4.5
Standing height 1.3 13.1 28.1 -1.2 -5.3 -2.5 -4.1 -3.4 -4.7 3.5 2.5
Length of working week for main job 1.7 1.8 3.5 -0.5 1.8 1.9 0.8 1.6 1.1 -1.2 -1.2
Exposure to tobacco smoke at home 2.7 3.0 5.1 -0.5 1.1 1.2 1.9 2.0 2.1 -1.9 -2.2
Breastfed as a baby 0.2 0.2 0.8 -0.9 -0.6 0.3 0.1 0.5 0.4 -0.3 0.4
Tense / ‘highly strung’ 0.6 1.0 3.3 0.2 0.5 0.6 0.8 1.1 1.8 -1.4 -0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.6 3.3 -0.3 1.4 1.8 0.6 0.6 1.6 -1.5 -1.4
Hair/balding pattern: Pattern 4 0.5 1.3 2.6 0.5 -0.7 1.6 1.6 1.6 1.1 -1.0 -0.1
Birth weight of first child 1.0 1.8 4.2 -0.5 2.1 0.3 1.3 1.3 1.7 -1.4 -1.3
Peak expiratory flow (PEF) 2.5 5.9 10.7 0.0 -3.0 -1.6 -3.1 -2.8 -3.3 2.5 1.1
Pulse wave reflection index 2.8 3.5 5.2 -1.4 -1.9 -1.5 -2.1 -1.8 -2.0 2.3 1.6
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.0 0.7 0.5 0.4 0.7 0.7 0.9 -1.0 -0.9
Loud music exposure frequency 0.8 0.9 3.4 -0.1 0.6 -0.3 0.9 0.9 1.8 -1.3 -0.4
Qualifications: O levels/GCSEs or equivalent 2.4 3.8 8.0 -1.1 -1.6 -1.6 -2.4 -2.6 -1.3 1.6 2.8
Mouth/teeth dental problems: Bleeding gums 1.9 2.4 4.7 1.4 1.0 1.5 1.7 1.5 1.5 -1.4 -2.2
Blood clot in the leg (DVT) 1.0 1.3 3.0 -0.8 -1.0 0.3 -0.8 -0.9 -1.6 1.7 1.2
Medication: Paracetamol 0.4 0.7 3.9 0.8 2.0 0.8 -0.1 -0.3 -0.4 0.5 -0.6
Headache pain in last month 1.9 3.3 7.3 -1.1 -1.1 0.5 -2.6 -2.7 -2.1 2.2 1.0
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 0.8 -0.4 -0.6 -0.3 -0.5 -0.7 -0.1 0.2 -0.9
Glaucoma (self-reported) 0.3 0.3 0.6 -0.5 -0.7 -0.8 -0.3 -0.0 -0.5 0.6 0.6
Gout (self-reported) 0.2 0.3 1.1 -0.3 1.1 -0.2 0.2 0.3 0.1 -0.3 -1.0
Hypothyroidism/myxoedema (self-reported) 1.2 2.3 6.6 2.5 2.6 0.9 1.2 1.1 1.5 -0.3 -0.1
Medication: Amlodipine 0.4 0.5 1.8 -0.7 1.3 -0.6 -0.4 -0.4 1.0 -0.4 0.4
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.1 -0.0 0.8 0.7 -0.6 0.0 -1.0 0.5 -0.1
Birth weight 0.4 0.9 2.2 0.5 0.0 -1.5 -1.0 -1.3 -0.7 1.0 0.6
Chronic bronchitis/emphysema (mother) 2.4 2.8 6.5 -0.5 1.5 1.5 1.6 1.4 2.5 -2.0 -1.7
High blood pressure (siblings) 1.2 1.8 3.3 -0.6 -1.6 -0.8 -1.6 -1.4 -1.1 1.2 1.8
Forced vital capacity (FVC), Best measure 1.3 4.7 13.5 0.2 -3.7 -2.0 -2.1 -1.9 -2.4 1.9 1.7
Body fat percentage 0.6 2.5 5.2 0.2 1.7 1.1 1.7 1.7 2.3 -2.0 -1.0
Leg fat percentage (right) 0.7 2.5 6.0 0.2 1.5 1.4 1.8 1.7 2.5 -1.8 -0.6
Arm fat-free mass (right) 4.3 22.0 36.2 -3.8 -3.7 -3.7 -5.9 -6.0 -5.1 4.7 3.9
Exposure to tobacco smoke outside home 0.5 0.7 1.9 -0.6 -0.8 0.5 0.6 0.7 0.9 -1.4 -1.0
Comparative body size at age 10 0.2 0.6 2.8 0.4 0.0 -0.7 0.6 0.0 1.7 -0.8 0.2
Number of full brothers 1.4 1.8 3.6 -1.3 -1.9 -1.4 -1.3 -1.3 -1.5 1.1 0.4
Worry too long after embarrassment 2.3 3.9 8.0 0.7 1.1 2.8 2.1 2.0 2.4 -2.2 -1.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 1.6 -1.0 0.7 1.3 -0.5 -0.4 0.9 -0.7 -0.6
Wheeze or whistling in the chest in last year 0.5 0.9 2.0 -0.6 -1.4 0.7 -1.1 -0.8 -1.4 0.7 -0.2
Number of children fathered 0.6 0.7 3.3 0.0 1.8 0.6 -0.5 -0.2 0.0 -0.3 -1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.3 -1.2 0.3 -0.1 -0.0 -0.3 -0.1 0.2 -0.5
Age at first live birth 0.2 0.4 0.7 -0.2 0.3 -0.8 -0.6 -0.7 0.1 -0.7 -0.9
Pulse wave peak to peak time 2.5 3.0 5.5 1.6 1.2 1.1 2.0 1.7 1.4 -2.0 -2.4
Health satisfaction 0.2 0.3 1.3 -0.2 0.2 0.6 0.6 0.4 1.1 -0.2 0.0
Shortness of breath walking on level ground 0.4 0.5 1.6 0.5 0.8 1.2 0.1 -0.0 0.3 -0.1 -1.2
Qualifications: College or University degree 0.2 0.5 1.4 0.6 -0.5 0.3 0.5 0.4 -0.9 -0.7 -1.2
Eye problems/disorders: None of the above 0.4 0.5 1.2 -0.5 -0.6 -0.9 -0.8 -0.4 -1.1 0.6 0.1
Mouth/teeth dental problems: Loose teeth 2.2 2.6 4.4 0.7 0.5 1.8 1.9 2.0 2.1 -2.0 -0.8
Emphysema/chronic bronchitis 0.5 0.6 1.6 0.8 -1.1 1.2 0.2 0.6 -0.5 0.5 0.7
Medication for pain relief, constipation, heartburn 1.1 1.9 4.3 0.4 -0.3 0.3 1.9 2.1 1.6 -2.0 -0.7
Neck or shoulder pain in last month 0.4 0.6 1.8 -0.0 0.2 -0.1 -1.2 -1.0 -1.4 0.7 0.0
Medication: Blood pressure 0.2 0.3 1.5 0.3 1.2 -0.6 0.2 0.6 0.1 -0.3 0.3
Angina (self-reported) 0.4 0.5 1.8 0.1 0.6 1.1 -0.6 -0.3 -0.5 -0.0 -1.4
Migraine (self-reported) 4.1 5.1 12.5 -1.4 -1.0 -1.8 -3.3 -3.5 -1.9 2.3 1.5
Medication: Ibuprofen 2.0 2.4 5.4 0.4 -1.5 0.0 -1.8 -2.2 -1.7 2.3 0.6
Medication: Allopurinol 1.0 1.3 3.4 -0.9 -0.7 -1.9 -1.2 -1.0 -1.4 1.0 0.1
Medication: Omeprazole 0.2 0.2 0.9 -0.4 0.1 -0.9 -0.2 0.1 -0.4 0.4 0.6
Medication: Seretide 50 evohaler 0.4 0.5 2.0 -1.4 -1.0 -0.6 -0.2 -0.2 -0.5 0.3 0.6
Mean time to correctly identify matches 2.2 4.2 7.7 2.3 2.8 2.0 2.1 2.6 1.4 -1.4 -1.2
Heart disease (mother) 0.3 0.3 1.4 -0.5 1.2 0.9 -0.0 -0.2 -0.1 0.4 0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 1.8 0.1 0.4 1.4 0.5 0.4 0.2 0.1 0.0
Whole body fat mass 0.1 0.3 0.9 -0.9 0.1 -0.4 -0.6 -0.6 0.2 0.0 0.6
Leg fat mass (right) 0.1 0.4 1.1 -1.0 0.1 -0.5 -0.7 -0.8 0.4 0.1 1.0
Arm predicted mass (right) 4.6 23.5 38.4 -3.9 -4.0 -3.9 -6.1 -6.2 -5.3 4.8 3.9
Pulse rate, automated reading 0.2 0.6 3.6 -0.5 1.9 0.1 -0.0 0.0 0.6 -0.4 0.0
Alcohol intake frequency. 1.2 2.9 5.3 -0.6 -2.0 -0.7 -2.0 -2.0 -1.6 2.3 1.4
Comparative height size at age 10 1.2 6.6 11.7 -0.6 -3.4 -1.2 -2.7 -2.6 -3.4 2.9 2.2
Number of full sisters 1.1 1.3 1.9 -0.7 -1.4 -1.4 -1.2 -0.9 -1.2 1.1 1.2
Suffer from ‘nerves’ 0.8 1.3 3.3 0.0 -0.4 0.7 1.6 1.5 1.8 -1.2 -0.1
Overall health rating 0.4 1.0 4.0 0.2 1.3 0.7 0.4 0.5 2.0 -1.0 0.2
Chest pain or discomfort 0.2 0.3 1.3 0.0 0.0 -0.1 -0.8 -0.5 -1.1 0.4 -0.2
Had major operations 0.4 0.5 1.3 -1.1 0.8 1.1 0.5 0.5 0.2 -0.1 -0.5
Age at last live birth 0.4 0.6 1.8 -0.8 0.9 0.1 0.3 0.3 0.7 -1.4 -1.1
Family relationship satisfaction 0.2 0.2 0.8 -0.6 -0.0 0.9 0.3 0.7 0.0 -0.5 -0.2
Leg pain on walking 1.5 1.9 4.1 0.2 -0.5 -0.8 -2.0 -2.0 -1.4 1.5 1.2
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.7 6.4 -0.8 -0.4 -1.2 -1.2 -0.9 -0.9 1.4 2.5
Commuting to job workplace: Car/motor vehicle 0.9 1.1 2.6 -0.2 0.7 -1.2 -1.6 -1.6 -0.6 0.7 0.7
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.8 -0.3 -0.5 0.4 -0.1 0.1 0.3 0.3 1.4
Medication: Aspirin 0.2 0.3 1.0 -1.0 0.6 0.3 -0.7 -0.8 0.0 0.0 0.1
Supplements: Vitamin C 0.7 0.8 2.7 0.2 0.4 -0.0 1.4 1.6 0.8 -0.6 -0.9
Knee pain experienced in last month 0.2 0.3 1.1 -1.0 0.8 0.3 -0.1 -0.4 0.4 0.1 -0.2
Hypertension (Self-reported) 0.1 0.2 0.9 -0.2 0.3 -0.1 -0.4 0.2 0.7 -0.5 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.3 3.0 1.7 0.5 1.6 1.4 1.4 0.7 -0.6 -0.2
Illnesses of father: Heart disease 0.5 0.8 4.6 0.3 -0.1 2.1 0.0 0.1 -0.9 0.2 -0.8
Illnesses of siblings: Diabetes 0.9 1.1 3.2 1.3 0.8 1.8 1.0 1.0 0.8 -0.6 -0.5
Smoking status: Previous 0.3 0.5 1.6 0.5 -1.2 1.3 0.6 0.6 -0.1 -0.1 0.3
Forced expiratory volume in 1-second (FEV1), predicted 2.5 5.2 21.2 -1.8 -4.6 -1.0 -2.0 -1.9 -2.2 1.8 0.9
Whole body fat-free mass 4.8 27.2 43.0 -3.8 -4.5 -4.1 -6.6 -6.5 -5.7 5.5 4.4
Leg fat-free mass (right) 3.7 19.6 31.9 -3.3 -3.4 -3.7 -5.6 -5.6 -4.7 4.5 3.8
Arm fat percentage (left) 0.2 0.8 2.3 -0.5 1.4 0.3 0.7 0.6 1.5 -0.8 0.2
Average weekly red wine intake 0.7 1.0 1.6 -0.3 1.2 0.6 1.2 1.2 0.7 -1.3 -1.1
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.7 -0.2 -0.6 -1.0 -0.5 -0.5 -0.5 0.7 1.3
Mood swings 0.4 0.6 1.5 0.9 0.3 0.3 0.7 0.4 1.1 -1.2 -0.8
Loneliness, isolation 0.1 0.2 0.4 -0.3 -0.4 0.5 -0.6 -0.3 -0.5 0.5 0.3
Long-standing illness, disability or infirmity 0.6 1.0 2.6 0.4 1.1 1.4 0.9 0.4 1.6 -0.9 -0.2
Ever had bowel cancer screening 1.0 1.1 3.3 0.2 1.3 0.4 1.4 1.8 0.8 -0.6 0.9
Diabetes diagnosed by doctor 0.7 1.2 2.8 -1.0 1.7 1.2 0.4 0.8 1.3 -1.2 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 0.9 0.9 1.7 0.2 0.3 -0.4 -1.3 -0.8 -1.3 1.3 1.3
Friendships satisfaction 0.4 0.5 1.9 -0.5 -0.5 0.5 -0.4 0.0 -0.4 1.0 1.4
Qualifications: nursing, teaching 1.4 2.2 3.5 -1.9 1.1 -1.8 -1.8 -1.6 -0.9 0.7 1.7
Commuting to job workplace: Walk 0.8 0.9 2.7 -0.1 0.3 1.2 1.4 1.6 0.6 -0.5 -0.2
Eye problems/disorders: Cataract 0.3 0.3 0.6 0.7 -0.8 0.4 -0.5 -0.8 -0.1 0.5 0.7
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 5.5 0.8 2.3 -0.0 0.5 0.4 -0.1 0.1 -1.0
Medication for cholesterol 0.7 1.1 2.5 0.6 0.2 0.4 1.5 1.2 0.8 -1.1 -1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.7 2.0 5.0 1.1 2.2 0.3 1.8 1.7 1.5 -1.1 -0.4
Back pain experienced in last month 1.9 2.8 5.4 -0.5 -0.3 -1.5 -1.8 -1.9 -1.6 2.2 2.3
Mineral and other dietary supplements 0.6 0.8 2.3 0.2 -1.5 -0.9 -1.2 -0.9 -0.8 0.6 0.2
Breast cancer (self-reported) 0.9 1.1 2.7 -1.3 0.2 -0.8 -1.0 -1.2 0.0 1.2 1.6
Asthma (self-reported) 0.2 0.4 1.5 -1.2 -0.0 0.9 -0.4 0.0 -0.5 0.3 -0.6
Osteoporosis (self-reported) 0.5 0.6 1.9 -0.4 1.4 -0.5 0.7 1.1 0.4 -0.6 0.3
Osteoarthritis (self-reported) 1.0 1.3 2.6 -1.0 0.0 -1.0 -1.0 -1.5 -1.1 1.6 1.1
Medication: Aspirin 0.2 0.3 1.0 -1.0 0.8 0.5 -0.2 -0.3 0.4 -0.4 -0.3
Medication: Gliclazide 0.8 0.9 1.9 -0.6 0.3 0.5 1.1 1.4 1.2 -1.1 -0.7
Illnesses of father: None of the above (group 1) 0.9 1.1 2.9 -1.4 0.7 -0.9 1.0 0.6 1.7 -1.0 0.0
Smoking status: Current 3.0 4.8 7.2 -2.2 -2.1 -2.2 -2.7 -2.5 -2.2 2.1 1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 1.2 -0.9 -0.9 -0.9 -0.7 -1.1 0.1 0.2 1.1
Whole body water mass 4.8 27.6 43.1 -3.8 -4.5 -4.1 -6.6 -6.5 -5.8 5.5 4.4
Leg predicted mass (right) 3.7 19.8 32.1 -3.3 -3.5 -3.7 -5.7 -5.6 -4.8 4.5 3.8
Arm fat mass (left) 0.5 2.2 4.0 -2.0 -0.5 -1.4 -1.8 -1.9 -0.7 1.2 1.7
Number of self-reported non-cancer illnesses 0.8 1.3 2.5 -1.6 -0.3 -0.3 -1.4 -1.1 -0.8 1.4 1.5
Average weekly champagne plus white wine intake 0.6 0.8 3.1 0.3 -0.5 0.4 1.3 1.8 0.4 -0.9 -0.1
Miserableness 0.3 0.6 1.5 -1.2 -1.2 0.3 -0.8 -0.9 -0.2 0.2 0.1
Guilty feelings 2.2 3.3 5.3 1.8 0.4 2.3 2.1 2.0 1.5 -1.7 -2.2
Wears glasses or contact lenses 0.9 1.0 1.6 1.0 0.9 1.1 1.3 1.2 1.1 -0.8 -0.4
Ever taken oral contraceptive pill 0.3 0.3 0.8 -0.2 -0.2 0.5 0.5 0.8 0.1 -0.7 -0.9
Hearing aid user 0.2 0.2 1.3 1.2 -0.3 -0.4 0.1 0.2 0.2 -0.3 -0.2
Mother’s age at death 1.2 1.5 4.6 0.9 1.3 -0.3 0.8 0.8 0.9 -1.7 -2.1
Financial situation satisfaction 1.4 1.7 3.2 1.4 1.8 0.9 0.9 1.2 1.1 -1.5 -1.6
Tinnitus: Yes, now most or all of the time 1.0 1.2 3.1 -0.6 -1.8 -1.0 -0.7 -1.0 -1.1 1.2 0.9
Commuting to job workplace: Public transport 1.3 1.5 2.8 0.9 1.0 1.0 1.5 1.7 1.0 -1.7 -0.9
Eye problems/disorders: Glaucoma 0.1 0.1 0.3 0.5 -0.0 -0.5 0.5 0.5 0.2 -0.1 0.0
Medication: Blood pressure 0.4 0.7 2.1 -0.6 0.2 0.5 -1.2 -0.9 -0.1 0.5 1.4
Pain type(s) experienced in last month: Hip pain 0.5 0.6 1.2 -0.3 -0.4 0.5 -0.9 -1.1 -0.8 0.9 0.9
Supplements: Fish oil (including cod liver oil) 0.5 0.7 1.9 0.2 0.4 1.1 1.1 0.7 0.5 -0.3 -1.4
High cholesterol (Self-reported) 0.1 0.2 0.7 -0.7 -0.4 0.8 0.5 0.3 0.2 -0.1 -0.2
Medication: Bendroflumethiazide 0.3 0.5 1.6 0.2 1.1 0.7 -0.0 0.3 1.2 -0.7 0.0
Medication: Paracetamol 0.4 0.6 1.7 0.8 1.3 0.7 -0.3 -0.4 -0.8 1.2 0.3
Medication: Lisinopril 0.3 0.4 1.2 -1.1 -0.2 -0.7 -0.9 -0.4 -0.4 0.1 0.2
Medication: Atorvastatin 1.3 1.6 4.2 -2.0 -1.5 0.0 -0.8 -0.8 -1.5 1.3 0.9
Illnesses of father: High blood pressure 3.7 4.6 8.6 -1.2 -1.6 -2.6 -2.9 -2.2 -2.4 2.1 1.6
Alcohol drinker status: Never 0.5 0.5 1.2 0.6 -1.1 0.6 -0.6 -0.6 -1.0 0.7 -0.3
Ever smoked 0.9 1.5 3.3 -1.6 -1.8 -0.8 -1.1 -1.2 -0.8 0.8 1.2
Basal metabolic rate 3.9 21.4 33.7 -3.4 -3.9 -3.6 -5.8 -5.8 -5.0 4.9 4.0
Leg fat percentage (left) 0.5 1.8 4.5 -0.2 1.5 1.0 1.4 1.2 2.1 -1.7 -0.6
Arm fat-free mass (left) 4.5 22.6 37.2 -3.7 -4.0 -3.4 -6.0 -6.1 -5.2 4.9 3.9
Number of operations (self-reported) 0.5 0.7 1.8 -1.0 0.8 0.4 -0.6 -0.1 -1.3 1.0 0.8
Average weekly beer plus cider intake 0.2 0.4 1.0 -0.6 0.5 0.3 0.5 0.1 0.8 -0.5 -1.0
Irritability 0.5 0.8 4.1 -0.5 0.2 0.6 0.1 0.2 2.0 -1.2 -0.3
Risk taking 0.4 0.6 2.4 -0.9 1.5 0.4 0.2 0.7 0.1 -0.7 -0.8
Ever had prostate specific antigen (PSA) test 3.3 3.8 5.5 -1.1 -1.7 -2.3 -2.0 -2.0 -1.8 2.3 1.9
Fractured/broken bones in last 5 years 0.4 0.5 2.9 -0.4 1.7 -0.3 -0.2 0.1 -0.8 -0.2 -0.3
Age started oral contraceptive pill 0.6 0.8 2.0 -0.2 0.1 -0.1 -1.0 -0.7 -1.3 1.2 1.4
Diastolic blood pressure, automated reading 0.7 2.2 6.3 -0.9 -0.8 -2.5 -1.6 -1.8 -0.7 1.1 1.4
Ever depressed for a whole week 0.1 0.2 0.4 0.3 0.4 -0.2 0.5 0.6 0.4 -0.1 -0.5
Unable to work because of sickness or disability 0.3 0.4 1.2 0.3 -0.1 1.1 0.7 0.8 0.5 0.2 0.8
Commuting to job workplace: Cycle 1.4 1.7 4.0 -0.5 1.5 0.7 2.0 1.9 1.3 -0.9 -0.6
Myopia 0.2 0.3 0.7 0.2 0.1 -0.0 0.7 0.8 0.6 -0.5 0.6
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.5 0.4 0.2 -0.1 0.6 0.0 -0.4 0.4 -0.7
Cholesterol lowering medication 1.1 1.6 5.2 -2.3 -0.8 -0.6 -1.3 -1.3 -0.8 1.0 1.3
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 0.9 0.0 0.9 0.0 0.5 0.9 0.2 -0.6 -0.5
Pain experienced in last month 0.3 0.5 0.9 0.7 -0.7 -0.6 0.9 1.0 0.5 -0.6 -0.1
Supplements: Calcium 0.6 0.7 2.5 -0.1 0.9 -0.4 0.3 0.3 -0.5 1.2 1.6
Basal cell carcinoma (self-reported) 1.3 1.5 3.4 0.9 0.0 1.1 1.6 1.5 1.9 -0.6 1.3
Heart attack/myocardial infarction (self-reported) 0.4 0.5 2.6 -0.9 -0.4 1.6 -0.6 0.0 -0.3 -0.3 -0.1
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 2.4 -0.7 -1.1 0.2 -0.7 -0.7 -1.5 1.6 1.3
Heart disease (siblings) 0.4 0.5 3.1 -0.1 1.8 0.0 -0.1 0.0 -0.5 0.5 -0.1
Alcohol drinker status: Previous 1.3 1.5 2.6 -1.6 -1.4 -0.1 -0.9 -1.2 0.1 1.6 1.6
Pack years of smoking 0.8 1.2 2.7 -1.0 -1.4 -0.8 -1.5 -1.6 -0.6 0.6 0.4
Impedance of whole body 5.2 26.2 48.7 4.2 2.4 4.0 6.7 7.0 5.0 -5.6 -4.6
Leg fat mass (left) 0.2 0.7 1.8 -1.3 0.0 -0.8 -0.9 -1.1 0.1 0.2 1.0
Arm predicted mass (left) 4.7 24.1 40.6 -4.0 -4.0 -3.6 -6.3 -6.4 -5.2 5.0 3.9