[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr22:39,064,209-41,004,384

Best TWAS P=2.75e-08 · Best GWAS P=1.03e-08 conditioned to 0.0537

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Skin Sun Exposed Lower leg	MGAT3	0.13	0.05	lasso	3	0.02	4.7e-03	-5.4	5.6	2.8e-08	0.01	0.01	0.98	TRUE
8	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADSL	0.09	0.03	lasso	3	0.01	7.7e-02	-5.7	-5.5	4.0e-08	0.91	0.00	0.76	TRUE
2	GTEx	Heart Atrial Appendage	MGAT3	0.14	0.14	lasso	2	0.12	3.5e-06	-5.4	5.5	3.9e-08	0.02	0.01	0.98	FALSE
7	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADSL	0.06	0.02	lasso	2	0.03	6.6e-03	-5.5	-5.5	4.5e-08	0.97	0.00	0.81	FALSE
6	The Cancer Genome Atlas	Lung Adenocarcinoma	ADSL	0.03	0.00	blup	33	0.01	8.9e-03	-5.4	-5.2	1.7e-07	0.82	0.01	0.61	FALSE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADSL	0.04	0.03	enet	6	0.03	1.6e-04	-5.6	-5.2	2.1e-07	0.86	0.00	0.94	FALSE
1	GTEx	Adipose Subcutaneous	MGAT3	0.08	0.04	lasso	4	0.04	4.3e-04	-5.6	5.1	3.0e-07	0.04	0.01	0.98	FALSE
3	GTEx	Nerve Tibial	SYNGR1	0.26	0.18	enet	27	0.21	3.6e-15	-4.1	-5.1	3.0e-07	-0.04	0.07	0.93	FALSE