[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr2:35,883,253-37,567,226

Best TWAS P=1.56e-12 · Best GWAS P=1.7e-12 conditioned to 0.0597

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	CRIM1	0.10	0.04	lasso	4	0.05	1.4e-04	6.2	-7.1	1.6e-12	-0.86	0.02	0.98	TRUE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	FEZ2	0.01	0.01	blup	85	0.01	1.0e-03	6.0	-7.1	1.7e-12	-0.90	0.01	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FEZ2	0.16	0.24	lasso	2	0.22	1.3e-26	6.9	-6.9	5.0e-12	-0.97	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	AC007401.1	0.10	0.02	lasso	4	0.02	5.4e-03	6.2	6.9	5.2e-12	0.87	0.02	0.96	FALSE
12	GTEx	Spleen	FEZ2	0.42	0.16	enet	25	0.17	3.9e-05	5.8	6.9	6.0e-12	0.66	0.04	0.89	FALSE
4	GTEx	Artery Tibial	RP11-78I14.1	0.10	0.08	enet	16	0.07	4.2e-06	6.2	-6.8	9.2e-12	-0.71	0.12	0.83	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	FEZ2	0.06	0.05	blup	87	0.08	1.4e-08	6.2	-6.6	3.4e-11	-0.91	0.08	0.92	FALSE
5	GTEx	Brain Cerebellar Hemisphere	CRIM1	0.36	0.21	lasso	5	0.16	5.4e-05	6.4	6.5	7.1e-11	0.85	0.05	0.87	FALSE
10	GTEx	Brain Cerebellum	AC007401.1	0.27	0.21	enet	5	0.20	1.5e-06	6.4	6.3	2.2e-10	0.86	0.08	0.88	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	FEZ2	0.41	0.55	lasso	5	0.58	3.1e-93	6.2	-6.3	2.8e-10	-0.93	0.36	0.64	FALSE
13	GTEx	Whole Blood	AC007401.1	0.06	0.06	lasso	5	0.05	4.6e-05	6.0	6.2	4.1e-10	0.89	0.12	0.84	FALSE
7	GTEx	Brain Cerebellar Hemisphere	AC007401.1	0.40	0.26	lasso	4	0.22	2.3e-06	6.4	6.2	4.5e-10	0.87	0.06	0.92	FALSE
8	GTEx	Brain Cerebellar Hemisphere	RP11-490M8.1	0.37	0.18	lasso	4	0.15	1.2e-04	6.0	6.2	6.6e-10	0.90	0.03	0.88	FALSE
6	GTEx	Brain Cerebellar Hemisphere	FEZ2	0.41	0.30	lasso	6	0.28	8.6e-08	6.0	6.1	8.5e-10	0.89	0.04	0.95	FALSE
17	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FEZ2	0.06	0.05	lasso	4	0.04	3.3e-03	6.2	-6.1	9.7e-10	-0.92	0.04	0.83	FALSE
14	NTR	Blood	CRIM1	0.09	0.10	lasso	6	0.11	3.1e-32	6.0	-6.1	1.2e-09	-0.91	0.21	0.79	FALSE
11	GTEx	Brain Cerebellum	RP11-490M8.1	0.21	0.21	lasso	4	0.20	1.4e-06	5.8	6.0	2.6e-09	0.82	0.05	0.92	FALSE
9	GTEx	Brain Cerebellum	FEZ2	0.44	0.26	lasso	6	0.23	2.6e-07	5.6	5.8	5.6e-09	0.84	0.19	0.80	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FEZ2	0.11	0.03	blup	84	0.07	6.1e-05	6.9	-5.7	1.3e-08	-0.89	0.02	0.96	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	FEZ2	0.07	0.06	blup	87	0.06	2.4e-06	6.0	-5.4	7.5e-08	-0.80	0.39	0.60	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FEZ2	0.18	0.21	lasso	6	0.21	5.3e-08	-4.2	-5.3	8.6e-08	-0.67	0.15	0.82	FALSE
19	The Cancer Genome Atlas	Esophageal Carcinoma	FEZ2	0.11	0.01	blup	87	0.02	7.1e-02	5.6	-5.2	1.9e-07	-0.80	0.05	0.25	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FEZ2	0.04	0.00	blup	88	0.02	6.1e-03	5.7	-5.2	2.1e-07	-0.83	0.02	0.86	FALSE