[Hub]/) : Traits : Leg fat-free mass (left) :

chr1:25,752,617-27,488,299

Best TWAS P=5.36e-11 · Best GWAS P=1.69e-10 conditioned to 0.848

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa PDIK1L 0.10 0.09 lasso 6 0.09 8.8e-07 6.1 -5.9 3.0e-09 -0.95 0.02 0.98 FALSE
2 GTEx Thyroid DHDDS 0.14 0.08 enet 22 0.07 5.8e-06 5.4 -5.2 2.5e-07 -0.14 0.44 0.36 TRUE
3 GTEx Thyroid CNKSR1 0.10 0.04 lasso 7 0.03 2.1e-03 5.2 -5.6 2.4e-08 -0.73 0.11 0.87 FALSE
4 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM63 0.03 0.02 blup 33 0.02 4.6e-03 6.3 6.0 2.4e-09 0.91 0.01 0.89 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM63 0.15 0.16 lasso 2 0.16 2.3e-32 6.3 6.3 2.5e-10 0.97 0.00 1.00 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM63 0.14 0.15 lasso 1 0.14 2.2e-07 6.3 6.3 3.6e-10 0.95 0.00 1.00 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma TRIM63 0.08 0.10 lasso 4 0.10 3.7e-06 6.1 5.8 8.6e-09 0.95 0.01 0.99 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GRRP1 0.11 0.02 blup 52 0.03 8.8e-05 -2.9 5.2 2.7e-07 0.47 0.02 0.27 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDIK1L 0.02 0.02 blup 37 0.02 2.8e-03 6.2 -6.2 4.2e-10 -0.93 0.01 0.83 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIM63 0.11 0.11 enet 4 0.12 9.0e-14 6.1 5.5 5.1e-08 0.95 0.00 1.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma PDIK1L 0.03 0.01 blup 37 0.02 2.6e-03 5.2 -6.6 5.4e-11 -0.85 0.01 0.55 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma TRIM63 0.29 0.33 enet 20 0.33 2.5e-38 6.1 6.4 1.7e-10 0.92 0.01 0.99 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma TRIM63 0.14 0.20 enet 7 0.21 9.4e-24 6.1 5.7 1.6e-08 0.95 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRIM63 0.16 0.11 lasso 1 0.10 2.0e-11 6.1 6.1 9.4e-10 0.96 0.01 0.99 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM63 0.14 0.18 lasso 7 0.15 3.0e-10 6.0 5.8 5.3e-09 0.95 0.01 0.99 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma SH3BGRL3 0.05 0.03 lasso 2 0.03 9.3e-04 4.9 5.3 1.4e-07 0.56 0.02 0.68 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma TRIM63 0.18 0.26 enet 7 0.26 3.0e-25 6.1 6.0 2.0e-09 0.94 0.01 0.99 FALSE
18 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma TRIM63 0.19 0.07 blup 33 0.14 1.3e-04 6.1 5.5 4.4e-08 0.88 0.01 0.99 FALSE