[Hub]/) : Traits : Leg predicted mass (left) :

chr9:97,520,168-101,477,500

Best TWAS P=6.48e-16 · Best GWAS P=5.15e-19 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC441454 0.05 0.01 lasso 3 0.02 1.5e-03 5.21 5.4 5.7e-08 0.04 0.05 0.47 FALSE
2 GTEx Artery Tibial RP11-435O5.5 0.09 0.04 lasso 2 0.02 7.3e-03 8.27 -8.1 6.5e-16 -0.95 0.02 0.93 TRUE
3 GTEx Breast Mammary Tissue CDC14B 0.16 0.02 enet 21 0.02 3.7e-02 6.10 -5.2 1.6e-07 -0.02 0.13 0.73 FALSE
4 GTEx Cells EBV-transformed lymphocytes AAED1 0.17 0.02 lasso 3 0.04 2.4e-02 6.09 5.3 1.0e-07 0.02 0.06 0.35 FALSE
5 GTEx Liver PTCH1 0.25 0.06 enet 11 0.03 4.9e-02 8.61 5.7 1.2e-08 0.26 0.04 0.74 FALSE
6 GTEx Nerve Tibial ZNF367 0.10 0.05 lasso 3 0.02 7.9e-03 6.37 5.6 1.8e-08 0.04 0.08 0.88 FALSE
7 GTEx Spleen PTCH1 0.33 0.08 lasso 8 0.18 1.9e-05 -0.48 5.1 2.7e-07 0.28 0.11 0.42 TRUE
8 GTEx Testis HABP4 0.19 0.22 lasso 9 0.21 1.1e-09 6.24 6.2 4.7e-10 0.04 0.12 0.88 FALSE
9 GTEx Thyroid CDC14B 0.15 0.10 lasso 5 0.08 5.3e-07 5.85 -6.0 1.7e-09 -0.04 0.32 0.68 FALSE
10 NTR Blood PTCH1 0.04 0.02 blup 433 0.02 4.1e-08 6.21 5.6 1.9e-08 0.09 0.08 0.92 TRUE
11 YFS Blood ANP32B 0.03 0.02 lasso 9 0.02 1.9e-08 -5.03 5.7 1.0e-08 0.00 0.00 0.99 TRUE
12 YFS Blood HABP4 0.08 0.09 enet 24 0.11 5.9e-34 6.55 -5.8 6.1e-09 -0.09 0.02 0.98 FALSE
13 YFS Blood PTCH1 0.09 0.05 lasso 8 0.05 1.2e-15 6.18 6.8 1.3e-11 0.42 0.14 0.86 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma CDC14B 0.02 0.01 lasso 1 0.01 3.0e-03 6.35 -6.4 2.1e-10 -0.04 0.04 0.38 FALSE
15 The Cancer Genome Atlas Glioblastoma Multiforme CDC14B 0.16 0.17 blup 41 0.19 2.6e-06 6.09 -5.4 5.6e-08 -0.01 0.09 0.86 FALSE
16 The Cancer Genome Atlas Glioblastoma Multiforme HABP4 0.08 0.06 blup 44 0.05 1.6e-02 5.74 -6.5 8.7e-11 -0.06 0.03 0.49 FALSE
17 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HABP4 0.02 0.02 blup 44 0.02 7.1e-03 6.09 6.5 9.4e-11 0.04 0.04 0.56 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDC14B 0.03 0.02 blup 42 0.02 2.1e-03 6.09 -6.4 1.3e-10 -0.04 0.06 0.41 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma CDC14B 0.05 0.06 lasso 5 0.06 6.5e-07 6.05 -5.3 1.1e-07 -0.04 0.19 0.81 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma HABP4 0.05 0.08 lasso 5 0.08 6.9e-09 5.67 -5.8 5.8e-09 -0.05 0.26 0.74 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma PTCH1 0.02 0.01 blup 54 0.02 1.1e-03 7.04 -7.0 2.0e-12 -0.86 0.02 0.70 FALSE
22 The Cancer Genome Atlas Stomach Adenocarcinoma CDC14B 0.08 0.02 blup 41 0.04 1.0e-03 5.21 -7.0 2.9e-12 -0.08 0.03 0.55 TRUE
23 The Cancer Genome Atlas Thyroid Carcinoma CDC14B 0.05 0.07 blup 42 0.08 4.8e-08 6.15 -6.2 7.0e-10 -0.03 0.13 0.87 FALSE