[Hub]/) : Traits : Leg predicted mass (left) :

chr9:93,476,005-96,338,382

Best TWAS P=1.19e-10 · Best GWAS P=5.72e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum ZNF484 0.21 0.01 lasso 9 0.01 1.7e-01 -5.9 -5.2 1.9e-07 -0.04 0.05 0.58 FALSE
2 GTEx Esophagus Mucosa CENPP 0.09 0.01 lasso 5 0.02 2.1e-02 -4.1 5.1 2.8e-07 0.06 0.07 0.85 FALSE
3 GTEx Esophagus Muscularis BICD2 0.09 0.02 enet 26 0.07 5.0e-05 -4.4 -5.6 2.6e-08 -0.02 0.05 0.75 FALSE
4 GTEx Heart Left Ventricle ECM2 0.07 0.05 lasso 3 0.02 3.1e-02 -5.7 -5.7 1.1e-08 0.00 0.04 0.87 TRUE
5 GTEx Testis NFIL3 0.47 0.33 enet 8 0.29 3.8e-13 -6.6 6.4 1.2e-10 -0.99 0.00 1.00 TRUE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma IPPK 0.06 0.03 blup 49 0.04 5.8e-03 -5.3 5.2 1.8e-07 0.05 0.01 0.62 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma BICD2 0.10 0.03 blup 52 0.03 1.3e-02 -5.9 -5.4 7.1e-08 -0.03 0.01 0.70 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma BICD2 0.06 0.02 blup 52 0.05 2.9e-06 -5.7 -5.4 6.3e-08 -0.04 0.02 0.98 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma ECM2 0.10 0.04 lasso 2 0.04 4.2e-05 -5.2 -5.3 1.1e-07 -0.03 0.00 0.98 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IPPK 0.03 0.02 blup 51 0.01 3.2e-02 -5.3 5.4 8.1e-08 0.06 0.03 0.64 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors CENPP 0.19 0.09 blup 158 0.08 7.1e-04 -5.3 5.3 1.5e-07 0.09 0.02 0.78 FALSE