[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr10:75,189,586-80,383,574

Best TWAS P=5.63e-10 · Best GWAS P=1.27e-10 conditioned to 9.93e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	C10orf11	0.24	0.21	lasso	9	0.20	3.3e-16	5.5	-5.9	3.3e-09	0.03	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	DLG5	0.39	0.40	lasso	12	0.43	1.9e-38	-5.2	-5.1	3.0e-07	0.78	0.56	0.44	FALSE
3	GTEx	Adipose Visceral Omentum	C10orf11	0.40	0.32	enet	11	0.27	2.2e-14	5.5	-6.1	1.2e-09	0.02	0.02	0.98	FALSE
4	GTEx	Adipose Visceral Omentum	DLG5	0.26	0.23	lasso	8	0.21	5.7e-11	-5.2	-5.1	2.7e-07	0.79	0.49	0.51	FALSE
5	GTEx	Adrenal Gland	C10orf11	0.24	0.22	enet	21	0.18	5.8e-07	5.5	-5.3	1.2e-07	0.02	0.02	0.98	FALSE
6	GTEx	Adrenal Gland	DLG5	0.22	0.14	lasso	6	0.11	8.5e-05	-5.2	-5.5	4.2e-08	0.74	0.30	0.51	FALSE
7	GTEx	Artery Aorta	DLG5	0.26	0.19	enet	10	0.22	2.6e-12	-4.9	-5.6	2.5e-08	0.82	0.39	0.61	FALSE
8	GTEx	Artery Aorta	RP13-39P12.3	0.14	0.13	enet	9	0.12	2.2e-07	-4.9	-5.4	6.3e-08	0.82	0.08	0.92	FALSE
9	GTEx	Artery Tibial	DLG5	0.24	0.18	lasso	5	0.18	9.7e-14	-5.2	-5.1	2.8e-07	0.79	0.56	0.44	FALSE
10	GTEx	Cells Transformed fibroblasts	DLG5	0.25	0.18	lasso	11	0.16	2.0e-12	-5.3	-5.5	4.5e-08	0.83	0.18	0.82	FALSE
11	GTEx	Cells Transformed fibroblasts	RP13-39P12.3	0.19	0.13	lasso	7	0.15	4.5e-11	-5.3	-5.2	2.6e-07	0.77	0.36	0.64	FALSE
12	GTEx	Colon Transverse	DLG5	0.23	0.17	lasso	8	0.19	1.4e-09	-5.2	-5.1	3.0e-07	0.80	0.48	0.51	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	DLG5	0.27	0.03	enet	13	0.06	3.9e-03	-6.4	-5.2	2.6e-07	0.75	0.00	0.98	FALSE
14	GTEx	Esophagus Muscularis	C10orf11	0.45	0.39	enet	42	0.38	5.1e-24	5.5	-6.1	1.0e-09	0.01	0.04	0.96	FALSE
15	GTEx	Heart Atrial Appendage	DLG5	0.32	0.23	lasso	4	0.24	3.9e-11	-5.0	-5.2	2.1e-07	0.82	0.55	0.45	FALSE
16	GTEx	Lung	C10orf11	0.30	0.26	lasso	5	0.24	2.0e-18	5.5	-5.9	3.5e-09	0.03	0.03	0.97	FALSE
17	GTEx	Lung	DLG5	0.41	0.38	lasso	8	0.37	7.9e-30	-5.2	-5.2	1.5e-07	0.82	0.59	0.41	FALSE
18	GTEx	Nerve Tibial	DLG5	0.51	0.44	lasso	6	0.50	1.4e-39	-5.2	-5.6	2.5e-08	0.86	0.57	0.43	TRUE
19	GTEx	Nerve Tibial	RP13-39P12.3	0.31	0.25	lasso	7	0.36	1.3e-26	-5.2	-5.2	1.9e-07	0.80	0.26	0.74	FALSE
20	GTEx	Ovary	DLG5	0.62	0.38	lasso	6	0.40	5.3e-11	-5.3	-5.5	3.9e-08	0.76	0.54	0.45	FALSE
21	GTEx	Ovary	RP13-39P12.3	0.42	0.29	lasso	5	0.33	7.5e-09	-5.3	-5.4	8.4e-08	0.75	0.44	0.44	FALSE
22	GTEx	Pancreas	DLG5	0.39	0.43	enet	11	0.44	3.5e-20	-5.2	-5.2	2.3e-07	0.80	0.59	0.41	FALSE
23	GTEx	Pancreas	RP13-39P12.3	0.20	0.24	lasso	3	0.23	3.8e-10	-5.2	-5.2	2.3e-07	0.79	0.53	0.47	FALSE
24	GTEx	Pituitary	DLG5	0.45	0.36	lasso	11	0.31	1.9e-08	-5.3	-5.4	5.7e-08	0.83	0.06	0.93	FALSE
25	GTEx	Pituitary	RP13-39P12.3	0.38	0.22	lasso	11	0.17	3.8e-05	-5.3	-5.4	7.5e-08	0.83	0.03	0.93	FALSE
26	GTEx	Skin Sun Exposed Lower leg	DLG5	0.12	0.06	lasso	4	0.06	4.9e-06	-5.2	-5.2	2.2e-07	0.78	0.29	0.69	FALSE
27	GTEx	Spleen	DLG5	0.51	0.46	lasso	4	0.44	1.1e-12	-5.2	-5.2	1.7e-07	0.80	0.46	0.54	FALSE
28	GTEx	Spleen	RP13-39P12.3	0.38	0.34	lasso	2	0.35	8.8e-10	-5.2	-5.2	2.6e-07	0.76	0.30	0.68	FALSE
29	GTEx	Stomach	DLG5	0.20	0.12	lasso	7	0.08	1.3e-04	-5.2	-5.2	2.5e-07	0.79	0.33	0.58	FALSE
30	GTEx	Thyroid	C10orf11	0.38	0.21	lasso	9	0.25	6.7e-19	5.2	-6.2	5.6e-10	0.02	0.05	0.95	TRUE
31	GTEx	Thyroid	DLG5	0.39	0.43	lasso	5	0.43	1.5e-35	-5.2	-5.1	2.6e-07	0.79	0.60	0.40	FALSE
32	GTEx	Thyroid	RP13-39P12.3	0.28	0.30	lasso	8	0.29	3.3e-22	-5.2	-5.2	1.7e-07	0.79	0.59	0.41	FALSE
33	METSIM	Adipose	C10orf11	0.11	0.10	enet	14	0.10	1.1e-14	5.2	-5.4	5.3e-08	0.02	0.08	0.92	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	ZNF503-AS2	0.07	0.06	lasso	2	0.06	2.2e-08	5.0	5.3	1.5e-07	0.02	0.28	0.72	FALSE
35	YFS	Blood	AP3M1	0.27	0.11	lasso	5	0.15	1.5e-45	3.9	5.2	1.7e-07	-0.01	0.90	0.08	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	VCL	0.02	0.00	blup	57	0.01	5.7e-04	5.6	-5.3	1.1e-07	-0.06	0.01	0.89	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	VCL	0.04	0.03	lasso	1	0.02	5.8e-04	5.5	-5.5	4.3e-08	-0.08	0.00	0.94	TRUE