[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr22:38,447,444-41,004,384

Best TWAS P=1.8e-08 · Best GWAS P=1.06e-08 conditioned to 0.0491

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MGAT3 0.08 0.04 lasso 4 0.04 4.3e-04 -5.6 5.2 2.4e-07 0.04 0.01 0.98 FALSE
2 GTEx Heart Atrial Appendage MGAT3 0.14 0.14 lasso 2 0.12 3.5e-06 -5.5 5.6 2.6e-08 0.02 0.01 0.98 FALSE
3 GTEx Nerve Tibial SYNGR1 0.26 0.18 enet 27 0.21 3.6e-15 -4.1 -5.2 2.2e-07 -0.04 0.07 0.93 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic SUN2 0.13 0.00 enet 36 0.02 2.9e-02 3.3 -5.2 2.4e-07 -0.01 0.15 0.09 TRUE
5 GTEx Skin Sun Exposed Lower leg MGAT3 0.13 0.05 lasso 3 0.02 4.7e-03 -5.5 5.6 1.8e-08 0.01 0.01 0.98 TRUE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADSL 0.04 0.03 enet 6 0.03 1.6e-04 -5.6 -5.2 2.5e-07 0.86 0.00 0.94 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma ADSL 0.03 0.00 blup 33 0.01 8.9e-03 -5.4 -5.2 1.7e-07 0.82 0.01 0.61 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ADSL 0.06 0.02 lasso 2 0.03 6.6e-03 -5.5 -5.5 4.4e-08 0.97 0.00 0.81 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADSL 0.09 0.03 lasso 3 0.01 7.7e-02 -5.7 -5.5 3.7e-08 0.91 0.00 0.75 TRUE