[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr4:85,698,680-88,430,396

Best TWAS P=3.91e-09 · Best GWAS P=7.21e-09 conditioned to 0.319

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPN13 0.13 0.18 bslmm 418 0.18 6.8e-22 5.2 -5.6 2.0e-08 0.10 0.11 0.89 FALSE
2 GTEx Artery Aorta MAPK10 0.15 0.17 enet 16 0.17 1.4e-09 5.6 -5.4 6.7e-08 0.07 0.02 0.98 FALSE
3 GTEx Artery Aorta ARHGAP24 0.24 0.13 enet 8 0.14 2.2e-08 -4.1 -5.3 1.4e-07 0.87 0.02 0.98 FALSE
4 GTEx Artery Aorta RP13-514E23.2 0.26 0.09 lasso 6 0.10 2.2e-06 -5.8 -5.5 3.4e-08 0.90 0.01 0.99 FALSE
5 GTEx Artery Tibial ARHGAP24 0.26 0.19 enet 14 0.21 2.7e-16 -5.8 -5.5 4.9e-08 0.91 0.00 1.00 FALSE
6 GTEx Artery Tibial RP13-514E23.2 0.22 0.16 enet 10 0.18 1.2e-13 -5.8 -5.8 8.1e-09 0.93 0.00 1.00 TRUE
7 GTEx Colon Sigmoid MAPK10 0.25 0.11 lasso 8 0.07 1.6e-03 5.7 -5.9 3.9e-09 0.13 0.03 0.94 TRUE
8 GTEx Thyroid PTPN13 0.41 0.31 lasso 6 0.30 3.2e-23 5.7 5.6 1.9e-08 -0.07 0.01 0.99 FALSE
9 ROSMAP Brain Pre-frontal Cortex PTPN13 0.09 0.03 blup 409 0.07 4.7e-09 5.2 -5.8 6.9e-09 0.10 0.09 0.91 FALSE