[Hub]/) : Traits : Arm fat percentage (right) : ← →

chr17:43,871,147-47,718,188

Best TWAS P=8.36e-13 · Best GWAS P=2.04e-16 conditioned to 0.000199

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	CommonMind	Brain Pre-frontal Cortex	SNF8	0.08	0.07	lasso	5	0.08	9.3e-10	-5.58	7.2	8.4e-13	-0.84	0.08	0.92	TRUE
75	The Cancer Genome Atlas	Prostate Adenocarcinoma	CDK5RAP3	0.06	0.00	blup	62	0.03	1.0e-03	-3.64	-6.8	1.3e-11	0.07	0.01	0.52	TRUE
38	GTEx	Liver	ARL17A	0.34	0.18	lasso	9	0.18	9.8e-06	5.18	6.3	3.7e-10	0.04	0.00	0.94	TRUE
54	GTEx	Skin Not Sun Exposed Suprapubic	UBE2Z	0.11	0.07	lasso	6	0.04	1.8e-03	-6.50	6.6	4.5e-11	-0.68	0.10	0.12	FALSE
37	GTEx	Heart Left Ventricle	ATP5G1	0.24	0.22	lasso	4	0.22	9.3e-12	-6.04	6.6	5.0e-11	-0.64	1.00	0.00	FALSE
48	GTEx	Ovary	ATP5G1	0.15	0.08	enet	13	0.09	2.8e-03	-5.17	6.4	1.5e-10	-0.66	0.06	0.72	FALSE
31	GTEx	Esophagus Muscularis	SNF8	0.08	0.03	lasso	3	0.01	5.7e-02	-6.50	6.4	1.7e-10	-0.71	0.03	0.77	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATP5G1	0.07	0.05	lasso	3	0.06	4.7e-08	-6.20	6.3	2.4e-10	-0.62	0.94	0.06	FALSE
65	GTEx	Thyroid	RP11-6N17.10	0.19	0.12	lasso	5	0.13	3.0e-10	-4.94	-6.3	3.8e-10	0.13	0.90	0.10	FALSE
19	GTEx	Brain Cortex	ARL17A	0.35	0.20	lasso	6	0.25	1.7e-07	5.18	6.2	5.4e-10	0.01	0.00	0.97	FALSE
42	GTEx	Muscle Skeletal	UBE2Z	0.06	0.02	lasso	8	0.03	9.8e-04	-6.04	6.1	9.8e-10	-0.66	0.41	0.47	FALSE
49	GTEx	Pancreas	CDK5RAP3	0.11	-0.01	lasso	4	0.02	5.1e-02	4.67	-6.1	1.1e-09	0.04	0.09	0.18	FALSE
28	GTEx	Esophagus Gastroesophageal Junction	RP11-6N17.9	0.18	0.14	lasso	3	0.09	4.9e-04	-4.94	-6.1	1.3e-09	0.12	0.03	0.73	FALSE
43	GTEx	Muscle Skeletal	AC003665.1	0.05	0.03	enet	8	0.03	1.4e-03	4.81	6.1	1.3e-09	-0.11	0.12	0.73	FALSE
61	GTEx	Thyroid	CDK5RAP3	0.21	0.14	lasso	5	0.18	1.6e-13	-4.94	-6.1	1.4e-09	0.13	0.90	0.10	FALSE
78	The Cancer Genome Atlas	Thyroid Carcinoma	UBE2Z	0.13	0.09	lasso	4	0.12	2.7e-11	-5.44	6.0	2.0e-09	-0.64	0.05	0.95	FALSE
22	GTEx	Cells Transformed fibroblasts	SNF8	0.12	0.10	lasso	3	0.12	5.1e-09	-5.44	6.0	2.3e-09	-0.66	0.99	0.01	FALSE
56	GTEx	Skin Sun Exposed Lower leg	UBE2Z	0.14	0.11	lasso	9	0.14	6.3e-12	-5.21	6.0	2.6e-09	-0.64	1.00	0.00	FALSE
64	GTEx	Thyroid	RP11-6N17.9	0.22	0.14	lasso	5	0.14	5.2e-11	-4.94	-5.9	2.9e-09	0.12	0.90	0.10	FALSE
72	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNF8	0.11	0.12	lasso	4	0.12	1.4e-13	-5.60	5.8	6.3e-09	-0.65	0.51	0.49	FALSE
8	GTEx	Artery Aorta	AC091133.1	0.10	0.07	lasso	5	0.07	1.2e-04	-5.45	5.8	7.9e-09	-0.65	0.30	0.47	FALSE
11	GTEx	Artery Aorta	RP11-6N17.10	0.20	0.07	enet	24	0.14	3.5e-08	-4.94	-5.7	9.0e-09	0.11	0.44	0.22	FALSE
50	GTEx	Pancreas	RP11-6N17.9	0.15	0.04	lasso	5	0.04	9.3e-03	-2.25	-5.7	9.2e-09	0.07	0.13	0.17	FALSE
63	GTEx	Thyroid	SNF8	0.11	0.08	lasso	3	0.07	2.5e-06	-5.31	5.7	9.5e-09	-0.61	0.89	0.08	FALSE
15	GTEx	Brain Cerebellar Hemisphere	CDK5RAP3	0.22	0.10	lasso	6	0.09	2.6e-03	4.67	-5.7	1.2e-08	0.09	0.08	0.42	FALSE
26	GTEx	Esophagus Gastroesophageal Junction	CDK5RAP3	0.21	0.09	lasso	6	0.07	1.2e-03	-4.94	-5.7	1.2e-08	0.10	0.09	0.50	FALSE
44	GTEx	Nerve Tibial	CDK5RAP3	0.41	0.35	enet	23	0.36	6.1e-27	-4.94	-5.7	1.2e-08	0.12	0.90	0.10	FALSE
47	GTEx	Nerve Tibial	RP11-6N17.10	0.28	0.19	lasso	8	0.19	1.6e-13	-4.94	-5.7	1.4e-08	0.12	0.90	0.10	FALSE
76	The Cancer Genome Atlas	Prostate Adenocarcinoma	SNF8	0.05	0.06	blup	47	0.06	1.0e-06	-6.50	5.7	1.4e-08	-0.64	0.04	0.96	FALSE
60	GTEx	Testis	RP11-6N17.4	0.14	0.02	lasso	10	0.02	4.8e-02	5.57	5.6	1.8e-08	-0.07	0.14	0.72	FALSE
40	GTEx	Lung	KANSL1	0.34	0.07	enet	30	0.11	1.7e-08	4.55	-5.6	2.0e-08	0.06	0.00	0.91	FALSE
33	GTEx	Heart Atrial Appendage	CDK5RAP3	0.13	0.00	enet	18	0.04	5.1e-03	1.07	-5.6	2.1e-08	0.10	0.09	0.05	FALSE
45	GTEx	Nerve Tibial	UBE2Z	0.12	0.04	enet	16	0.05	1.5e-04	-5.45	5.6	2.1e-08	-0.60	0.89	0.01	FALSE
14	GTEx	Brain Caudate basal ganglia	RP11-6N17.9	0.45	-0.01	enet	28	0.16	3.3e-05	-0.53	-5.6	2.4e-08	0.09	0.06	0.15	FALSE
57	GTEx	Stomach	RP11-6N17.9	0.13	0.02	lasso	6	0.04	8.0e-03	4.99	-5.6	2.6e-08	0.06	0.11	0.70	FALSE
10	GTEx	Artery Aorta	RP11-6N17.9	0.23	0.12	enet	19	0.19	9.5e-11	-4.94	-5.5	2.9e-08	0.09	0.93	0.07	FALSE
25	GTEx	Colon Sigmoid	NSFP1	0.51	0.28	enet	11	0.33	2.3e-12	5.18	5.5	3.0e-08	0.03	0.00	1.00	FALSE
77	The Cancer Genome Atlas	Thyroid Carcinoma	SNF8	0.16	0.18	lasso	7	0.18	5.9e-17	-5.45	5.5	3.8e-08	-0.64	0.45	0.55	FALSE
7	GTEx	Artery Aorta	SNF8	0.12	0.12	lasso	6	0.10	2.3e-06	-5.45	5.5	4.0e-08	-0.63	0.68	0.23	FALSE
53	GTEx	Pituitary	NSFP1	0.52	0.36	lasso	5	0.36	5.6e-10	5.18	5.5	4.2e-08	0.03	0.00	1.00	FALSE
34	GTEx	Heart Atrial Appendage	ATP5G1	0.22	0.10	enet	6	0.13	1.3e-06	-5.44	5.5	4.3e-08	-0.62	0.95	0.01	FALSE
6	GTEx	Artery Aorta	CDK5RAP3	0.26	0.22	lasso	11	0.25	5.8e-14	-4.94	-5.5	4.9e-08	0.12	0.91	0.09	FALSE
58	GTEx	Testis	SNF8	0.23	0.11	lasso	5	0.08	1.6e-04	-5.45	5.4	5.2e-08	-0.62	0.68	0.08	FALSE
74	The Cancer Genome Atlas	Prostate Adenocarcinoma	CBX1	0.03	0.04	lasso	4	0.04	3.7e-05	5.62	-5.4	5.6e-08	0.07	0.01	0.99	FALSE
68	METSIM	Adipose	LRRC37A	0.56	0.25	lasso	5	0.32	5.5e-49	5.18	5.4	5.7e-08	0.01	0.00	1.00	FALSE
41	GTEx	Muscle Skeletal	ATP5G1	0.13	0.08	enet	18	0.07	5.1e-07	-5.31	5.4	6.1e-08	-0.67	0.92	0.08	FALSE
23	GTEx	Cells Transformed fibroblasts	AC091133.1	0.14	0.07	enet	22	0.09	1.9e-07	-5.30	5.4	6.4e-08	-0.60	0.88	0.08	FALSE
66	GTEx	Uterus	CDK5RAP3	0.41	0.28	lasso	5	0.26	4.5e-06	-4.94	-5.4	6.5e-08	0.11	0.11	0.06	FALSE
67	GTEx	Uterus	RP11-6N17.10	0.43	0.26	lasso	6	0.24	1.3e-05	-4.94	-5.4	6.9e-08	0.12	0.09	0.08	FALSE
16	GTEx	Brain Cerebellar Hemisphere	RP11-6N17.10	0.21	0.16	lasso	5	0.13	3.8e-04	4.67	-5.4	7.1e-08	0.09	0.09	0.45	FALSE
20	GTEx	Brain Nucleus accumbens basal ganglia	CDK5RAP3	0.21	0.04	lasso	4	0.02	7.2e-02	5.54	-5.4	8.1e-08	0.08	0.08	0.41	FALSE
36	GTEx	Heart Atrial Appendage	NSFP1	0.47	0.25	lasso	4	0.29	2.4e-13	5.18	5.3	9.6e-08	0.02	0.00	1.00	FALSE
30	GTEx	Esophagus Muscularis	ATP5G1	0.09	0.06	lasso	5	0.05	4.5e-04	-5.30	5.3	9.7e-08	-0.60	0.17	0.51	FALSE
24	GTEx	Colon Sigmoid	ARL17A	0.66	0.47	lasso	10	0.50	4.2e-20	5.18	5.3	1.0e-07	0.02	0.00	1.00	FALSE
12	GTEx	Artery Tibial	ARL17A	0.69	0.37	lasso	9	0.44	5.4e-38	5.18	5.3	1.1e-07	0.02	0.00	1.00	FALSE
18	GTEx	Brain Cortex	ATP5G1	0.16	0.15	lasso	2	0.14	1.3e-04	-5.30	5.3	1.1e-07	-0.60	0.15	0.25	FALSE
35	GTEx	Heart Atrial Appendage	ARL17A	0.39	0.20	lasso	4	0.22	5.3e-10	5.18	5.3	1.1e-07	0.02	0.00	1.00	FALSE
73	The Cancer Genome Atlas	Brain Lower Grade Glioma	TTLL6	0.03	0.00	blup	59	0.02	2.7e-03	-4.50	-5.3	1.1e-07	0.54	0.02	0.83	FALSE
9	GTEx	Artery Aorta	NSFP1	0.40	0.19	lasso	5	0.24	3.3e-13	5.18	5.3	1.2e-07	0.02	0.00	1.00	FALSE
21	GTEx	Brain Putamen basal ganglia	CDK5RAP3	0.26	0.10	lasso	3	0.13	5.1e-04	-4.94	-5.2	1.5e-07	0.07	0.05	0.15	FALSE
29	GTEx	Esophagus Muscularis	COPZ2	0.14	0.04	lasso	5	0.06	1.3e-04	3.69	5.3	1.5e-07	-0.05	0.18	0.04	FALSE
46	GTEx	Nerve Tibial	RP11-6N17.9	0.29	0.27	lasso	4	0.27	2.1e-19	-4.94	-5.2	1.5e-07	0.12	0.90	0.10	FALSE
52	GTEx	Pituitary	ARL17B	0.27	0.22	enet	6	0.21	4.7e-06	5.18	5.3	1.5e-07	0.03	0.00	0.95	FALSE
71	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATP5G1	0.08	0.02	enet	7	0.02	3.1e-03	-5.84	5.2	1.5e-07	-0.59	0.02	0.77	FALSE
13	GTEx	Artery Tibial	RP11-6N17.9	0.16	0.14	lasso	4	0.12	6.2e-10	-4.94	-5.2	1.6e-07	0.12	0.90	0.10	FALSE
51	GTEx	Pituitary	ARL17A	0.63	0.43	lasso	6	0.42	8.6e-12	5.18	5.2	1.6e-07	0.03	0.00	1.00	FALSE
69	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNF8	0.01	0.01	blup	47	0.01	9.1e-03	-3.72	5.2	1.6e-07	-0.60	0.06	0.23	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CDK5RAP3	0.15	0.12	bslmm	392	0.14	3.6e-16	5.10	-5.2	1.7e-07	0.09	0.46	0.54	FALSE
55	GTEx	Skin Sun Exposed Lower leg	KANSL1	0.39	0.11	enet	20	0.16	6.8e-13	4.55	-5.2	1.9e-07	-0.01	0.00	0.97	FALSE
17	GTEx	Brain Cerebellum	ATP5G1	0.22	0.26	lasso	3	0.24	8.2e-08	-5.21	5.2	2.0e-07	-0.59	0.81	0.11	FALSE
32	GTEx	Esophagus Muscularis	NSFP1	0.42	0.22	enet	16	0.24	5.0e-15	5.18	5.2	2.0e-07	0.03	0.00	1.00	FALSE
62	GTEx	Thyroid	ATP5G1	0.09	0.04	enet	19	0.10	6.9e-08	-5.30	5.2	2.0e-07	-0.66	0.19	0.78	FALSE
4	GTEx	Adipose Subcutaneous	KANSL1	0.35	0.09	enet	13	0.12	1.1e-09	4.55	-5.2	2.1e-07	0.03	0.00	0.97	FALSE
39	GTEx	Liver	NSFP1	0.27	0.24	lasso	2	0.22	6.3e-07	5.18	5.2	2.1e-07	0.04	0.00	0.99	FALSE
59	GTEx	Testis	LRRC37A	0.71	0.46	enet	10	0.55	5.7e-29	5.18	5.2	2.4e-07	0.01	0.00	1.00	FALSE
70	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CBX1	0.03	0.01	lasso	3	0.01	8.7e-03	5.54	-5.2	2.5e-07	0.09	0.01	0.82	FALSE
5	GTEx	Adrenal Gland	ARL17A	0.52	0.01	lasso	7	0.19	2.2e-07	5.18	5.1	2.7e-07	0.02	0.00	0.99	FALSE
27	GTEx	Esophagus Gastroesophageal Junction	ARL17A	0.53	0.26	enet	9	0.37	2.0e-14	3.34	5.1	2.7e-07	0.01	0.00	1.00	FALSE