[Hub]/) : Traits : Arm fat percentage (right) :

chr17:43,871,147-47,718,188

Best TWAS P=8.36e-13 · Best GWAS P=2.04e-16 conditioned to 0.000199

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATP5G1 0.07 0.05 lasso 3 0.06 4.7e-08 -6.20 6.3 2.4e-10 -0.62 0.94 0.06 FALSE
2 CommonMind Brain Pre-frontal Cortex CDK5RAP3 0.15 0.12 bslmm 392 0.14 3.6e-16 5.10 -5.2 1.7e-07 0.09 0.46 0.54 FALSE
3 CommonMind Brain Pre-frontal Cortex SNF8 0.08 0.07 lasso 5 0.08 9.3e-10 -5.58 7.2 8.4e-13 -0.84 0.08 0.92 TRUE
4 GTEx Adipose Subcutaneous KANSL1 0.35 0.09 enet 13 0.12 1.1e-09 4.55 -5.2 2.1e-07 0.03 0.00 0.97 FALSE
5 GTEx Adrenal Gland ARL17A 0.52 0.01 lasso 7 0.19 2.2e-07 5.18 5.1 2.7e-07 0.02 0.00 0.99 FALSE
6 GTEx Artery Aorta CDK5RAP3 0.26 0.22 lasso 11 0.25 5.8e-14 -4.94 -5.5 4.9e-08 0.12 0.91 0.09 FALSE
7 GTEx Artery Aorta SNF8 0.12 0.12 lasso 6 0.10 2.3e-06 -5.45 5.5 4.0e-08 -0.63 0.68 0.23 FALSE
8 GTEx Artery Aorta AC091133.1 0.10 0.07 lasso 5 0.07 1.2e-04 -5.45 5.8 7.9e-09 -0.65 0.30 0.47 FALSE
9 GTEx Artery Aorta NSFP1 0.40 0.19 lasso 5 0.24 3.3e-13 5.18 5.3 1.2e-07 0.02 0.00 1.00 FALSE
10 GTEx Artery Aorta RP11-6N17.9 0.23 0.12 enet 19 0.19 9.5e-11 -4.94 -5.5 2.9e-08 0.09 0.93 0.07 FALSE
11 GTEx Artery Aorta RP11-6N17.10 0.20 0.07 enet 24 0.14 3.5e-08 -4.94 -5.7 9.0e-09 0.11 0.44 0.22 FALSE
12 GTEx Artery Tibial ARL17A 0.69 0.37 lasso 9 0.44 5.4e-38 5.18 5.3 1.1e-07 0.02 0.00 1.00 FALSE
13 GTEx Artery Tibial RP11-6N17.9 0.16 0.14 lasso 4 0.12 6.2e-10 -4.94 -5.2 1.6e-07 0.12 0.90 0.10 FALSE
14 GTEx Brain Caudate basal ganglia RP11-6N17.9 0.45 -0.01 enet 28 0.16 3.3e-05 -0.53 -5.6 2.4e-08 0.09 0.06 0.15 FALSE
15 GTEx Brain Cerebellar Hemisphere CDK5RAP3 0.22 0.10 lasso 6 0.09 2.6e-03 4.67 -5.7 1.2e-08 0.09 0.08 0.42 FALSE
16 GTEx Brain Cerebellar Hemisphere RP11-6N17.10 0.21 0.16 lasso 5 0.13 3.8e-04 4.67 -5.4 7.1e-08 0.09 0.09 0.45 FALSE
17 GTEx Brain Cerebellum ATP5G1 0.22 0.26 lasso 3 0.24 8.2e-08 -5.21 5.2 2.0e-07 -0.59 0.81 0.11 FALSE
18 GTEx Brain Cortex ATP5G1 0.16 0.15 lasso 2 0.14 1.3e-04 -5.30 5.3 1.1e-07 -0.60 0.15 0.25 FALSE
19 GTEx Brain Cortex ARL17A 0.35 0.20 lasso 6 0.25 1.7e-07 5.18 6.2 5.4e-10 0.01 0.00 0.97 FALSE
20 GTEx Brain Nucleus accumbens basal ganglia CDK5RAP3 0.21 0.04 lasso 4 0.02 7.2e-02 5.54 -5.4 8.1e-08 0.08 0.08 0.41 FALSE
21 GTEx Brain Putamen basal ganglia CDK5RAP3 0.26 0.10 lasso 3 0.13 5.1e-04 -4.94 -5.2 1.5e-07 0.07 0.05 0.15 FALSE
22 GTEx Cells Transformed fibroblasts SNF8 0.12 0.10 lasso 3 0.12 5.1e-09 -5.44 6.0 2.3e-09 -0.66 0.99 0.01 FALSE
23 GTEx Cells Transformed fibroblasts AC091133.1 0.14 0.07 enet 22 0.09 1.9e-07 -5.30 5.4 6.4e-08 -0.60 0.88 0.08 FALSE
24 GTEx Colon Sigmoid ARL17A 0.66 0.47 lasso 10 0.50 4.2e-20 5.18 5.3 1.0e-07 0.02 0.00 1.00 FALSE
25 GTEx Colon Sigmoid NSFP1 0.51 0.28 enet 11 0.33 2.3e-12 5.18 5.5 3.0e-08 0.03 0.00 1.00 FALSE
26 GTEx Esophagus Gastroesophageal Junction CDK5RAP3 0.21 0.09 lasso 6 0.07 1.2e-03 -4.94 -5.7 1.2e-08 0.10 0.09 0.50 FALSE
27 GTEx Esophagus Gastroesophageal Junction ARL17A 0.53 0.26 enet 9 0.37 2.0e-14 3.34 5.1 2.7e-07 0.01 0.00 1.00 FALSE
28 GTEx Esophagus Gastroesophageal Junction RP11-6N17.9 0.18 0.14 lasso 3 0.09 4.9e-04 -4.94 -6.1 1.3e-09 0.12 0.03 0.73 FALSE
29 GTEx Esophagus Muscularis COPZ2 0.14 0.04 lasso 5 0.06 1.3e-04 3.69 5.3 1.5e-07 -0.05 0.18 0.04 FALSE
30 GTEx Esophagus Muscularis ATP5G1 0.09 0.06 lasso 5 0.05 4.5e-04 -5.30 5.3 9.7e-08 -0.60 0.17 0.51 FALSE
31 GTEx Esophagus Muscularis SNF8 0.08 0.03 lasso 3 0.01 5.7e-02 -6.50 6.4 1.7e-10 -0.71 0.03 0.77 FALSE
32 GTEx Esophagus Muscularis NSFP1 0.42 0.22 enet 16 0.24 5.0e-15 5.18 5.2 2.0e-07 0.03 0.00 1.00 FALSE
33 GTEx Heart Atrial Appendage CDK5RAP3 0.13 0.00 enet 18 0.04 5.1e-03 1.07 -5.6 2.1e-08 0.10 0.09 0.05 FALSE
34 GTEx Heart Atrial Appendage ATP5G1 0.22 0.10 enet 6 0.13 1.3e-06 -5.44 5.5 4.3e-08 -0.62 0.95 0.01 FALSE
35 GTEx Heart Atrial Appendage ARL17A 0.39 0.20 lasso 4 0.22 5.3e-10 5.18 5.3 1.1e-07 0.02 0.00 1.00 FALSE
36 GTEx Heart Atrial Appendage NSFP1 0.47 0.25 lasso 4 0.29 2.4e-13 5.18 5.3 9.6e-08 0.02 0.00 1.00 FALSE
37 GTEx Heart Left Ventricle ATP5G1 0.24 0.22 lasso 4 0.22 9.3e-12 -6.04 6.6 5.0e-11 -0.64 1.00 0.00 FALSE
38 GTEx Liver ARL17A 0.34 0.18 lasso 9 0.18 9.8e-06 5.18 6.3 3.7e-10 0.04 0.00 0.94 TRUE
39 GTEx Liver NSFP1 0.27 0.24 lasso 2 0.22 6.3e-07 5.18 5.2 2.1e-07 0.04 0.00 0.99 FALSE
40 GTEx Lung KANSL1 0.34 0.07 enet 30 0.11 1.7e-08 4.55 -5.6 2.0e-08 0.06 0.00 0.91 FALSE
41 GTEx Muscle Skeletal ATP5G1 0.13 0.08 enet 18 0.07 5.1e-07 -5.31 5.4 6.1e-08 -0.67 0.92 0.08 FALSE
42 GTEx Muscle Skeletal UBE2Z 0.06 0.02 lasso 8 0.03 9.8e-04 -6.04 6.1 9.8e-10 -0.66 0.41 0.47 FALSE
43 GTEx Muscle Skeletal AC003665.1 0.05 0.03 enet 8 0.03 1.4e-03 4.81 6.1 1.3e-09 -0.11 0.12 0.73 FALSE
44 GTEx Nerve Tibial CDK5RAP3 0.41 0.35 enet 23 0.36 6.1e-27 -4.94 -5.7 1.2e-08 0.12 0.90 0.10 FALSE
45 GTEx Nerve Tibial UBE2Z 0.12 0.04 enet 16 0.05 1.5e-04 -5.45 5.6 2.1e-08 -0.60 0.89 0.01 FALSE
46 GTEx Nerve Tibial RP11-6N17.9 0.29 0.27 lasso 4 0.27 2.1e-19 -4.94 -5.2 1.5e-07 0.12 0.90 0.10 FALSE
47 GTEx Nerve Tibial RP11-6N17.10 0.28 0.19 lasso 8 0.19 1.6e-13 -4.94 -5.7 1.4e-08 0.12 0.90 0.10 FALSE
48 GTEx Ovary ATP5G1 0.15 0.08 enet 13 0.09 2.8e-03 -5.17 6.4 1.5e-10 -0.66 0.06 0.72 FALSE
49 GTEx Pancreas CDK5RAP3 0.11 -0.01 lasso 4 0.02 5.1e-02 4.67 -6.1 1.1e-09 0.04 0.09 0.18 FALSE
50 GTEx Pancreas RP11-6N17.9 0.15 0.04 lasso 5 0.04 9.3e-03 -2.25 -5.7 9.2e-09 0.07 0.13 0.17 FALSE
51 GTEx Pituitary ARL17A 0.63 0.43 lasso 6 0.42 8.6e-12 5.18 5.2 1.6e-07 0.03 0.00 1.00 FALSE
52 GTEx Pituitary ARL17B 0.27 0.22 enet 6 0.21 4.7e-06 5.18 5.3 1.5e-07 0.03 0.00 0.95 FALSE
53 GTEx Pituitary NSFP1 0.52 0.36 lasso 5 0.36 5.6e-10 5.18 5.5 4.2e-08 0.03 0.00 1.00 FALSE
54 GTEx Skin Not Sun Exposed Suprapubic UBE2Z 0.11 0.07 lasso 6 0.04 1.8e-03 -6.50 6.6 4.5e-11 -0.68 0.10 0.12 FALSE
55 GTEx Skin Sun Exposed Lower leg KANSL1 0.39 0.11 enet 20 0.16 6.8e-13 4.55 -5.2 1.9e-07 -0.01 0.00 0.97 FALSE
56 GTEx Skin Sun Exposed Lower leg UBE2Z 0.14 0.11 lasso 9 0.14 6.3e-12 -5.21 6.0 2.6e-09 -0.64 1.00 0.00 FALSE
57 GTEx Stomach RP11-6N17.9 0.13 0.02 lasso 6 0.04 8.0e-03 4.99 -5.6 2.6e-08 0.06 0.11 0.70 FALSE
58 GTEx Testis SNF8 0.23 0.11 lasso 5 0.08 1.6e-04 -5.45 5.4 5.2e-08 -0.62 0.68 0.08 FALSE
59 GTEx Testis LRRC37A 0.71 0.46 enet 10 0.55 5.7e-29 5.18 5.2 2.4e-07 0.01 0.00 1.00 FALSE
60 GTEx Testis RP11-6N17.4 0.14 0.02 lasso 10 0.02 4.8e-02 5.57 5.6 1.8e-08 -0.07 0.14 0.72 FALSE
61 GTEx Thyroid CDK5RAP3 0.21 0.14 lasso 5 0.18 1.6e-13 -4.94 -6.1 1.4e-09 0.13 0.90 0.10 FALSE
62 GTEx Thyroid ATP5G1 0.09 0.04 enet 19 0.10 6.9e-08 -5.30 5.2 2.0e-07 -0.66 0.19 0.78 FALSE
63 GTEx Thyroid SNF8 0.11 0.08 lasso 3 0.07 2.5e-06 -5.31 5.7 9.5e-09 -0.61 0.89 0.08 FALSE
64 GTEx Thyroid RP11-6N17.9 0.22 0.14 lasso 5 0.14 5.2e-11 -4.94 -5.9 2.9e-09 0.12 0.90 0.10 FALSE
65 GTEx Thyroid RP11-6N17.10 0.19 0.12 lasso 5 0.13 3.0e-10 -4.94 -6.3 3.8e-10 0.13 0.90 0.10 FALSE
66 GTEx Uterus CDK5RAP3 0.41 0.28 lasso 5 0.26 4.5e-06 -4.94 -5.4 6.5e-08 0.11 0.11 0.06 FALSE
67 GTEx Uterus RP11-6N17.10 0.43 0.26 lasso 6 0.24 1.3e-05 -4.94 -5.4 6.9e-08 0.12 0.09 0.08 FALSE
68 METSIM Adipose LRRC37A 0.56 0.25 lasso 5 0.32 5.5e-49 5.18 5.4 5.7e-08 0.01 0.00 1.00 FALSE
69 The Cancer Genome Atlas Breast Invasive Carcinoma SNF8 0.01 0.01 blup 47 0.01 9.1e-03 -3.72 5.2 1.6e-07 -0.60 0.06 0.23 FALSE
70 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CBX1 0.03 0.01 lasso 3 0.01 8.7e-03 5.54 -5.2 2.5e-07 0.09 0.01 0.82 FALSE
71 The Cancer Genome Atlas Brain Lower Grade Glioma ATP5G1 0.08 0.02 enet 7 0.02 3.1e-03 -5.84 5.2 1.5e-07 -0.59 0.02 0.77 FALSE
72 The Cancer Genome Atlas Brain Lower Grade Glioma SNF8 0.11 0.12 lasso 4 0.12 1.4e-13 -5.60 5.8 6.3e-09 -0.65 0.51 0.49 FALSE
73 The Cancer Genome Atlas Brain Lower Grade Glioma TTLL6 0.03 0.00 blup 59 0.02 2.7e-03 -4.50 -5.3 1.1e-07 0.54 0.02 0.83 FALSE
74 The Cancer Genome Atlas Prostate Adenocarcinoma CBX1 0.03 0.04 lasso 4 0.04 3.7e-05 5.62 -5.4 5.6e-08 0.07 0.01 0.99 FALSE
75 The Cancer Genome Atlas Prostate Adenocarcinoma CDK5RAP3 0.06 0.00 blup 62 0.03 1.0e-03 -3.64 -6.8 1.3e-11 0.07 0.01 0.52 TRUE
76 The Cancer Genome Atlas Prostate Adenocarcinoma SNF8 0.05 0.06 blup 47 0.06 1.0e-06 -6.50 5.7 1.4e-08 -0.64 0.04 0.96 FALSE
77 The Cancer Genome Atlas Thyroid Carcinoma SNF8 0.16 0.18 lasso 7 0.18 5.9e-17 -5.45 5.5 3.8e-08 -0.64 0.45 0.55 FALSE
78 The Cancer Genome Atlas Thyroid Carcinoma UBE2Z 0.13 0.09 lasso 4 0.12 2.7e-11 -5.44 6.0 2.0e-09 -0.64 0.05 0.95 FALSE