[Hub]/) : Traits : Arm fat percentage (right) :

chr8:8,092,025-12,751,157

Best TWAS P=1.17e-11 · Best GWAS P=4.91e-10 conditioned to 0.0211

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ERI1 0.05 0.00 enet 10 0.00 5.5e-01 4.3 -5.6 2.3e-08 -0.48 0.11 0.67 FALSE
2 GTEx Adipose Subcutaneous FAM85A 0.06 0.06 enet 10 0.07 3.3e-06 -4.4 5.3 9.3e-08 0.39 0.08 0.84 FALSE
3 GTEx Adrenal Gland FAM86B3P 0.16 0.00 enet 18 0.03 2.2e-02 3.8 -5.3 1.0e-07 -0.35 0.05 0.29 FALSE
4 GTEx Artery Aorta ERI1 0.11 0.08 lasso 5 0.10 5.1e-06 5.6 -5.1 2.8e-07 -0.53 0.06 0.93 FALSE
5 GTEx Artery Coronary AF131215.2 0.11 0.02 enet 27 0.05 6.5e-03 -3.9 5.3 9.4e-08 0.67 0.07 0.70 FALSE
6 GTEx Artery Tibial AF131215.2 0.07 0.03 enet 24 0.05 1.8e-04 -3.4 5.1 2.9e-07 0.64 0.10 0.88 FALSE
7 GTEx Cells Transformed fibroblasts ERI1 0.34 0.35 lasso 7 0.35 1.9e-27 5.6 -5.9 3.9e-09 -0.50 0.02 0.98 FALSE
8 GTEx Esophagus Gastroesophageal Junction MSRA 0.11 -0.01 enet 30 -0.01 8.0e-01 6.0 -5.8 6.7e-09 -0.45 0.14 0.31 FALSE
9 GTEx Esophagus Muscularis ERI1 0.12 0.09 enet 13 0.08 7.7e-06 4.2 -5.2 2.5e-07 -0.52 0.45 0.54 FALSE
10 GTEx Heart Atrial Appendage MFHAS1 0.34 0.23 enet 56 0.19 5.7e-09 -5.2 5.6 1.8e-08 0.36 0.03 0.97 FALSE
11 GTEx Nerve Tibial ERI1 0.07 0.01 enet 16 0.01 4.2e-02 -3.8 -5.6 1.8e-08 -0.50 0.13 0.64 FALSE
12 GTEx Prostate AF131215.2 0.18 0.02 lasso 6 0.02 9.6e-02 3.2 5.2 2.0e-07 0.85 0.09 0.46 FALSE
13 GTEx Skin Sun Exposed Lower leg FAM85A 0.09 0.04 enet 28 0.04 1.4e-04 -4.4 5.8 8.1e-09 0.36 0.07 0.81 FALSE
14 NTR Blood MSRA 0.02 0.01 blup 833 0.01 2.3e-05 3.9 -6.8 1.2e-11 -0.66 0.32 0.68 TRUE
15 ROSMAP Brain Pre-frontal Cortex RP11-481A20.11 0.06 0.04 blup 286 0.04 2.2e-06 3.9 5.4 7.5e-08 0.52 0.39 0.55 FALSE
16 The Cancer Genome Atlas Bladder Urothelial Carcinoma ERI1 0.05 0.01 blup 72 0.01 5.0e-02 5.6 -5.2 1.6e-07 -0.37 0.00 0.87 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma ERI1 0.06 0.04 blup 72 0.04 1.5e-05 5.3 -5.2 1.6e-07 -0.45 0.01 0.99 FALSE