[Hub]/) : Traits : Arm fat percentage (right) :

chr8:21,249,296-24,094,711

Best TWAS P=2.66e-09 · Best GWAS P=3.12e-09 conditioned to 0.59

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HR 0.06 0.01 bslmm 452 0.03 3.8e-05 -3.3 5.7 9.4e-09 0.51 0.05 0.85 FALSE
2 GTEx Adipose Subcutaneous NUDT18 0.10 0.07 enet 10 0.07 2.3e-06 5.8 5.3 1.0e-07 0.87 0.01 0.99 FALSE
3 GTEx Cells Transformed fibroblasts SLC25A37 0.13 0.05 lasso 5 0.04 3.0e-04 -5.9 5.4 5.3e-08 0.02 0.00 1.00 TRUE
4 GTEx Cells Transformed fibroblasts FAM160B2 0.18 0.09 lasso 5 0.10 4.0e-08 -5.7 5.4 5.9e-08 0.68 0.02 0.98 FALSE
5 GTEx Cells Transformed fibroblasts NUDT18 0.10 0.04 enet 6 0.03 4.7e-03 5.2 5.8 8.1e-09 0.89 0.01 0.93 FALSE
6 GTEx Cells Transformed fibroblasts AC091171.1 0.15 0.06 lasso 2 0.05 2.2e-04 -5.7 5.6 1.6e-08 0.69 0.03 0.95 FALSE
7 GTEx Esophagus Mucosa FAM160B2 0.15 0.05 enet 19 0.09 1.7e-06 5.6 5.1 2.6e-07 0.77 0.01 0.99 FALSE
8 GTEx Esophagus Mucosa NUDT18 0.21 0.23 enet 8 0.23 3.9e-15 -5.1 -5.3 1.2e-07 -0.73 0.23 0.77 FALSE
9 GTEx Esophagus Mucosa AC091171.1 0.14 0.07 lasso 4 0.05 2.2e-04 5.8 6.0 2.7e-09 0.94 0.01 0.99 TRUE
10 GTEx Skin Not Sun Exposed Suprapubic NUDT18 0.31 0.15 enet 13 0.22 4.6e-12 -5.1 -5.4 5.3e-08 -0.71 0.21 0.78 FALSE
11 GTEx Skin Sun Exposed Lower leg NUDT18 0.21 0.20 lasso 4 0.20 3.3e-16 -5.1 -5.2 2.3e-07 -0.71 0.25 0.75 FALSE
12 GTEx Testis NUDT18 0.42 0.40 lasso 4 0.41 1.3e-19 -5.1 -5.1 2.8e-07 -0.70 0.20 0.80 FALSE
13 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma NUDT18 0.09 0.03 blup 45 0.08 1.3e-04 -5.2 -5.7 1.3e-08 -0.78 0.05 0.93 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma FAM160B2 0.06 0.07 lasso 1 0.06 2.3e-04 5.6 5.6 2.0e-08 0.93 0.01 0.92 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NUDT18 0.10 0.16 lasso 2 0.16 2.3e-09 -5.2 -5.2 2.0e-07 -0.71 0.06 0.94 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma FAM160B2 0.04 0.01 lasso 4 0.01 2.6e-02 -5.1 5.1 2.7e-07 0.60 0.04 0.59 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma NUDT18 0.11 0.22 lasso 6 0.22 3.6e-24 -5.7 -5.7 1.2e-08 -0.78 0.03 0.97 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FAM160B2 0.02 0.02 blup 53 0.02 1.8e-03 -5.7 5.2 2.6e-07 0.69 0.04 0.79 FALSE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NUDT18 0.06 0.08 lasso 3 0.07 1.6e-08 -5.2 -5.2 2.2e-07 -0.71 0.08 0.92 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma FAM160B2 0.05 0.01 enet 11 0.03 1.7e-04 -5.5 5.4 6.4e-08 0.70 0.02 0.94 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma NUDT18 0.17 0.25 blup 45 0.27 6.2e-28 -5.1 -5.2 2.4e-07 -0.69 0.10 0.90 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma FAM160B2 0.08 0.06 lasso 4 0.05 1.4e-05 -5.7 5.6 2.5e-08 0.64 0.02 0.97 FALSE
23 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NUDT18 0.15 0.17 lasso 4 0.12 2.3e-04 -5.5 -5.8 6.8e-09 -0.78 0.02 0.95 FALSE