TWAS
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Models
Genes
Traits
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Traits
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Arm fat percentage (right)
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chr10:98,916,782-100,704,597
Best TWAS P=1.12e-10 · Best GWAS P=3.1e-15 conditioned to 0.00158
99M
99.2M
99.4M
99.6M
99.8M
100M
100.2M
100.4M
100.6M
100.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
CRTAC1
0.06
0.04
lasso
2
0.05
3.6e-07
4.3
-6.5
1.1e-10
0.63
0.43
0.54
TRUE
2
CommonMind
Brain Pre-frontal Cortex
GOLGA7B
0.07
0.00
enet
23
0.04
1.3e-05
-1.3
-6.0
2.2e-09
0.46
0.59
0.05
TRUE
3
GTEx
Nerve Tibial
R3HCC1L
0.06
0.07
enet
8
0.05
1.1e-04
-5.2
-5.2
2.1e-07
0.37
0.78
0.01
TRUE