[Hub]/) : Traits : Arm fat mass (right) :

chr16:86,671-1,137,354

Best TWAS P=2.4e-11 · Best GWAS P=2.36e-11 conditioned to 0.0275

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial AXIN1 0.11 0.09 lasso 2 0.06 3.9e-05 -6.0 5.3 1.2e-07 -0.78 0.08 0.90 FALSE
2 GTEx Nerve Tibial PDIA2 0.12 0.01 enet 13 0.06 4.4e-05 -5.8 6.2 7.0e-10 -0.77 0.03 0.96 FALSE
3 GTEx Nerve Tibial ARHGDIG 0.13 0.07 lasso 2 0.07 8.0e-06 -6.0 5.9 3.5e-09 -0.74 0.05 0.81 FALSE
4 GTEx Testis AXIN1 0.36 0.29 lasso 3 0.28 4.3e-13 -6.0 -5.7 1.1e-08 0.81 0.08 0.92 FALSE
5 GTEx Whole Blood NME4 0.12 0.03 lasso 5 0.04 3.0e-04 2.9 5.7 1.0e-08 -0.62 0.02 0.96 FALSE
6 ROSMAP Brain Pre-frontal Cortex PDIA2 0.15 0.07 lasso 8 0.10 5.2e-13 -4.9 -6.2 5.6e-10 0.77 0.06 0.94 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma AXIN1 0.03 0.01 blup 88 0.01 7.7e-03 -5.9 6.7 2.4e-11 -0.80 0.01 0.74 TRUE
8 The Cancer Genome Atlas Brain Lower Grade Glioma LOC100134368 0.03 0.00 enet 5 0.01 2.8e-02 -3.6 -6.4 1.7e-10 0.58 0.01 0.57 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC100134368 0.08 0.07 blup 48 0.06 1.9e-03 2.9 -5.2 2.5e-07 0.47 0.05 0.15 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma LOC100134368 0.05 0.00 blup 48 0.04 2.5e-05 -4.9 -6.4 1.5e-10 0.65 0.02 0.83 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma LOC100134368 0.06 0.05 blup 47 0.07 3.9e-07 2.9 -5.8 5.3e-09 0.53 0.41 0.44 FALSE