Best TWAS P=1.35e-07 · Best GWAS P=2.55e-07 conditioned to 3.29e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RPL13 | 0.10 | 0.08 | enet | 8 | 0.09 | 3.7e-07 | 4.5 | -5.3 | 1.4e-07 | 0.10 | 0.04 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | SPG7 | 0.13 | 0.01 | blup | 59 | 0.03 | 5.8e-03 | -3.7 | -5.2 | 1.6e-07 | 0.18 | 0.01 | 0.21 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | SPG7 | 0.10 | 0.09 | lasso | 4 | 0.11 | 1.9e-10 | 4.7 | -5.2 | 2.0e-07 | 0.17 | 0.01 | 0.98 | FALSE |