Best TWAS P=3.07e-10 · Best GWAS P=1.01e-19 conditioned to 5.54e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SRR | 0.16 | 0.16 | lasso | 9 | 0.18 | 1.9e-14 | -4.8 | 5.6 | 2.4e-08 | -0.07 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adrenal Gland | SRR | 0.38 | 0.37 | lasso | 6 | 0.38 | 8.1e-15 | -4.3 | 5.1 | 2.9e-07 | -0.05 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Liver | SRR | 0.31 | 0.00 | lasso | 7 | 0.00 | 3.0e-01 | -6.8 | 6.3 | 3.1e-10 | -0.36 | 0.06 | 0.14 | TRUE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | SRR | 0.16 | 0.03 | blup | 61 | 0.02 | 8.7e-02 | -4.6 | 5.2 | 2.3e-07 | -0.08 | 0.02 | 0.50 | FALSE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | SGSM2 | 0.13 | 0.01 | blup | 81 | 0.01 | 1.1e-01 | 4.6 | -5.8 | 8.6e-09 | 0.07 | 0.01 | 0.61 | TRUE |