[Hub]/) : Traits : Arm fat mass (right) :

chr17:4,137,919-6,068,117

Best TWAS P=1.29e-09 · Best GWAS P=6.63e-08 conditioned to 0.396

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RABEP1 0.13 0.03 lasso 13 0.02 7.2e-02 -4.3 -5.2 1.6e-07 -0.80 0.04 0.81 FALSE
2 GTEx Brain Putamen basal ganglia AC012146.7 0.30 0.03 enet 23 0.03 7.6e-02 4.2 -6.1 1.3e-09 -0.45 0.08 0.24 TRUE
3 GTEx Esophagus Gastroesophageal Junction DHX33 0.12 0.08 lasso 5 0.07 1.8e-03 5.4 -5.2 1.7e-07 -0.96 0.02 0.96 FALSE
4 GTEx Esophagus Gastroesophageal Junction RABEP1 0.19 -0.01 lasso 13 0.00 4.2e-01 4.4 -5.3 1.3e-07 -0.82 0.04 0.76 FALSE
5 GTEx Esophagus Gastroesophageal Junction GP1BA 0.35 0.16 lasso 11 0.18 5.9e-07 4.3 5.8 6.8e-09 0.56 0.12 0.78 FALSE
6 GTEx Esophagus Muscularis RABEP1 0.13 0.09 lasso 10 0.10 2.1e-06 5.4 -5.2 2.2e-07 -0.94 0.02 0.97 FALSE
7 GTEx Skin Sun Exposed Lower leg AC012146.7 0.21 0.07 enet 17 0.18 1.3e-14 2.8 -5.3 1.5e-07 -0.45 0.90 0.02 FALSE
8 METSIM Adipose SLC52A1 0.07 0.02 lasso 7 0.05 1.8e-07 4.1 -5.1 3.0e-07 -0.20 0.45 0.49 FALSE
9 ROSMAP Brain Pre-frontal Cortex RABEP1 0.20 0.22 bslmm 546 0.20 7.4e-25 4.4 -5.3 9.0e-08 -0.75 0.29 0.68 FALSE
10 ROSMAP Brain Pre-frontal Cortex RPAIN 0.06 0.06 lasso 3 0.06 3.1e-08 5.3 -5.7 1.2e-08 -0.98 0.00 1.00 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme NUP88 0.12 0.07 enet 12 0.09 1.2e-03 4.4 -5.2 1.9e-07 -0.78 0.02 0.66 FALSE
12 The Cancer Genome Atlas Glioblastoma Multiforme RABEP1 0.23 0.13 blup 79 0.15 3.4e-05 4.5 -5.8 7.8e-09 -0.77 0.05 0.84 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma GP1BA 0.02 0.02 blup 49 0.02 9.3e-03 4.2 5.3 8.6e-08 0.33 0.01 0.62 FALSE
14 The Cancer Genome Atlas Soft Tissue Sarcoma INCA1 0.06 0.00 enet 11 0.00 1.7e-01 4.3 5.4 7.8e-08 0.30 0.00 0.34 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma RABEP1 0.04 0.03 enet 5 0.03 1.5e-03 -4.4 -5.6 1.8e-08 -0.67 0.08 0.82 TRUE