[Hub]/) : Traits : Arm fat mass (right) : ← →

chr17:44,788,310-47,718,188

Best TWAS P=8.49e-12 · Best GWAS P=9.84e-14 conditioned to 0.000148

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATP5G1	0.07	0.05	lasso	3	0.06	4.7e-08	-5.12	5.7	9.3e-09	0.08	0.93	0.06	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CDK5RAP3	0.15	0.12	bslmm	392	0.14	3.6e-16	6.23	-6.1	9.5e-10	-0.78	0.46	0.54	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SNF8	0.08	0.07	lasso	5	0.08	9.3e-10	-4.92	6.1	1.4e-09	0.07	0.05	0.95	TRUE
4	GTEx	Artery Aorta	CDK5RAP3	0.26	0.22	lasso	11	0.25	5.8e-14	-4.73	-5.5	4.2e-08	-0.35	1.00	0.00	FALSE
5	GTEx	Artery Aorta	RP11-6N17.9	0.23	0.12	enet	19	0.19	9.5e-11	-4.73	-5.6	2.2e-08	-0.42	0.99	0.01	FALSE
6	GTEx	Artery Aorta	RP11-6N17.10	0.20	0.07	enet	24	0.14	3.5e-08	-4.73	-6.2	7.6e-10	-0.43	0.46	0.19	FALSE
7	GTEx	Artery Coronary	PNPO	0.13	0.00	lasso	4	-0.01	5.9e-01	4.56	5.2	2.1e-07	0.24	0.13	0.06	FALSE
8	GTEx	Artery Tibial	RP11-6N17.9	0.16	0.14	lasso	4	0.12	6.2e-10	-4.73	-5.2	2.6e-07	-0.31	1.00	0.00	FALSE
9	GTEx	Brain Caudate basal ganglia	RP11-6N17.9	0.45	-0.01	enet	28	0.16	3.3e-05	-0.90	-6.2	6.8e-10	-0.48	0.06	0.15	FALSE
10	GTEx	Brain Cerebellar Hemisphere	CDK5RAP3	0.22	0.10	lasso	6	0.09	2.6e-03	5.28	-6.4	1.5e-10	-0.74	0.08	0.42	FALSE
11	GTEx	Brain Cerebellar Hemisphere	RP11-6N17.10	0.21	0.16	lasso	5	0.13	3.8e-04	5.28	-6.0	2.5e-09	-0.73	0.09	0.45	FALSE
12	GTEx	Brain Nucleus accumbens basal ganglia	KPNB1	0.24	0.00	lasso	9	0.01	2.1e-01	0.91	-5.4	8.2e-08	-0.80	0.02	0.79	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	CDK5RAP3	0.21	0.04	lasso	4	0.02	7.2e-02	6.61	-6.3	2.5e-10	-0.78	0.08	0.41	FALSE
14	GTEx	Brain Nucleus accumbens basal ganglia	RP11-6N17.9	0.47	0.05	lasso	17	0.11	8.3e-04	5.89	-6.0	1.9e-09	-0.65	0.10	0.44	FALSE
15	GTEx	Cells Transformed fibroblasts	SNF8	0.12	0.10	lasso	3	0.12	5.1e-09	-4.77	5.3	1.5e-07	0.08	0.97	0.03	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	CDK5RAP3	0.21	0.09	lasso	6	0.07	1.2e-03	-4.73	-6.0	2.1e-09	-0.30	0.09	0.50	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	RP11-6N17.9	0.18	0.14	lasso	3	0.09	4.9e-04	-4.73	-6.2	4.9e-10	-0.49	0.03	0.73	FALSE
18	GTEx	Esophagus Muscularis	SNF8	0.08	0.03	lasso	3	0.01	5.7e-02	-5.69	5.5	3.2e-08	0.08	0.02	0.80	FALSE
19	GTEx	Heart Atrial Appendage	CDK5RAP3	0.13	0.00	enet	18	0.04	5.1e-03	1.74	-6.5	8.5e-11	-0.42	0.09	0.05	TRUE
20	GTEx	Heart Left Ventricle	ATP5G1	0.24	0.22	lasso	4	0.22	9.3e-12	-5.38	5.8	9.1e-09	0.12	0.97	0.03	FALSE
21	GTEx	Liver	ARL17A	0.34	0.18	lasso	9	0.18	9.8e-06	4.65	5.5	2.9e-08	-0.04	0.00	0.65	TRUE
22	GTEx	Muscle Skeletal	AC003665.1	0.05	0.03	enet	8	0.03	1.4e-03	5.37	6.8	1.2e-11	0.63	0.12	0.73	FALSE
23	GTEx	Nerve Tibial	CDK5RAP3	0.41	0.35	enet	23	0.36	6.1e-27	-4.73	-5.7	1.6e-08	-0.41	1.00	0.00	FALSE
24	GTEx	Nerve Tibial	RP11-6N17.9	0.29	0.27	lasso	4	0.27	2.1e-19	-4.73	-5.2	2.4e-07	-0.36	1.00	0.00	FALSE
25	GTEx	Nerve Tibial	RP11-6N17.10	0.28	0.19	lasso	8	0.19	1.6e-13	-4.73	-5.6	2.2e-08	-0.36	1.00	0.00	FALSE
26	GTEx	Ovary	ATP5G1	0.15	0.08	enet	13	0.09	2.8e-03	-4.38	5.4	8.5e-08	0.07	0.07	0.68	FALSE
27	GTEx	Pancreas	CDK5RAP3	0.11	-0.01	lasso	4	0.02	5.1e-02	5.28	-6.4	1.4e-10	-0.48	0.09	0.18	FALSE
28	GTEx	Pancreas	RP11-6N17.9	0.15	0.04	lasso	5	0.04	9.3e-03	-2.33	-6.1	1.1e-09	-0.47	0.13	0.17	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	UBE2Z	0.11	0.07	lasso	6	0.04	1.8e-03	-5.69	5.5	3.2e-08	0.08	0.10	0.14	FALSE
30	GTEx	Skin Sun Exposed Lower leg	UBE2Z	0.14	0.11	lasso	9	0.14	6.3e-12	-4.41	5.1	2.9e-07	0.07	0.99	0.01	FALSE
31	GTEx	Stomach	RP11-6N17.9	0.13	0.02	lasso	6	0.04	8.0e-03	5.70	-6.3	3.4e-10	-0.70	0.11	0.70	FALSE
32	GTEx	Testis	RP11-6N17.4	0.14	0.02	lasso	10	0.02	4.8e-02	6.57	6.5	7.1e-11	0.78	0.15	0.72	FALSE
33	GTEx	Thyroid	CDK5RAP3	0.21	0.14	lasso	5	0.18	1.6e-13	-4.73	-6.2	6.8e-10	-0.51	1.00	0.00	FALSE
34	GTEx	Thyroid	RP11-6N17.9	0.22	0.14	lasso	5	0.14	5.2e-11	-4.73	-6.0	2.1e-09	-0.44	1.00	0.00	FALSE
35	GTEx	Thyroid	RP11-6N17.10	0.19	0.12	lasso	5	0.13	3.0e-10	-4.73	-6.2	4.3e-10	-0.47	1.00	0.00	FALSE
36	GTEx	Uterus	CDK5RAP3	0.41	0.28	lasso	5	0.26	4.5e-06	-4.73	-5.2	2.2e-07	-0.24	0.11	0.05	FALSE
37	GTEx	Uterus	RP11-6N17.10	0.43	0.26	lasso	6	0.24	1.3e-05	-4.73	-5.1	3.0e-07	-0.24	0.09	0.07	FALSE
38	YFS	Blood	UBE2Z	0.06	0.03	enet	19	0.06	1.5e-18	2.78	5.6	1.7e-08	0.10	1.00	0.00	TRUE
39	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDK5RAP3	0.05	0.03	lasso	2	0.02	1.8e-05	5.70	-5.8	7.0e-09	-0.76	0.00	1.00	FALSE
40	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CBX1	0.03	0.01	lasso	3	0.01	8.7e-03	6.61	-6.1	1.2e-09	-0.80	0.01	0.82	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATP5G1	0.08	0.02	enet	7	0.02	3.1e-03	-4.89	5.4	6.3e-08	0.10	0.02	0.77	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	CBX1	0.03	0.04	lasso	4	0.04	3.7e-05	6.64	-6.5	7.9e-11	-0.84	0.01	0.99	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	CDK5RAP3	0.06	0.00	blup	62	0.03	1.0e-03	-3.83	-6.8	8.5e-12	-0.35	0.01	0.81	TRUE
44	The Cancer Genome Atlas	Thyroid Carcinoma	ATP5G1	0.19	0.03	lasso	3	0.08	4.4e-08	3.44	5.2	1.7e-07	0.08	0.01	0.99	FALSE
45	The Cancer Genome Atlas	Thyroid Carcinoma	UBE2Z	0.13	0.09	lasso	4	0.12	2.7e-11	-4.77	5.1	3.0e-07	0.06	0.04	0.96	FALSE